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Appendix Reinforcement Learning Baselines

Neural Information Processing Systems

DrQ: This model-free, off-policy reinforcement learning algorithm, is based on Soft Actor-Critic (SAC) [19]. DrQ enhances training stability via applying data augmentation to regularize the Q value of state-action pairs. The key of DrQ is to promote similarity between augmented state-action pairs. The Q-regularization technique is shown in Eq 1, where K is the number of samples, T is the collection of augmentation. Q(f (s,ฮฝk),ak) where ฮฝk T and ak ฯ€( | f (s,ฮฝk)) (1) DrQ-v2: An improved version of DrQ. DrQ-v2 fuses essential elements from the DDPG algorithm with data augmentation to strengthen visual RL agents' performance. DrQ-v2 also incorporates techniques such as n-step return and target critic, leading to commendable results in most of the medium and hard level DM-Control tasks. The auxiliary contrastive loss (Eq 3) allows the agent to obtain better image representation during training, thus mitigating the optimization difficulty under high-dimensional inputs.




Noisy Recurrent Neural Networks

Neural Information Processing Systems

We provide a general framework for studying recurrent neural networks (RNNs) trained by injecting noise into hidden states. Specifically, we consider RNNs that can be viewed as discretizations of stochastic differential equations driven by input data. This framework allows us to study the implicit regularization effect of general noise injection schemes by deriving an approximate explicit regularizer in the small noise regime. We find that, under reasonable assumptions, this implicit regularization promotes flatter minima; it biases towards models with more stable dynamics; and, in classification tasks, it favors models with larger classification margin. Sufficient conditions for global stability are obtained, highlighting the phenomenon of stochastic stabilization, where noise injection can improve stability during training. Our theory is supported by empirical results which demonstrate that the RNNs have improved robustness with respect to various input perturbations.





291d43c696d8c3704cdbe0a72ade5f6c-Supplemental.pdf

Neural Information Processing Systems

A.1 Broader impact Our work introduces a general method for unsupervised 3D segmentation that can be used for any 3D voxel-grid data. This line of work is especially useful for analyzing biomedical data, as many different types of biomedical data are in volumetric form and lack the ground truth annotations required for fully-or semi-supervised segmentation. For example, we may wish to study diseased tissue but do not have sufficient understanding to ensure that unexplored features of interests are labelled in training data. We illustrate the potential of our proposed approach for scientific discovery applications using our example of cryo-ET data in the Appendix. The discovered features can now be analyzed for their chemical identities and functions, in diseased vs. healthy cells.