Magnification shift is a major obstacle to robust histopathology classification, because models trained on one imaging scale often generalize poorly to another. Here, we evaluated this problem on the BreaKHis dataset using a strict patient-disjoint leave-one-magnification-out protocol, comparing supervised baseline, baseline augmented with DCGAN-generated patches, and a gradient-reversal domain-general model designed to preserve discriminative information while suppressing magnification-specific variation. Across held-out magnifications, the domain-general model achieved the strongest overall discrimination and its clearest gain was observed when 200X was held out. By contrast, GAN augmentation produced inconsistent effects, improving some folds but degrading others, particularly at 400X. The domain-general model also yielded the lowest Brier score at 0.063 vs 0.089 at baseline. Sparse embedding analysis further revealed that domain-general training reduced average signature size more than three-fold (306 versus 1,074 dimensions) while preserving equivalent predictive performance (AUC: 0.967 vs 0.965; F1: 0.930 vs 0.931). It also increased cross-fold signature reproducibility from near-zero Jaccard overlap in the baseline to 0.99 between the 100X and 200X folds. These findings show that calibrated, compact, and transferable representations can be learned without added architectural complexity, with clear implications for the reliable deployment of computational pathology models across heterogeneous acquisition settings.

Label noise presents a fundamental challenge in modern machine learning, especially when large-scale datasets are generated via automated processes. An increasingly common and important data paradigm, particularly in domains like medical imaging, involves learning from a large dataset with coarse, noisy labels supplemented by a small, expert-verified, clean dataset. This setting constitutes a typical information transfer and fusion problem. However, the significant distribution shift between the noisy and clean data violates the core overall parametric similarity assumptions of existing statistical transfer learning methods, while their reliance on parametric models is ill-suited for complex data like images. To address these limitations, this paper develops a generic model-agnostic nonparametric framework for classification with label noise, which applies to a broad class of classifiers. Our approach leverages the small clean dataset to ``purify'' the large noisy one and carefully manages the remaining ambiguous samples. This framework is underpinned by a rigorous statistical theory. Its empirical performance is demonstrated through simulations and a real-world application to medical image analysis for pneumonia diagnosis.

Training language models via reinforcement learning often relies on imperfect proxy rewards, since ground truth rewards that precisely define the intended behavior are rarely available. Standard metrics for assessing the quality of proxy rewards, such as ranking accuracy, treat incorrect rewards as strictly harmful. In this work, however, we highlight that not all deviations from the ground truth are equal. By theoretically analyzing which outputs attract probability during policy gradient optimization, we categorize reward errors according to their effect on the increase in ground truth reward. The analysis establishes that reward errors, though conventionally viewed as harmful, can also be benign or even beneficial by preventing the policy from stalling around outputs with mediocre ground truth reward. We then present two practical implications of our theory. First, for reinforcement learning from human feedback (RLHF), we develop reward model evaluation metrics that account for the harmfulness of reward errors. Compared to standard ranking accuracy, these metrics typically correlate better with the performance of a language model after RLHF, yet gaps remain in robustly evaluating reward models. Second, we provide insights for reward design in settings with verifiable rewards. A key theme underlying our results is that the effectiveness of a proxy reward function depends heavily on its interaction with the initial policy and learning algorithm.

Identity teacher forcing (ITF) enables stable training of deterministic recurrent surrogates for chaotic dynamical systems and has been highly effective for dynamical systems reconstruction (DSR) with recurrent neural networks (RNNs), including interpretable almost-linear RNNs (AL-RNNs). However, as an intervention-based prediction loss (and thus a generalized Bayes update), teacher forcing need not match the free-running model's marginal likelihood geometry. We compare the objective-induced curvatures of ITF and marginal likelihood in a probabilistic switching augmentation of AL-RNNs, estimating ambiguity-aware observed information via Louis' identity. In the switching setting studied here, conditioning on a single forced regime path (as ITF does) inflates curvature, while marginal likelihood curvature is reduced by a missing-information correction when multiple switching explanations remain plausible. In Lorenz-63 experiments, windowed evidence fine-tuning improves held-out evidence but can degrade dynamical quantities of interest (QoIs) relative to ITF-pretrained models.

"Never talk about goblins, gremlins, raccoons, trolls, ogres, pigeons, or other animals or creatures unless it is absolutely and unambiguously relevant," reads OpenAI's coding agent instructions. OpenAI has a goblin problem. Instructions designed to guide the behavior of the company's latest model as it writes code have been revealed to include a line, repeated several times, that specifically forbids it from randomly mentioning an assortment of mythical and real creatures. "Never talk about goblins, gremlins, raccoons, trolls, ogres, pigeons, or other animals or creatures unless it is absolutely and unambiguously relevant to the user's query," read instructions in Codex CLI, a command-line tool for using AI to generate code. It is unclear why OpenAI felt compelled to spell this out for Codex --or indeed why its models might want to discuss goblins or pigeons in the first place.

As the field of automated machine learning (AutoML) advances, it becomes increasingly important to incorporate domain knowledge into these systems. We present an approach for doing so by harnessing the power of large language models (LLMs). Specifically, we introduce Context-Aware Automated Feature Engineering (CAAFE), a feature engineering method for tabular datasets that utilizes an LLM to iteratively generate additional semantically meaningful features for tabular datasets based on the description of the dataset. The method produces both Python code for creating new features and explanations for the utility of the generated features. Despite being methodologically simple, CAAFE improves performance on 11 out of 14 datasets - boosting mean ROCAUC performance from 0.798 to 0.822 across all dataset - similar to the improvement achieved by using a random forest instead of logistic regression on our datasets. Furthermore, CAAFE is interpretable by providing a textual explanation for each generated feature. CAAFE paves the way for more extensive semi-automation in data science tasks and emphasizes the significance of context-aware solutions that can extend the scope of AutoML systems to semantic AutoML. We release our code, a simple demo and a python package.

Policy network parameter sharing is a commonly used technique in advanced deep multi-agent reinforcement learning (MARL) algorithms to improve learning efficiency by reducing the number of policy parameters and sharing experiences among agents. Nevertheless, agents that share the policy parameters tend to learn similar behaviors. To encourage multi-agent diversity, prior works typically maximize the mutual information between trajectories and agent identities using variational inference. However, this category of methods easily leads to inefficient exploration due to limited trajectory visitations. To resolve this limitation, inspired by the learning of pre-trained models, in this paper, we propose a novel Contrastive Trajectory Representation (CTR) method based on learning distinguishable trajectory representations to encourage multi-agent diversity.

The trial between the CEOs makes the AI boom seem sordid and small. Elon Musk and Sam Altman are two of the most influential people in Silicon Valley, if not the world. Between the two of them, Musk and Altman run technology companies worth many trillions of dollars that promise to reshape civilization. But this morning, both sat under fluorescent lights in a courthouse in downtown Oakland, suffering through all manner of technical glitches as their respective attorneys kicked off the long-awaited trial in . As Steven Molo, a lawyer for Musk, began his opening argument, confused looks swept the courtroom.

Self-supervised training methods for transformers have demonstrated remarkable performance across various domains. Previous transformer-based models, such as masked autoencoders (MAE), typically utilize a single normalization layer for both the class token [CLS] and the tokens. We propose in this paper a new yet simple normalization method that separately normalizes embedding vectors respectively corresponding to normal tokens and the [CLS]token, in order to better capture their distinct characteristics and enhance downstream task performance. Our empirical study shows that the [CLS]embeddings learned with our separate normalization layer better encode the global contextual information and are distributed more uniformly in its anisotropic space. When the conventional normalization layer is replaced with a separate normalization layer, we observe an average 2.7% performance improvement in learning tasks from the image, natural language, and graph domains.