The past decade has witnessed a groundbreaking rise of machine learning for human language analysis, with current methods capable of automatically accurately recovering various aspects of syntax and semantics - including sentence structure and grounded word meaning - from large data collections. Recent research showed the promise of such tools for analyzing acoustic communication in nonhuman species. We posit that machine learning will be the cornerstone of future collection, processing, and analysis of multimodal streams of data in animal communication studies, including bioacoustic, behavioral, biological, and environmental data. Cetaceans are unique non-human model species as they possess sophisticated acoustic communications, but utilize a very different encoding system that evolved in an aquatic rather than terrestrial medium. Sperm whales, in particular, with their highly-developed neuroanatomical features, cognitive abilities, social structures, and discrete click-based encoding make for an excellent starting point for advanced machine learning tools that can be applied to other animals in the future. This paper details a roadmap toward this goal based on currently existing technology and multidisciplinary scientific community effort. We outline the key elements required for the collection and processing of massive bioacoustic data of sperm whales, detecting their basic communication units and language-like higher-level structures, and validating these models through interactive playback experiments. The technological capabilities developed by such an undertaking are likely to yield cross-applications and advancements in broader communities investigating non-human communication and animal behavioral research.

Suicide is the 10th leading cause of death in the U.S (1999-2019). However, predicting when someone will attempt suicide has been nearly impossible. In the modern world, many individuals suffering from mental illness seek emotional support and advice on well-known and easily-accessible social media platforms such as Reddit. While prior artificial intelligence research has demonstrated the ability to extract valuable information from social media on suicidal thoughts and behaviors, these efforts have not considered both severity and temporality of risk. The insights made possible by access to such data have enormous clinical potential - most dramatically envisioned as a trigger to employ timely and targeted interventions (i.e., voluntary and involuntary psychiatric hospitalization) to save lives. In this work, we address this knowledge gap by developing deep learning algorithms to assess suicide risk in terms of severity and temporality from Reddit data based on the Columbia Suicide Severity Rating Scale (C-SSRS). In particular, we employ two deep learning approaches: time-variant and time-invariant modeling, for user-level suicide risk assessment, and evaluate their performance against a clinician-adjudicated gold standard Reddit corpus annotated based on the C-SSRS. Our results suggest that the time-variant approach outperforms the time-invariant method in the assessment of suicide-related ideations and supportive behaviors (AUC:0.78), while the time-invariant model performed better in predicting suicide-related behaviors and suicide attempt (AUC:0.64). The proposed approach can be integrated with clinical diagnostic interviews for improving suicide risk assessments.

Various robustness evaluation methodologies from different perspectives have been proposed for different natural language processing (NLP) tasks. These methods have often focused on either universal or task-specific generalization capabilities. In this work, we propose a multilingual robustness evaluation platform for NLP tasks (TextFlint) that incorporates universal text transformation, task-specific transformation, adversarial attack, subpopulation, and their combinations to provide comprehensive robustness analysis. TextFlint enables practitioners to automatically evaluate their models from all aspects or to customize their evaluations as desired with just a few lines of code. To guarantee user acceptability, all the text transformations are linguistically based, and we provide a human evaluation for each one. TextFlint generates complete analytical reports as well as targeted augmented data to address the shortcomings of the model's robustness. To validate TextFlint's utility, we performed large-scale empirical evaluations (over 67,000 evaluations) on state-of-the-art deep learning models, classic supervised methods, and real-world systems. Almost all models showed significant performance degradation, including a decline of more than 50% of BERT's prediction accuracy on tasks such as aspect-level sentiment classification, named entity recognition, and natural language inference. Therefore, we call for the robustness to be included in the model evaluation, so as to promote the healthy development of NLP technology.

Personal health libraries (PHLs) provide a single point of secure access to patients digital health data and enable the integration of knowledge stored in their digital health profiles with other sources of global knowledge. PHLs can help empower caregivers and health care providers to make informed decisions about patients health by understanding medical events in the context of their lives. This paper reports the implementation of a mobile health digital intervention that incorporates both digital health data stored in patients PHLs and other sources of contextual knowledge to deliver tailored recommendations for improving self-care behaviors in diabetic adults. We conducted a thematic assessment of patient functional and nonfunctional requirements that are missing from current EHRs based on evidence from the literature. We used the results to identify the technologies needed to address those requirements. We describe the technological infrastructures used to construct, manage, and integrate the types of knowledge stored in the PHL. We leverage the Social Linked Data (Solid) platform to design a fully decentralized and privacy-aware platform that supports interoperability and care integration. We provided an initial prototype design of a PHL and drafted a use case scenario that involves four actors to demonstrate how the proposed prototype can be used to address user requirements, including the construction and management of the PHL and its utilization for developing a mobile app that queries the knowledge stored and integrated into the PHL in a private and fully decentralized manner to provide better recommendations. The proposed PHL helps patients and their caregivers take a central role in making decisions regarding their health and equips their health care providers with informatics tools that support the collection and interpretation of the collected knowledge.

Increasing automation in the healthcare sector calls for a Hybrid Intelligence (HI) approach to closely study and design the collaboration of humans and autonomous machines. Ensuring that medical HI systems' decision-making is ethical is key. The use of Team Design Patterns (TDPs) can advance this goal by describing successful and reusable configurations of design problems in which decisions have a moral component, as well as through facilitating communication in multidisciplinary teams designing HI systems. For this research, TDPs were developed to describe a set of solutions for two design problems in a medical HI system: (1) mitigating harmful biases in machine learning algorithms and (2) sharing health and behavioral patient data with healthcare professionals and system developers. The Socio-Cognitive Engineering methodology was employed, integrating operational demands, human factors knowledge, and a technological analysis into a set of TDPs. A survey was created to assess the usability of the patterns on their understandability, effectiveness, and generalizability. The results showed that TDPs are a useful method to unambiguously describe solutions for diverse HI design problems with a moral component on varying abstraction levels, that are usable by a heterogeneous group of multidisciplinary researchers. Additionally, results indicated that the SCE approach and the developed questionnaire are suitable methods for creating and assessing TDPs. The study concludes with a set of proposed improvements to TDPs, including their integration with Interaction Design Patterns, the inclusion of several additional concepts, and a number of methodological improvements. Finally, the thesis recommends directions for future research.

Previous research in Explainable Artificial Intelligence (XAI) suggests that a main aim of explainability approaches is to satisfy specific interests, goals, expectations, needs, and demands regarding artificial systems (we call these stakeholders' desiderata) in a variety of contexts. However, the literature on XAI is vast, spreads out across multiple largely disconnected disciplines, and it often remains unclear how explainability approaches are supposed to achieve the goal of satisfying stakeholders' desiderata. This paper discusses the main classes of stakeholders calling for explainability of artificial systems and reviews their desiderata. We provide a model that explicitly spells out the main concepts and relations necessary to consider and investigate when evaluating, adjusting, choosing, and developing explainability approaches that aim to satisfy stakeholders' desiderata. This model can serve researchers from the variety of different disciplines involved in XAI as a common ground. It emphasizes where there is interdisciplinary potential in the evaluation and the development of explainability approaches.

This graduate textbook on machine learning tells a story of how patterns in data support predictions and consequential actions. Starting with the foundations of decision making, we cover representation, optimization, and generalization as the constituents of supervised learning. A chapter on datasets as benchmarks examines their histories and scientific bases. Self-contained introductions to causality, the practice of causal inference, sequential decision making, and reinforcement learning equip the reader with concepts and tools to reason about actions and their consequences. Throughout, the text discusses historical context and societal impact. We invite readers from all backgrounds; some experience with probability, calculus, and linear algebra suffices.

After challenging the validity of these assumptions in real-world applications, we propose ways to move forward when they are violated. First, we show that group fairness criteria purely based on statistical properties of observed data are fundamentally limited. Revisiting this limitation from a causal viewpoint we develop a more versatile conceptual framework, causal fairness criteria, and first algorithms to achieve them. We also provide tools to analyze how sensitive a believed-to-be causally fair algorithm is to misspecifications of the causal graph. Second, we overcome the assumption that sensitive data is readily available in practice. To this end we devise protocols based on secure multi-party computation to train, validate, and contest fair decision algorithms without requiring users to disclose their sensitive data or decision makers to disclose their models. Finally, we also accommodate the fact that outcome labels are often only observed when a certain decision has been made. We suggest a paradigm shift away from training predictive models towards directly learning decisions to relax the traditional assumption that labels can always be recorded. The main contribution of this thesis is the development of theoretically substantiated and practically feasible methods to move research on fair machine learning closer to real-world applications.

There is growing evidence showing the significant role of social determinant of health (SDOH) on a wide variety of health outcomes. In the era of artificial intelligence (AI), electronic health records (EHRs) have been widely used to conduct observational studies. However, how to make the best of SDOH information from EHRs is yet to be studied. In this paper, we systematically reviewed recently published papers and provided a methodology review of AI methods using the SDOH information in EHR data. A total of 1250 articles were retrieved from the literature between 2010 and 2020, and 74 papers were included in this review after abstract and full-text screening. We summarized these papers in terms of general characteristics (including publication years, venues, countries etc.), SDOH types, disease areas, study outcomes, AI methods to extract SDOH from EHRs and AI methods using SDOH for healthcare outcomes. Finally, we conclude this paper with discussion on the current trends, challenges, and future directions on using SDOH from EHRs.

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