We discuss an identification framework for noisy speech mixtures. A block-based generative model is formulated that explicitly incorporates the time-varying harmonic plus noise (H N) model for a number of latent sources observed through noisy convolutive mixtures. All parameters including the pitches of the source signals, the amplitudes and phases of the sources, the mixing filters and the noise statistics are estimated by maximum likelihood, using an EMalgorithm. Exact averaging over the hidden sources is obtained using the Kalman smoother. We show that pitch estimation and source separation can be performed simultaneously. The pitch estimates are compared to laryngograph (EGG) measurements. Artificial and real room mixtures are used to demonstrate the viability of the approach. Intelligible speech signals are re-synthesized from the estimated H N models.

We provide a method for mass meta-analysis in a neuroinformatics database containing stereotaxic Talairach coordinates from neuroimaging experiments. Database labels are used to group the individual experiments, e.g., according to cognitive function, and the consistent pattern of the experiments within the groups are determined.

Learning algorithms have enjoyed numerous successes in robotic control tasks. In problems with time-varying dynamics, online learning methods have also proved to be a powerful tool for automatically tracking and/or adapting to the changing circumstances. However, for safety-critical applications such as airplane flight, the adoption of these algorithms has been significantly hampered by their lack of safety, such as "stability," guarantees. Rather than trying to show difficult, a priori, stability guarantees for specific learning methods, in this paper we propose a method for "monitoring" the controllers suggested by the learning algorithm online, and rejecting controllers leading to instability. We prove that even if an arbitrary online learning method is used with our algorithm to control a linear dynamical system, the resulting system is stable.

Each of these problems can be solved using a spatial scan statistic (Kulldorff, 1997), where we compute the maximum of a likelihood ratio statistic over all spatial regions, and find the significance of this region by randomization. However, computing the scan statistic for all spatial regions is generally computationally infeasible, so we introduce a novel fast spatial scan algorithm, generalizing the 2D scan algorithm of (Neill and Moore, 2004) to arbitrary dimensions. Our new multidimensional multiresolution algorithm allows us to find spatial clusters up to 1400x faster than the naive spatial scan, without any loss of accuracy.

We do this by first defining a decomposition tree representation for G, which is closely related to the junction-tree representation for G. We then give an algorithm which uses this representation to compute the optimal H H. Gavril [2] and Tarjan [3] have used graph separation properties to solve several combinatorial optimization problems when the size of the minimal separators in the graph is bounded. We present an extension of this technique which applies to some important choices of H even when the size of the minimal separators of G are arbitrarily large. In particular, this applies to problems such as finding an optimal subgraphical model over a (k 1)-tree of a graphical model over a k-tree (for arbitrary k) and selecting an optimal subgraphical model with (a constant) d fewer edges with respect to KL-divergence can be solved in time polynomial in V (G) using this formulation.

A generative probabilistic model for objects in images is presented. An object consists of a constellation of features. Feature appearance and pose are modeled probabilistically. Scene images are generated by drawing a set of objects from a given database, with random clutter sprinkled on the remaining image surface.

A typical neuron in visual cortex receives most inputs from other cortical neurons with a roughly similar stimulus preference. Does this arrangement of inputs allow efficient readout of sensory information by the target cortical neuron? We address this issue by using simple modelling of neuronal population activity and information theoretic tools. We find that efficient synaptic information transmission requires that the tuning curve of the afferent neurons is approximately as wide as the spread of stimulus preferences of the afferent neurons reaching the target neuron. By meta analysis of neurophysiological data we found that this is the case for cortico-cortical inputs to neurons in visual cortex. We suggest that the organization of V1 cortico-cortical synaptic inputs allows optimal information transmission.

The standard approach to the classification of objects is to consider the examples as independent and identically distributed (iid). In many real world settings, however, this assumption is not valid, because a topographical relationship exists between the objects. In this contribution we consider the special case of image segmentation, where the objects are pixels and where the underlying topography is a 2D regular rectangular grid. We introduce a classification method which not only uses measured vectorial feature information but also the label configuration within a topographic neighborhood. Due to the resulting dependence between the labels of neighboring pixels, a collective classification of a set of pixels becomes necessary. We propose a new method called'Topographic Support Vector Machine' (TSVM), which is based on a topographic kernel and a self-consistent solution to the label assignment shown to be equivalent to a recurrent neural network. The performance of the algorithm is compared to a conventional SVM on a cell image segmentation task.

This paper provides a foundation for multi-task learning using reproducing kernel Hilbert spaces of vector-valued functions. In this setting, the kernel is a matrix-valued function. Some explicit examples will be described which go beyond our earlier results in [7]. In particular, we characterize classes of matrix-valued kernels which are linear and are of the dot product or the translation invariant type. We discuss how these kernels can be used to model relations between the tasks and present linear multi-task learning algorithms. Finally, we present a novel proof of the representer theorem for a minimizer of a regularization functional which is based on the notion of minimal norm interpolation.

We describe a way of using multiple different types of similarity relationship to learn a low-dimensional embedding of a dataset. Our method chooses different, possibly overlapping representations of similarity by individually reweighting the dimensions of a common underlying latent space. When applied to a single similarity relation that is based on Euclidean distances between the input data points, the method reduces to simple dimensionality reduction. If additional information is available about the dataset or about subsets of it, we can use this information to clean up or otherwise improve the embedding. We demonstrate the potential usefulness of this form of semi-supervised dimensionality reduction on some simple examples.