"Search is a problem-solving technique that systematically explores a space of problem states, i.e., successive and alternative stages in the problem-solving process. Examples of problem states might include the different board configurations in a game or intermediate steps in a reasoning process. This space of alternative solutions is then searched to find an answer. Newell and Simon (1976) have argued that this is the essential basis of human problem solving. Indeed, when a chess player examines the effects of different moves or a doctor considers a number of alternative diagnoses, they are searching among alternatives." – from Section 1.2 of Chapter One of George F. Luger's textbook, Artificial Intelligence: Structures and Strategies for Complex Problem Solving, 5th Edition (Addison-Wesley; 2005).
Furthermore, we explore the potential of language models in generating co-crystals. Finally, we present numerous previously unknown co-crystals predicted by GEM-CODE and discuss its potential in accelerating drug development.
We provide more information on AIPS' deductive engine and the training process for the value network. To highlight the reasoning ability and maintain readability of proofs, we avoid using brute-force methods such as augmentation-substitution and Wu's method Wu [1978].