Many high-stakes AI applications target low-prevalence events, where apparent accuracy can conceal limited real-world value. Relevant AI models range from expert-defined rules and traditional machine learning to generative LLMs constrained for classification. We outline key considerations for critical appraisal of AI in rare-event recognition, including problem framing and test set design, prevalence-aware statistical evaluation, robustness assessment, and integration into human workflows. In addition, we propose an approach to structured case-level examination (SCLE), to complement statistical performance evaluation, and a comprehensive checklist to guide procurement or development of AI models for rare-event recognition. We instantiate the framework in pharmacovigilance, drawing on three studies: rule-based retrieval of pregnancy-related reports; duplicate detection combining machine learning with probabilistic record linkage; and automated redaction of person names using an LLM. We highlight pitfalls specific to the rare-event setting including optimism from unrealistic class balance and lack of difficult positive controls in test sets - and show how cost-sensitive targets align model performance with operational value. While grounded in pharmacovigilance practice, the principles generalize to domains where positives are scarce and error costs may be asymmetric.

Abstract--Explainability is increasingly seen as an essential feature of rule-based smart environments. While counterfactual explanations, which describe what could have been done differently to achieve a desired outcome, are a powerful tool in eXplainable AI (XAI), no established methods exist for generating them in these rule-based domains. In this paper, we present the first formalization and implementation of counterfactual explanations tailored to this domain. It is implemented as a plugin that extends an existing explanation engine for smart environments. We conducted a user study (N=17) to evaluate our generated counterfactuals against traditional causal explanations. The results show that user preference is highly contextual: causal explanations are favored for their linguistic simplicity and in time-pressured situations, while counterfactuals are preferred for their actionable content, particularly when a user wants to resolve a problem. Our work contributes a practical framework for a new type of explanation in smart environments and provides empirical evidence to guide the choice of when each explanation type is most effective. Smart environments, such as smart homes, offices, and buildings, integrate sensor-enabled devices to support users in decision-making, monitoring, and managing abnormal situations [1], [2]. The rapid adoption of these environments is fueled by advances in the Internet of Things (IoT) and Artificial Intelligence (AI), decreasing device costs, and improved system integration [3]-[5]. Rule-based systems are a prevalent approach for implementing automation in smart environments, by executing predefined rules when certain conditions are met [6], [7].

Purpose: This paper introduces a novel graph-based method, GARG-AML, for efficient and effective anti-money laundering (AML). It quantifies smurfing risk, a popular money laundering method, by providing each node in the network with a single interpretable score. The proposed method strikes a balance among computational efficiency, detection power and transparency. Different versions of GARG-AML are introduced for undirected and directed networks. Methodology: GARG-AML constructs the adjacency matrix of a node's second-order neighbourhood in a specific way. This allows us to use the density of different blocks in the adjacency matrix to express the neighbourhood's resemblance to a pure smurfing pattern. GARG-AML is extended using a decision tree and gradient-boosting classifier to increase its performance even more. The methods are tested on synthetic and on open-source data against the current state-of-the-art in AML. Findings: We find that GARG-AML obtains state-of-the-art performance on all datasets. We illustrate that GARG-AML scales well to massive transactions graphs encountered at financial institutions. By leveraging only the adjacency matrix of the second-order neighbourhood and basic network features, this work highlights the potential of fundamental network properties towards advancing fraud detection. Originality: This paper uses only basic network features and expert knowledge on smurfing to construct a performant AML system. The originality lies in the translation of smurfing detection to these features and network representation. Our proposed method is built around the real business needs of scalability and interpretability. It therefore provides a solution that can be easily implemented at financial institutions or incorporated in existing AML solutions.

However, the inference in MLNs is usually very difficult due to the complicated graph structures.

We propose DRUM, a scalable and differentiable approach for mining first-order logical rules from knowledge graphs which resolves these problems.

A data-driven approach, however, could overcome limitations in such rule-based approaches and improve precision mappings for individuals.

In the past decade, there has been a significant interest in the use of machine learning approaches in materials science research. Conventional deep learning approaches that rely on complex, nonlinear models have become increasingly important in computational materials science due to their high predictive accuracy. In contrast to these approaches, we have shown in a recent work that a remarkably simple learned heuristic rule -- based on the concept of topogivity -- can classify whether a material is topological using only its chemical composition. In this paper, we go beyond the topology classification scenario by also studying the use of machine learning to develop simple heuristic rules for classifying whether a material is a metal based on chemical composition. Moreover, we present a framework for incorporating chemistry-informed inductive bias based on the structure of the periodic table. For both the topology classification and the metallicity classification tasks, we empirically characterize the performance of simple heuristic rules fit with and without chemistry-informed inductive bias across a wide range of training set sizes. We find evidence that incorporating chemistry-informed inductive bias can reduce the amount of training data required to reach a given level of test accuracy.

The relationship between computing systems and the brain has served as motivation for pioneering theoreticians since John von Neumann and Alan Turing. Uniform, scale-free biological networks, such as the brain, have powerful properties, including generalizing over time, which is the main barrier for Machine Learning on the path to Universal Reasoning Models. We introduce `Dragon Hatchling' (BDH), a new Large Language Model architecture based on a scale-free biologically inspired network of \$n\$ locally-interacting neuron particles. BDH couples strong theoretical foundations and inherent interpretability without sacrificing Transformer-like performance. BDH is a practical, performant state-of-the-art attention-based state space sequence learning architecture. In addition to being a graph model, BDH admits a GPU-friendly formulation. It exhibits Transformer-like scaling laws: empirically BDH rivals GPT2 performance on language and translation tasks, at the same number of parameters (10M to 1B), for the same training data. BDH can be represented as a brain model. The working memory of BDH during inference entirely relies on synaptic plasticity with Hebbian learning using spiking neurons. We confirm empirically that specific, individual synapses strengthen connection whenever BDH hears or reasons about a specific concept while processing language inputs. The neuron interaction network of BDH is a graph of high modularity with heavy-tailed degree distribution. The BDH model is biologically plausible, explaining one possible mechanism which human neurons could use to achieve speech. BDH is designed for interpretability. Activation vectors of BDH are sparse and positive. We demonstrate monosemanticity in BDH on language tasks. Interpretability of state, which goes beyond interpretability of neurons and model parameters, is an inherent feature of the BDH architecture.