Review for NeurIPS paper: Patch2Self: Denoising Diffusion MRI with Self-Supervised Learning

Neural Information Processing Systems 

One key difference between the proposed patch-based approach and the baseline Marchenko-Pastur is the patch-based nature of the former. Is smoother appearance of the images in figure 2 and the less noisy tractograms in figure 3 simply because the patch-based approach introduces more smoothing? That seems very likely to me. A potential big advantage of the Marchenko-Pastur is that it does not smooth so preserves detail. This is not tested in the qualitative evaluations of figures 2 and 3 or mentioned anywhere in the text.