Privacy preserving mechanisms such as differential privacy inject additional randomness in the form of noise in the data, beyond the sampling mechanism. Ignoring this additional noise can lead to inaccurate and invalid inferences. In this paper, we incorporate the privacy mechanism explicitly into the likelihood function by treating the original data as missing, with an end goal of estimating posterior distributions over model parameters. This leads to a principled way of performing valid statistical inference using private data, however, the corresponding likelihoods are intractable. In this paper, we derive fast and accurate variational approximations to tackle such intractable likelihoods that arise due to privacy. We focus on estimating posterior distributions of parameters of the naive Bayes log-linear model, where the sufficient statistics of this model are shared using a differentially private interface. Using a simulation study, we show that the posterior approximations outperform the naive method of ignoring the noise addition mechanism.

We propose Kernel Hamiltonian Monte Carlo (KMC), a gradient-free adaptive MCMC algorithm based on Hamiltonian Monte Carlo (HMC). On target densities where classical HMC is not an option due to intractable gradients, KMC adaptively learns the target's gradient structure by fitting an exponential family model in a Reproducing Kernel Hilbert Space. Computational costs are reduced by two novel efficient approximations to this gradient. While being asymptotically exact, KMC mimics HMC in terms of sampling efficiency, and offers substantial mixing improvements over state-of-the-art gradient free samplers. We support our claims with experimental studies on both toy and real-world applications, including Approximate Bayesian Computation and exact-approximate MCMC.

We derive a statistical model for estimation of a dendrogram from single linkage hierarchical clustering (SLHC) that takes account of uncertainty through noise or corruption in the measurements of separation of data. Our focus is on just the estimation of the hierarchy of partitions afforded by the dendrogram, rather than the heights in the latter. The concept of estimating this "dendrogram structure'' is introduced, and an approximate maximum likelihood estimator (MLE) for the dendrogram structure is described. These ideas are illustrated by a simple Monte Carlo simulation that, at least for small data sets, suggests the method outperforms SLHC in the presence of noise.

Gaussian process is a theoretically appealing model for nonparametric analysis, but its computational cumbersomeness hinders its use in large scale and the existing reduced-rank solutions are usually heuristic. In this work, we propose a novel construction of Gaussian process as a projection from fixed discrete frequencies to any continuous location. This leads to a valid stochastic process that has a theoretic support with the reduced rank in the spectral density, as well as a high-speed computing algorithm. Our method provides accurate estimates for the covariance parameters and concise form of predictive distribution for spatial prediction. For non-stationary data, we adopt the mixture framework with a customized spectral dependency structure. This enables clustering based on local stationarity, while maintains the joint Gaussianness. Our work is directly applicable in solving some of the challenges in the spatial data, such as large scale computation, anisotropic covariance, spatio-temporal modeling, etc. We illustrate the uses of the model via simulations and an application on a massive dataset.

We develop parallel predictive entropy search (PPES), a novel algorithm for Bayesian optimization of expensive black-box objective functions. At each iteration, PPES aims to select a batch of points which will maximize the information gain about the global maximizer of the objective. Well known strategies exist for suggesting a single evaluation point based on previous observations, while far fewer are known for selecting batches of points to evaluate in parallel. The few batch selection schemes that have been studied all resort to greedy methods to compute an optimal batch. To the best of our knowledge, PPES is the first non-greedy batch Bayesian optimization strategy. We demonstrate the benefit of this approach in optimization performance on both synthetic and real world applications, including problems in machine learning, rocket science and robotics.

In this paper we review the concepts of Bayesian evidence and Bayes factors, also known as log odds ratios, and their application to model selection. The theory is presented along with a discussion of analytic, approximate and numerical techniques. Specific attention is paid to the Laplace approximation, variational Bayes, importance sampling, thermodynamic integration, and nested sampling and its recent variants. Analogies to statistical physics, from which many of these techniques originate, are discussed in order to provide readers with deeper insights that may lead to new techniques. The utility of Bayesian model testing in the domain sciences is demonstrated by presenting four specific practical examples considered within the context of signal processing in the areas of signal detection, sensor characterization, scientific model selection and molecular force characterization.

A fundamental task in machine learning and related fields is to perform inference on Bayesian networks. Since exact inference takes exponential time in general, a variety of approximate methods are used. Gibbs sampling is one of the most accurate approaches and provides unbiased samples from the posterior but it has historically been too expensive for large models. In this paper, we present an optimized, parallel Gibbs sampler augmented with state replication (SAME or State Augmented Marginal Estimation) to decrease convergence time. We find that SAME can improve the quality of parameter estimates while accelerating convergence. Experiments on both synthetic and real data show that our Gibbs sampler is substantially faster than the state of the art sampler, JAGS, without sacrificing accuracy. Our ultimate objective is to introduce the Gibbs sampler to researchers in many fields to expand their range of feasible inference problems.

Expectation propagation (EP) is a deterministic approximation algorithm that is often used to perform approximate Bayesian parameter learning. EP approximates the full intractable posterior distribution through a set of local approximations that are iteratively refined for each datapoint. EP can offer analytic and computational advantages over other approximations, such as Variational Inference (VI), and is the method of choice for a number of models. The local nature of EP appears to make it an ideal candidate for performing Bayesian learning on large models in large-scale dataset settings. However, EP has a crucial limitation in this context: the number of approximating factors needs to increase with the number of data-points, N, which often entails a prohibitively large memory overhead. This paper presents an extension to EP, called stochastic expectation propagation (SEP), that maintains a global posterior approximation (like VI) but updates it in a local way (like EP). Experiments on a number of canonical learning problems using synthetic and real-world datasets indicate that SEP performs almost as well as full EP, but reduces the memory consumption by a factor of $N$. SEP is therefore ideally suited to performing approximate Bayesian learning in the large model, large dataset setting.

We address some computational issues that may hinder the use of AMP chain graphs in practice. Specifically, we show how a discrete probability distribution that satisfies all the independencies represented by an AMP chain graph factorizes according to it. We show how this factorization makes it possible to perform inference and parameter learning efficiently, by adapting existing algorithms for Markov and Bayesian networks. Finally, we turn our attention to another issue that may hinder the use of AMP CGs, namely the lack of an intuitive interpretation of their edges. We provide one such interpretation.

Pseudo-marginal Metropolis-Hastings (pmMH) is a powerful method for Bayesian inference in models where the posterior distribution is analytical intractable or computationally costly to evaluate directly. It operates by introducing additional auxiliary variables into the model and form an extended target distribution, which then can be evaluated point-wise. In many cases, the standard Metropolis-Hastings is then applied to sample from the extended target and the sought posterior can be obtained by marginalisation. However, in some implementations this approach suffers from poor mixing as the auxiliary variables are sampled from an independent proposal. We propose a modification to the pmMH algorithm in which a Crank-Nicolson (CN) proposal is used instead. This results in that we introduce a positive correlation in the auxiliary variables. We investigate how to tune the CN proposal and its impact on the mixing of the resulting pmMH sampler. The conclusion is that the proposed modification can have a beneficial effect on both the mixing of the Markov chain and the computational cost for each iteration of the pmMH algorithm.