Bayesian Inference
PAC-Bayes Learning of Conjunctions and Classification of Gene-Expression Data
We propose a "soft greedy" learning algorithm for building small conjunctions of simple threshold functions, called rays, defined on single real-valued attributes. We also propose a PAC-Bayes risk bound which is minimized for classifiers achieving a nontrivial tradeoff between sparsity (the number of rays used) and the magnitude of the separating margin of each ray. Finally, we test the soft greedy algorithm on four DNA micro-array data sets.
Semi-supervised Learning with Penalized Probabilistic Clustering
While clustering is usually an unsupervised operation, there are circumstances in which we believe (with varying degrees of certainty) that items A and B should be assigned to the same cluster, while items A and C should not. We would like such pairwise relations to influence cluster assignments of out-of-sample data in a manner consistent with the prior knowledge expressed in the training set. Our starting point is probabilistic clustering based on Gaussian mixture models (GMM) of the data distribution. We express clustering preferences in the prior distribution over assignments of data points to clusters. This prior penalizes cluster assignments according to the degree with which they violate the preferences. We fit the model parameters with EM. Experiments on a variety of data sets show that PPC can consistently improve clustering results.
Maximum Likelihood Estimation of Intrinsic Dimension
Levina, Elizaveta, Bickel, Peter J.
We propose a new method for estimating intrinsic dimension of a dataset derived by applying the principle of maximum likelihood to the distances between close neighbors. We derive the estimator by a Poisson process approximation, assess its bias and variance theoretically and by simulations, and apply it to a number of simulated and real datasets. We also show it has the best overall performance compared with two other intrinsic dimension estimators.
Rate- and Phase-coded Autoassociative Memory
Areas of the brain involved in various forms of memory exhibit patterns of neural activity quite unlike those in canonical computational models. We show how to use well-founded Bayesian probabilistic autoassociative recall to derive biologically reasonable neuronal dynamics in recurrently coupled models, together with appropriate values for parameters such as the membrane time constant and inhibition. We explicitly treat two cases. One arises from a standard Hebbian learning rule, and involves activity patterns that are coded by graded firing rates. The other arises from a spike timing dependent learning rule, and involves patterns coded by the phase of spike times relative to a coherent local field potential oscillation. Our model offers a new and more complete understanding of how neural dynamics may support autoassociation.
Joint MRI Bias Removal Using Entropy Minimization Across Images
Learned-miller, Erik G., Ahammad, Parvez
The correction of bias in magnetic resonance images is an important problem in medical image processing. Most previous approaches have used a maximum likelihood method to increase the likelihood of the pixels in a single image by adaptively estimating a correction to the unknown image bias field. The pixel likelihoods are defined either in terms of a preexisting tissue model, or non-parametrically in terms of the image's own pixel values. In both cases, the specific location of a pixel in the image is not used to calculate the likelihoods. We suggest a new approach in which we simultaneously eliminate the bias from a set of images of the same anatomy, but from different patients. We use the statistics from the same location across different images, rather than within an image, to eliminate bias fields from all of the images simultaneously. The method builds a "multi-resolution" nonparametric tissue model conditioned on image location while eliminating the bias fields associated with the original image set.
Bayesian inference in spiking neurons
We propose a new interpretation of spiking neurons as Bayesian integrators accumulating evidence over time about events in the external world or the body, and communicating to other neurons their certainties about these events. In this model, spikes signal the occurrence of new information, i.e. what cannot be predicted from the past activity. As a result, firing statistics are close to Poisson, albeit providing a deterministic representation of probabilities. We proceed to develop a theory of Bayesian inference in spiking neural networks, recurrent interactions implementing a variant of belief propagation. Many perceptual and motor tasks performed by the central nervous system are probabilistic, and can be described in a Bayesian framework [4, 3].
A Machine Learning Approach to Conjoint Analysis
Chapelle, Olivier, Harchaoui, Zaïd
Choice-based conjoint analysis builds models of consumer preferences over products with answers gathered in questionnaires. Our main goal is to bring tools from the machine learning community to solve this problem more efficiently. Thus, we propose two algorithms to quickly and accurately estimate consumer preferences.
Spike Sorting: Bayesian Clustering of Non-Stationary Data
Bar-hillel, Aharon, Spiro, Adam, Stark, Eran
Spike sorting involves clustering spike trains recorded by a microelectrode according to the source neuron. It is a complicated problem, which requires a lot of human labor, partly due to the non-stationary nature of the data. We propose an automated technique for the clustering of non-stationary Gaussian sources in a Bayesian framework. At a first search stage, data is divided into short time frames and candidate descriptions of the data as a mixture of Gaussians are computed for each frame. At a second stage transition probabilities between candidate mixtures are computed, and a globally optimal clustering is found as the MAP solution of the resulting probabilistic model. Transition probabilities are computed using local stationarity assumptions and are based on a Gaussian version of the Jensen-Shannon divergence. The method was applied to several recordings. The performance appeared almost indistinguishable from humans in a wide range of scenarios, including movement, merges, and splits of clusters.
A Probabilistic Model for Online Document Clustering with Application to Novelty Detection
Zhang, Jian, Ghahramani, Zoubin, Yang, Yiming
In this paper we propose a probabilistic model for online document clustering. We use nonparametric Dirichlet process prior to model the growing number of clusters, and use a prior of general English language model as the base distribution to handle the generation of novel clusters. Furthermore, cluster uncertainty is modeled with a Bayesian Dirichletmultinomial distribution. We use empirical Bayes method to estimate hyperparameters based on a historical dataset. Our probabilistic model is applied to the novelty detection task in Topic Detection and Tracking (TDT) and compared with existing approaches in the literature.