Conformalized Multiple Testing after Data-dependent Selection

Neural Information Processing Systems 

The task of distinguishing individuals of interest from a vast pool of candidates using predictive models has garnered significant attention in recent years. This task can be framed as a procedure, which aims at quantifying prediction uncertainty by controlling the false discovery rate (FDR) via conformal inference. In this paper, we tackle the challenge of conformalized multiple testing after data-dependent selection procedures. To guarantee the construction of valid test statistics that accurately capture the distorted distribution resulting from the selection process, we leverage a holdout labeled set to closely emulate the selective distribution. Our approach involves adaptively picking labeled data to create a calibration set based on the stability of the selection rule.