Reviews: A state-space model for inferring effective connectivity of latent neural dynamics from simultaneous EEG/fMRI

This paper develops a novel method to infer directional relationships between cortical areas of the brain based on simultaneously acquired EEG and fMRI data. Specifically, the fMRI activations are used to select ROIs related to the paradigm of interest. This information is used in a coupled state-space and forward propagation model to identify robust spatial sources and directional connectivity. The authors use a variational Bayesian framework to infer the latent posteriors and noise covariances. They demonstrate the power of joint EEG/fMRI analysis using two simulated experiments and a real-world dataset.