Review for NeurIPS paper: A Convolutional Auto-Encoder for Haplotype Assembly and Viral Quasispecies Reconstruction

Neural Information Processing Systems 

Weaknesses: As noted below, (1) it is not clear what the contribution of their method is, and (2) necessary details are missing from their evaluations. Also, at some points of their approach in preparing the dataset, they used some restrictions on some parameters but they didn't mention why they used these numbers. This is concerning, so I think they need to clarify why they used those parameters. For example, for TB they mention that: "Read alignment is performed using BWA-MEM (Li and Durbin, 2009), where the reads with mapping scores lower than 40 are filtered out for quality control." But for HIV they choose different approach: "Reads with mapping score lower than 60 and length shorter than 150 bp are filtered out for quality control".