Reviews: A Non-parametric Learning Method for Confidently Estimating Patient's Clinical State and Dynamics

Thank you for the submission. There are a few points of clinical clarity. The more targeted goal that is in line with other models in this area is to predict clinical deterioration (a shift in patient condition that requires a higher level of care). The goal of "clinical state" is less about understanding what it is but how shifts in the state drive an intervention (i.e. ICU transfer) (2) The authors should clarify the use case they describe.