Many researchers have suggested that the psychological complexity of a concept is related to the length of its representation in a language of thought. As yet, however, there are few concrete proposals about the nature of this language. This paper makes one such proposal: the language of thought allows first order quantification (quantificationover objects) more readily than second-order quantification (quantification over features). To support this proposal we present behavioral results froma concept learning study inspired by the work of Shepard, Hovland and Jenkins. Humans can learn and think about many kinds of concepts, including natural kinds such as elephant and water and nominal kinds such as grandmother and prime number.

When used to guide decisions, linear regression analysis typically involves estimation of regression coefficients via ordinary least squares and their subsequent use to make decisions. When there are multiple response variables and features do not perfectly capture their relationships, it is beneficial to account for the decision objective when computing regression coefficients. Empirical optimization does so but sacrifices performance when features are well-chosen or training data are insufficient. We propose directed regression, an efficient algorithm that combines merits of ordinary least squares and empirical optimization. We demonstrate through a computational study that directed regression can generate significant performance gains over either alternative. We also develop a theory that motivates the algorithm.

We prove strong noise-tolerance properties of a potential-based boosting algorithm, similar to MadaBoost (Domingo and Watanabe, 2000) and SmoothBoost (Servedio, 2003). Our analysis is in the agnostic framework of Kearns, Schapire and Sellie (1994), giving polynomial-time guarantees in presence of arbitrary noise. A remarkable feature of our algorithm is that it can be implemented without reweighting examples, by randomly relabeling them instead. Our boosting theorem gives, as easy corollaries, alternative derivations of two recent non-trivial results in computational learning theory: agnostically learning decision trees (Gopalan et al, 2008) and agnostically learning halfspaces (Kalai et al, 2005). Experiments suggest that the algorithm performs similarly to Madaboost.

We consider the question of computing Maximum A Posteriori (MAP) assignment in an arbitrary pair-wise Markov Random Field (MRF). We present a randomized iterative algorithm based on simple local updates. The algorithm, starting with an arbitrary initial assignment, updates it in each iteration by first, picking a random node, then selecting an (appropriately chosen) random local neighborhood and optimizing over this local neighborhood. Somewhat surprisingly, we show that this algorithm finds a near optimal assignment within $2n\ln n$ iterations on average and with high probability for {\em any} $n$ node pair-wise MRF with {\em geometry} (i.e. MRF graph with polynomial growth) with the approximation error depending on (in a reasonable manner) the geometric growth rate of the graph and the average radius of the local neighborhood -- this allows for a graceful tradeoff between the complexity of the algorithm and the approximation error. Through extensive simulations, we show that our algorithm finds extremely good approximate solutions for various kinds of MRFs with geometry.

In this paper, we examine the generalization error of regularized distance metric learning. We show that with appropriate constraints, the generalization error of regularized distance metric learning could be independent from the dimensionality, making it suitable for handling high dimensional data. In addition, we present an efficient online learning algorithm for regularized distance metric learning. Our empirical studies with data classification and face recognition show that the proposed algorithm is (i) effective for distance metric learning when compared to the state-of-the-art methods, and (ii) efficient and robust for high dimensional data.

Motivated from real world problems, like object categorization, we study a particular mixed-norm regularization for Multiple Kernel Learning (MKL). It is assumed that the given set of kernels are grouped into distinct components where each component is crucial for the learning task at hand. The formulation hence employs $l_\infty$ regularization for promoting combinations at the component level and $l_1$ regularization for promoting sparsity among kernels in each component. While previous attempts have formulated this as a non-convex problem, the formulation given here is an instance of non-smooth convex optimization problem which admits an efficient Mirror-Descent (MD) based procedure. The MD procedure optimizes over product of simplexes, which is not a well-studied case in literature. Results on real-world datasets show that the new MKL formulation is well-suited for object categorization tasks and that the MD based algorithm outperforms state-of-the-art MKL solvers like \texttt{simpleMKL} in terms of computational effort.

The Minimum Description Length (MDL) principle selects the model that has the shortest code for data plus model. We show that for a countable class of models, MDL predictions are close to the true distribution in a strong sense. The result is completely general. No independence, ergodicity, stationarity, identifiability, or other assumption on the model class need to be made. More formally, we show that for any countable class of models, the distributions selected by MDL (or MAP) asymptotically predict (merge with) the true measure in the class in total variation distance.

Recent advances in neuroimaging techniques provide great potentials for effective diagnosis of Alzheimer's disease (AD), the most common form of dementia. Previous studies have shown that AD is closely related to the alternation in the functional brain network, i.e., the functional connectivity among different brain regions. In this paper, we consider the problem of learning functional brain connectivity from neuroimaging, which holds great promise for identifying image-based markers used to distinguish Normal Controls (NC), patients with Mild Cognitive Impairment (MCI), and patients with AD. More specifically, we study sparse inverse covariance estimation (SICE), also known as exploratory Gaussian graphical models, for brain connectivity modeling. In particular, we apply SICE to learn and analyze functional brain connectivity patterns from different subject groups, based on a key property of SICE, called the "monotone property" we established in this paper. Our experimental results on neuroimaging PET data of 42 AD, 116 MCI, and 67 NC subjects reveal several interesting connectivity patterns consistent with literature findings, and also some new patterns that can help the knowledge discovery of AD.

One of the central problems in neuroscience is reconstructing synaptic connectivity in neural circuits. Synapses onto a neuron can be probed by sequentially stimulating potentially pre-synaptic neurons while monitoring the membrane voltage of the post-synaptic neuron. Reconstructing a large neural circuit using such a "brute force" approach is rather time-consuming and inefficient because the connectivity in neural circuits is sparse. Instead, we propose to measure a post-synaptic neuron's voltage while stimulating sequentially random subsets of multiple potentially pre-synaptic neurons. To reconstruct these synaptic connections from the recorded voltage we apply a decoding algorithm recently developed for compressive sensing. Compared to the brute force approach, our method promises significant time savings that grow with the size of the circuit. We use computer simulations to find optimal stimulation parameters and explore the feasibility of our reconstruction method under realistic experimental conditions including noise and nonlinear synaptic integration. Multineuronal stimulationallows reconstructing synaptic connectivity just from the spiking activity of post-synaptic neurons, even when sub-threshold voltage is unavailable. By using calcium indicators, voltage-sensitive dyes, or multi-electrode arrays one could monitor activity of multiple postsynaptic neuronssimultaneously, thus mapping their synaptic inputs in parallel, potentially reconstructing a complete neural circuit.

Regularized risk minimization often involves non-smooth optimization, either because of the loss function (e.g., hinge loss) or the regularizer (e.g., $\ell_1$-regularizer). Gradient descent methods, though highly scalable and easy to implement, are known to converge slowly on these problems. In this paper, we develop novel accelerated gradient methods for stochastic optimization while still preserving their computational simplicity and scalability. The proposed algorithm, called SAGE (Stochastic Accelerated GradiEnt), exhibits fast convergence rates on stochastic optimization with both convex and strongly convex objectives. Experimental results show that SAGE is faster than recent (sub)gradient methods including FOLOS, SMIDAS and SCD. Moreover, SAGE can also be extended for online learning, resulting in a simple but powerful algorithm.