Science Space Deep Space Space Telescope Put your name aboard NASA's Nancy Grace Roman Space Telescope The next generation space observatory is scheduled to launch in August. More information Adding us as a Preferred Source in Google by using this link indicates that you would like to see more of our content in Google News results. The NASA observatory was designed to settle essential questions in the areas of dark energy, exoplanets, and infrared astrophysics. Roman's barrel-like shape will help block out unwanted light from the sun, Earth, and moon, and the spacecraft's distant location will help keep the instruments cool. Breakthroughs, discoveries, and DIY tips sent six days a week.

Data integration approaches are increasingly used to enhance the efficiency and generalizability of studies. However, a key limitation of these methods is the assumption that outcome measures are identical across datasets - an assumption that often does not hold in practice. Consider the following opioid use disorder (OUD) studies: the XBOT trial and the POAT study, both evaluating the effect of medications for OUD on withdrawal symptom severity (not the primary outcome of either trial). While XBOT measures withdrawal severity using the subjective opiate withdrawal scale, POAT uses the clinical opiate withdrawal scale. We analyze this realistic yet challenging setting where outcome measures differ across studies and where neither study records both types of outcomes. Our paper studies whether and when integrating studies with disparate outcome measures leads to efficiency gains.

Don't be fooled by the compact size of this soundbar. It's a solid option for smaller TVs or spaces without having to sacrifice sound quality. Acoustic music sounds loud and distinct. Some music sounds washed out and muddy. Living in a small space has some challenges, but poor cinematic sound doesn't need to be one of them.

Large Language Models (LLMs) continue to exhibit vulnerabilities despite deliberate safety alignment efforts, posing significant risks to users and society. To safeguard against the risk of policy-violating content, system-level moderation via external guard models--designed to monitor LLM inputs and outputs and block potentially harmful content--has emerged as a prevalent mitigation strategy. Existing approaches of training guard models rely heavily on extensive human curated datasets and struggle with out-of-distribution threats, such as emerging harmful categories or jailbreak attacks. To address these limitations, we propose RSafe, an adaptive reasoning-based safeguard that conducts guided safety reasoning to provide robust protection within the scope of specified safety policies. RSafe operates in two stages: (1) guided reasoning, where it analyzes safety risks of input content through policy-guided step-by-step reasoning, and (2) reinforced alignment, where rule-based RL optimizes its reasoning paths to align with accurate safety prediction.

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Large language models (LLMs), despite their impressive performance across a wide range of tasks, often struggle to balance two competing objectives in openended text generation: fostering diversity and creativity while preserving logical coherence. Existing truncated sampling techniques, including temperature scaling, top-p (nucleus) sampling, and min-p sampling, aim to manage this trade-off.

This paper addresses the problem of learning avoidance behavior within the context of offline imitation learning. In contrast to conventional methodologies that prioritize the replication of expert or near-expert demonstrations, our work investigates a setting where expert (or desirable) data is absent, and the objective is to learn to eschew undesirable actions by leveraging demonstrations of such behavior (i.e., learning from negative examples). To address this challenge, we propose a novel training objective grounded in the maximum entropy principle. We further characterize the fundamental properties of this objective function, reformulating the learning process as a cooperative inverse Q-learning task. Moreover, we introduce an efficient strategy for the integration of unlabeled data (i.e., data of indeterminate quality) to facilitate unbiased and practical offline training. The efficacy of our method is evaluated across standard benchmark environments, where it consistently outperforms state-of-the-art baselines.

Designing protein sequences that fold into a target 3D structure--known as protein inverse folding--is a fundamental challenge in protein engineering. While recent deep learning methods have achieved impressive performance by recovering native sequences, they often overlook the one-to-many nature of the problem: multiple diverse sequences can fold into the same structure.

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