Technology
Analysis of Brain States from Multi-Region LFP Time-Series
Ulrich, Kyle R., Carlson, David E., Lian, Wenzhao, Borg, Jana S., Dzirasa, Kafui, Carin, Lawrence
The local field potential (LFP) is a source of information about the broad patterns of brain activity, and the frequencies present in these time-series measurements are often highly correlated between regions. It is believed that these regions may jointly constitute a ``brain state,'' relating to cognition and behavior. An infinite hidden Markov model (iHMM) is proposed to model the evolution of brain states, based on electrophysiological LFP data measured at multiple brain regions. A brain state influences the spectral content of each region in the measured LFP. A new state-dependent tensor factorization is employed across brain regions, and the spectral properties of the LFPs are characterized in terms of Gaussian processes (GPs). The LFPs are modeled as a mixture of GPs, with state- and region-dependent mixture weights, and with the spectral content of the data encoded in GP spectral mixture covariance kernels. The model is able to estimate the number of brain states and the number of mixture components in the mixture of GPs. A new variational Bayesian split-merge algorithm is employed for inference. The model infers state changes as a function of external covariates in two novel electrophysiological datasets, using LFP data recorded simultaneously from multiple brain regions in mice; the results are validated and interpreted by subject-matter experts.
Deep Joint Task Learning for Generic Object Extraction
Wang, Xiaolong, Zhang, Liliang, Lin, Liang, Liang, Zhujin, Zuo, Wangmeng
This paper investigates how to extract objects-of-interest without relying on hand-craft features and sliding windows approaches, that aims to jointly solve two sub-tasks: (i) rapidly localizing salient objects from images, and (ii) accurately segmenting the objects based on the localizations. We present a general joint task learning framework, in which each task (either object localization or object segmentation) is tackled via a multi-layer convolutional neural network, and the two networks work collaboratively to boost performance. In particular, we propose to incorporate latent variables bridging the two networks in a joint optimization manner. The first network directly predicts the positions and scales of salient objects from raw images, and the latent variables adjust the object localizations to feed the second network that produces pixelwise object masks. An EM-type method is then studied for the joint optimization, iterating with two steps: (i) by using the two networks, it estimates the latent variables by employing an MCMC-based sampling method; (ii) it optimizes the parameters of the two networks unitedly via back propagation, with the fixed latent variables. Extensive experiments demonstrate that our joint learning framework significantly outperforms other state-of-the-art approaches in both accuracy and efficiency (e.g., 1000 times faster than competing approaches).
Distributed Variational Inference in Sparse Gaussian Process Regression and Latent Variable Models
Gal, Yarin, Wilk, Mark van der, Rasmussen, Carl Edward
Carl E. Rasmussen Gaussian processes (GPs) are a powerful tool for probabilistic inference over functions. Theyhave been applied to both regression and nonlinear dimensionality reduction, and offer desirable properties such as uncertainty estimates, robustness to over-fitting, and principled ways for tuning hyper-parameters. However the scalability of these models to big datasets remains an active topic of research. We introduce a novel re-parametrisation of variational inference for sparse GP regression and latent variable models that allows for an efficient distributed algorithm. Thisis done by exploiting the decoupling of the data given the inducing points to reformulate the evidence lower bound in a Map-Reduce setting. We show that the inference scales well with data and computational resources, while preserving a balanced distribution of the load among the nodes. We further demonstrate the utility in scaling Gaussian processes to big data. We show that GP performance improves with increasing amounts of data in regression (on flight data with 2 million records) and latent variable modelling (on MNIST). The results show that GPs perform better than many common models often used for big data.
On the Information Theoretic Limits of Learning Ising Models
Tandon, Rashish, Shanmugam, Karthikeyan, Ravikumar, Pradeep K., Dimakis, Alexandros G.
We provide a general framework for computing lower-bounds on the sample complexity of recovering the underlying graphs of Ising models, given i.i.d. samples. While there have been recent results for specific graph classes, these involve fairly extensive technical arguments that are specialized to each specific graph class. In contrast, we isolate two key graph-structural ingredients that can then be used to specify sample complexity lower-bounds. Presence of these structural properties makes the graph class hard to learn. We derive corollaries of our main result that not only recover existing recent results, but also provide lower bounds for novel graph classes not considered previously. We also extend our framework to the random graph setting and derive corollaries for Erdos-Renyi graphs in a certain dense setting.
Spectral Clustering of graphs with the Bethe Hessian
Saade, Alaa, Krzakala, Florent, Zdeborovรก, Lenka
Spectral clustering is a standard approach to label nodes on a graph by studying the (largest or lowest) eigenvalues of a symmetric real matrix such as e.g. the adjacency or the Laplacian. Recently, it has been argued that using instead a more complicated, non-symmetric and higher dimensional operator, related to the non-backtracking walk on the graph, leads to improved performance in detecting clusters, and even to optimal performance for the stochastic block model. Here, we propose to use instead a simpler object, a symmetric real matrix known as the Bethe Hessian operator, or deformed Laplacian. We show that this approach combines the performances of the non-backtracking operator, thus detecting clusters all the way down to the theoretical limit in the stochastic block model, with the computational, theoretical and memory advantages of real symmetric matrices. Clustering a graph into groups or functional modules (sometimes called communities) is a central task in many fields ranging from machine learning to biology. A common benchmark for this problem is to consider graphs generated by the stochastic block model (SBM) [7, 22].
Distributed Bayesian Posterior Sampling via Moment Sharing
Xu, Minjie, Lakshminarayanan, Balaji, Teh, Yee Whye, Zhu, Jun, Zhang, Bo
We propose a distributed Markov chain Monte Carlo (MCMC) inference algorithm for large scale Bayesian posterior simulation. We assume that the dataset is partitioned and stored across nodes of a cluster. Our procedure involves an independent MCMC posterior sampler at each node based on its local partition of the data. Moment statistics of the local posteriors are collected from each sampler and propagated across the cluster using expectation propagation message passing with low communication costs. The moment sharing scheme improves posterior estimation quality by enforcing agreement among the samplers. We demonstrate the speed and inference quality of our method with empirical studies on Bayesian logistic regression and sparse linear regression with a spike-and-slab prior.
SerialRank: Spectral Ranking using Seriation
Fogel, Fajwel, d', Aspremont, Alexandre, Vojnovic, Milan
We describe a seriation algorithm for ranking a set of n items given pairwise comparisons between these items. Intuitively, the algorithm assigns similar rankings to items that compare similarly with all others. It does so by constructing a similarity matrix from pairwise comparisons, using seriation methods to reorder this matrix and construct a ranking. We first show that this spectral seriation algorithm recovers the true ranking when all pairwise comparisons are observed and consistent with a total order. We then show that ranking reconstruction is still exact even when some pairwise comparisons are corrupted or missing, and that seriation based spectral ranking is more robust to noise than other scoring methods. An additional benefit of the seriation formulation is that it allows us to solve semi-supervised ranking problems. Experiments on both synthetic and real datasets demonstrate that seriation based spectral ranking achieves competitive and in some cases superior performance compared to classical ranking methods.
Expectation-Maximization for Learning Determinantal Point Processes
Gillenwater, Jennifer A., Kulesza, Alex, Fox, Emily, Taskar, Ben
A determinantal point process (DPP) is a probabilistic model of set diversity compactly parameterized by a positive semi-definite kernel matrix. To fit a DPP to a given task, we would like to learn the entries of its kernel matrix by maximizing the log-likelihood of the available data. However, log-likelihood is non-convex in the entries of the kernel matrix, and this learning problem is conjectured to be NP-hard. Thus, previous work has instead focused on more restricted convex learning settings: learning only a single weight for each row of the kernel matrix, or learning weights for a linear combination of DPPs with fixed kernel matrices. In this work we propose a novel algorithm for learning the full kernel matrix. By changing the kernel parameterization from matrix entries to eigenvalues and eigenvectors, and then lower-bounding the likelihood in the manner of expectation-maximization algorithms, we obtain an effective optimization procedure. We test our method on a real-world product recommendation task, and achieve relative gains of up to 16.5% in test log-likelihood compared to the naive approach of maximizing likelihood by projected gradient ascent on the entries of the kernel matrix.
Log-Hilbert-Schmidt metric between positive definite operators on Hilbert spaces
Quang, Minh Ha, Biagio, Marco San, Murino, Vittorio
This paper introduces a novel mathematical and computational framework, namely {\it Log-Hilbert-Schmidt metric} between positive definite operators on a Hilbert space. This is a generalization of the Log-Euclidean metric on the Riemannian manifold of positive definite matrices to the infinite-dimensional setting. The general framework is applied in particular to compute distances between covariance operators on a Reproducing Kernel Hilbert Space (RKHS), for which we obtain explicit formulas via the corresponding Gram matrices. Empirically, we apply our formulation to the task of multi-category image classification, where each image is represented by an infinite-dimensional RKHS covariance operator. On several challenging datasets, our method significantly outperforms approaches based on covariance matrices computed directly on the original input features, including those using the Log-Euclidean metric, Stein and Jeffreys divergences, achieving new state of the art results.
Subspace Embeddings for the Polynomial Kernel
Avron, Haim, Nguyen, Huy, Woodruff, David
Sketching is a powerful dimensionality reduction tool for accelerating statistical learning algorithms. However, its applicability has been limited to a certain extent since the crucial ingredient, the so-called oblivious subspace embedding, can only be applied to data spaces with an explicit representation as the column span or row span of a matrix, while in many settings learning is done in a high-dimensional space implicitly defined by the data matrix via a kernel transformation. We propose the first {\em fast} oblivious subspace embeddings that are able to embed a space induced by a non-linear kernel {\em without} explicitly mapping the data to the high-dimensional space. In particular, we propose an embedding for mappings induced by the polynomial kernel. Using the subspace embeddings, we obtain the fastest known algorithms for computing an implicit low rank approximation of the higher-dimension mapping of the data matrix, and for computing an approximate kernel PCA of the data, as well as doing approximate kernel principal component regression.