Reviews: Generalisation of structural knowledge in the hippocampal-entorhinal system

It is an interesting study that tackles one of very important questions in computational neuroscience - how generalisation across stimuli and environments is achieved. It is similar to the concept of schemas, which are thought to primarily rely on frontal cortical areas. In this particular case the focus is on entorhinal grid cells and hippocampal place cells, which authors assert code for the environment and conjunction of environment and stimulus respectively. The authors present a computational model that aims to address the question of whether place cells encode a conjunctive outcome of environment and stimulus representations. It is an interesting hypothesis, which if shown convincingly, would be a major breakthrough in neuroscience.