Early detection of cognitive disorders such as Alzheimer's disease is critical for enabling timely clinical intervention and improving patient outcomes. In this work, we introduce CogniAlign, a multimodal architecture for Alzheimer's detection that integrates audio and textual modalities, two non-intrusive sources of information that offer complementary insights into cognitive health. Unlike prior approaches that fuse modalities at a coarse level, CogniAlign leverages a word-level temporal alignment strategy that synchronizes audio embeddings with corresponding textual tokens based on transcription timestamps. This alignment supports the development of token-level fusion techniques, enabling more precise cross-modal interactions. To fully exploit this alignment, we propose a Gated Cross-Attention Fusion mechanism, where audio features attend over textual representations, guided by the superior unimodal performance of the text modality. In addition, we incorporate prosodic cues, specifically interword pauses, by inserting pause tokens into the text and generating audio embeddings for silent intervals, further enriching both streams. We evaluate CogniAlign on the ADReSSo dataset, where it achieves an accuracy of 87.35% over a Leave-One-Subject-Out setup and of 90.36% over a 5 fold Cross-Validation, outperforming existing state-of-the-art methods. A detailed ablation study confirms the advantages of our alignment strategy, attention-based fusion, and prosodic modeling. Finally, we perform a corpus analysis to assess the impact of the proposed prosodic features and apply Integrated Gradients to identify the most influential input segments used by the model in predicting cognitive health outcomes.

Medical image segmentation is a critical task in computer vision, with UNet serving as a milestone architecture. The typical component of UNet family is the skip connection, however, their skip connections face two significant limitations: (1) they lack effective interaction between features at different scales, and (2) they rely on simple concatenation or addition operations, which constrain efficient information integration. While recent improvements to UNet have focused on enhancing encoder and decoder capabilities, these limitations remain overlooked. To overcome these challenges, we propose a novel multi-scale feature fusion method that reimagines the UNet decoding process as solving an initial value problem (IVP), treating skip connections as discrete nodes. By leveraging principles from the linear multistep method, we propose an adaptive ordinary differential equation method to enable effective multi-scale feature fusion. Our approach is independent of the encoder and decoder architectures, making it adaptable to various U-Net-like networks. Experiments on ACDC, KiTS2023, MSD brain tumor, and ISIC2017/2018 skin lesion segmentation datasets demonstrate improved feature utilization, reduced network parameters, and maintained high performance. The code is available at https://github.com/nayutayuki/FuseUNet.

The advent of large-scale artificial intelligence (AI) models has a transformative effect on neuroscience research, which represents a paradigm shift from the traditional computational methods through the facilitation of end-to-end learning from raw brain signals and neural data. In this paper, we explore the transformative effects of large-scale AI models on five major neuroscience domains: neuroimaging and data processing, brain-computer interfaces and neural decoding, molecular neuroscience and genomic modeling, clinical assistance and translational frameworks, and disease-specific applications across neurological and psychiatric disorders. These models are demonstrated to address major computational neuroscience challenges, including multimodal neural data integration, spatiotemporal pattern interpretation, and the derivation of translational frameworks for clinical deployment. Moreover, the interaction between neuroscience and AI has become increasingly reciprocal, as biologically informed architectural constraints are now incorporated to develop more interpretable and computationally efficient models. This review highlights both the notable promise of such technologies and key implementation considerations, with particular emphasis on rigorous evaluation frameworks, effective domain knowledge integration, and comprehensive ethical guidelines for clinical use. Finally, a systematic listing of critical neuroscience datasets used to derive and validate large-scale AI models across diverse research applications is provided.

Memory systems are fundamental to AI agents, yet existing work often lacks adaptability to diverse tasks and overlooks the constructive and task-oriented role of AI agent memory. Drawing from Piaget's theory of cognitive development, we propose PISA, a pragmatic, psych-inspired unified memory system that addresses these limitations by treating memory as a constructive and adaptive process. To enable continuous learning and adaptability, PISA introduces a trimodal adaptation mechanism (i.e., schema updation, schema evolution, and schema creation) that preserves coherent organization while supporting flexible memory updates. Building on these schema-grounded structures, we further design a hybrid memory access architecture that seamlessly integrates symbolic reasoning with neural retrieval, significantly improving retrieval accuracy and efficiency. Our empirical evaluation, conducted on the existing LOCOMO benchmark and our newly proposed AggQA benchmark for data analysis tasks, confirms that PISA sets a new state-of-the-art by significantly enhancing adaptability and long-term knowledge retention.

The aim of multimodal neural networks is to combine diverse data sources, referred to as modalities, to achieve enhanced performance compared to relying on a single modality. However, training of multimodal networks is typically hindered by modality overfitting, where the network relies excessively on one of the available modalities. This often yields sub-optimal performance, hindering the potential of multimodal learning and resulting in marginal improvements relative to unimodal models. In this work, we present the Modality-Informed Learning ratE Scheduler (MILES) for training multimodal joint fusion models in a balanced manner. MILES leverages the differences in modality-wise conditional utilization rates during training to effectively balance multimodal learning. The learning rate is dynamically adjusted during training to balance the speed of learning from each modality by the multimodal model, aiming for enhanced performance in both multimodal and unimodal predictions. We extensively evaluate MILES on four multimodal joint fusion tasks and compare its performance to seven state-of-the-art baselines. Our results show that MILES outperforms all baselines across all tasks and fusion methods considered in our study, effectively balancing modality usage during training. This results in improved multimodal performance and stronger modality encoders, which can be leveraged when dealing with unimodal samples or absent modalities. Overall, our work highlights the impact of balancing multimodal learning on improving model performance.

Epilepsy is typically diagnosed through electroencephalography (EEG) and long-term video-EEG (vEEG) monitoring. The manual analysis of vEEG recordings is time-consuming, necessitating automated tools for seizure detection. Recent advancements in machine learning have shown promise in real-time seizure detection and prediction using EEG and video data. However, diversity of seizure symptoms, markup ambiguities, and limited availability of multimodal datasets hinder progress. This paper reviews the latest developments in automated video-EEG analysis and discusses the integration of multimodal data. We also propose a novel pipeline for treatment effect estimation from vEEG data using concept-based learning, offering a pathway for future research in this domain.

This paper presents a novel fusion technique for LiDAR Simultaneous Localization and Mapping (SLAM), aimed at improving localization and 3D mapping using LiDAR sensor. Our approach centers on the Inferred Attention Fusion (INAF) module, which integrates AI with geometric odometry. Utilizing the KITTI dataset's LiDAR data, INAF dynamically adjusts attention weights based on environmental feedback, enhancing the system's adaptability and measurement accuracy. This method advances the precision of both localization and 3D mapping, demonstrating the potential of our fusion technique to enhance autonomous navigation systems in complex scenarios.

Autonomous navigation for legged robots in complex and dynamic environments relies on robust simultaneous localization and mapping (SLAM) systems to accurately map surroundings and localize the robot, ensuring safe and efficient operation. While prior sensor fusion-based SLAM approaches have integrated various sensor modalities to improve their robustness, these algorithms are still susceptible to estimation drift in challenging environments due to their reliance on unsuitable fusion strategies. Therefore, we propose a robust LiDAR-visual-inertial-kinematic odometry system that integrates information from multiple sensors, such as a camera, LiDAR, inertial measurement unit (IMU), and joint encoders, for visual and LiDAR-based odometry estimation. Our system employs a fusion-based pose estimation approach that runs optimization-based visual-inertial-kinematic odometry (VIKO) and filter-based LiDAR-inertial-kinematic odometry (LIKO) based on measurement availability. In VIKO, we utilize the footpreintegration technique and robust LiDAR-visual depth consistency using superpixel clusters in a sliding window optimization. In LIKO, we incorporate foot kinematics and employ a point-toplane residual in an error-state iterative Kalman filter (ESIKF). Compared with other sensor fusion-based SLAM algorithms, our approach shows robust performance across public and longterm datasets.

In this paper we develop a deforestation detection pipeline that incorporates optical and Synthetic Aperture Radar (SAR) data. A crucial component of the pipeline is the construction of anomaly maps of the optical data, which is done using the residual space of a discrete Karhunen-Loève (KL) expansion. Anomalies are quantified using a concentration bound on the distribution of the residual components for the nominal state of the forest. This bound does not require prior knowledge on the distribution of the data. This is in contrast to statistical parametric methods that assume knowledge of the data distribution, an impractical assumption that is especially infeasible for high dimensional data such as ours. Once the optical anomaly maps are computed they are combined with SAR data, and the state of the forest is classified by using a Hidden Markov Model (HMM). We test our approach with Sentinel-1 (SAR) and Sentinel-2 (Optical) data on a $92.19\,km \times 91.80\,km$ region in the Amazon forest. The results show that both the hybrid optical-radar and optical only methods achieve high accuracy that is superior to the recent state-of-the-art hybrid method. Moreover, the hybrid method is significantly more robust in the case of sparse optical data that are common in highly cloudy regions.

Robot vision has greatly benefited from advancements in multimodal fusion techniques and vision-language models (VLMs). We adopt a task-oriented perspective to systematically review the applications and advancements of multimodal fusion methods and VLMs in the field of robot vision. For semantic scene understanding tasks, we categorize fusion approaches into encoder-decoder frameworks, attention-based architectures, and graph neural networks. Meanwhile, we also analyze the architectural characteristics and practical implementations of these fusion strategies in key tasks such as simultaneous localization and mapping (SLAM), 3D object detection, navigation, and manipulation. We compare the evolutionary paths and applicability of VLMs based on large language models (LLMs) with traditional multimodal fusion methods.Additionally, we conduct an in-depth analysis of commonly used datasets, evaluating their applicability and challenges in real-world robotic scenarios. Building on this analysis, we identify key challenges in current research, including cross-modal alignment, efficient fusion, real-time deployment, and domain adaptation. We propose future directions such as self-supervised learning for robust multimodal representations, structured spatial memory and environment modeling to enhance spatial intelligence, and the integration of adversarial robustness and human feedback mechanisms to enable ethically aligned system deployment. Through a comprehensive review, comparative analysis, and forward-looking discussion, we provide a valuable reference for advancing multimodal perception and interaction in robotic vision. A comprehensive list of studies in this survey is available at https://github.com/Xiaofeng-Han-Res/MF-RV.