Turing machine and decision tree have developed independently for a long time. With the recent development of differentiable models, there is an intersection between them. Neural turing machine(NTM) opens door for the memory network. It use differentiable attention mechanism to read/write external memory bank. Differentiable forest brings differentiable properties to classical decision tree. In this short note, we show the deep connection between these two models. That is: differentiable forest is a special case of NTM. Differentiable forest is actually decision tree based neural turing machine. Based on this deep connection, we propose a response augmented differential forest (RaDF). The controller of RaDF is differentiable forest, the external memory of RaDF are response vectors which would be read/write by leaf nodes.

Individual Treatment Effect (ITE) estimation is an extensively researched problem, with applications in various domains. We model the case where there exists heterogeneous non-compliance to a randomly assigned treatment, a typical situation in health (because of non-compliance to prescription) or digital advertising (because of competition and ad blockers for instance). The lower the compliance, the more the effect of treatment prescription, or individual prescription effect (IPE), signal fades away and becomes hard to estimate. We propose a new approach for the estimation of the IPE that takes advantage of observed compliance information to prevent signal fading. Using the Structural Causal Model framework and do-calculus, we define a general mediated causal effect setting and propose a corresponding estimator which consistently recovers the IPE with asymptotic variance guarantees. Finally, we conduct experiments on both synthetic and real-world datasets that highlight the benefit of the approach, which consistently improves state-of-the-art in low compliance settings

Inferring the causal direction and causal effect between two discrete random variables X and Y from a finite sample is often a crucial problem and a challenging task. However, if we have access to observational and interventional data, it is possible to solve that task. If X is causing Y, then it does not matter if we observe an effect in Y by observing changes in X or by intervening actively on X. This invariance principle creates a link between observational and interventional distributions in a higher dimensional probability space. We embed distributions that originate from samples of X and Y into that higher dimensional space such that the embedded distribution is closest to the distributions that follow the invariance principle, with respect to the relative entropy. This allows us to calculate the best information-theoretic approximation for a given empirical distribution, that follows an assumed underlying causal model. We show that this information-theoretic approximation to causal models (IACM) can be done by solving a linear optimization problem. In particular, by approximating the empirical distribution to a monotonic causal model, we can calculate probabilities of causation. We can also use IACM for causal discovery problems in the bivariate, discrete case. However, experimental results on labeled synthetic data from additive noise models show that our causal discovery approach is lagging behind state-of-the-art approaches because the invariance principle encodes only a necessary condition for causal relations. Nevertheless, for synthetic multiplicative noise data and real-world data, our approach can compete in some cases with alternative methods.

Diagnosis of Parkinson's disease (PD) is commonly based on medical observations and assessment of clinical signs, including the characterization of a variety of motor symptoms. However, traditional diagnostic approaches may suffer from subjectivity as they rely on the evaluation of movements that are sometimes subtle to human eyes and therefore difficult to classify, leading to possible misclassification. In the meantime, early non-motor symptoms of PD may be mild and can be caused by many other conditions. Therefore, these symptoms are often overlooked, making diagnosis of PD at an early stage challenging. To address these difficulties and to refine the diagnosis and assessment procedures of PD, machine learning methods have been implemented for the classification of PD and healthy controls or patients with similar clinical presentations (e.g., movement disorders or other Parkinsonian syndromes). To provide a comprehensive overview of data modalities and machine learning methods that have been used in the diagnosis and differential diagnosis of PD, in this study, we conducted a systematic literature review of studies published until February 14, 2020, using the PubMed and IEEE Xplore databases. A total of 209 studies were included, extracted for relevant information and presented in this systematic review, with an investigation of their aims, sources of data, types of data, machine learning methods and associated outcomes. These studies demonstrate a high potential for adaptation of machine learning methods and novel biomarkers in clinical decision making, leading to increasingly systematic, informed diagnosis of PD.

Language is a valuable source of clinical information in Alzheimer's Disease, as it declines concurrently with neurodegeneration. Consequently, speech and language data have been extensively studied in connection with its diagnosis. This paper summarises current findings on the use of artificial intelligence, speech and language processing to predict cognitive decline in the context of Alzheimer's Disease, detailing current research procedures, highlighting their limitations and suggesting strategies to address them. We conducted a systematic review of original research between 2000 and 2019, registered in PROSPERO (reference CRD42018116606). An interdisciplinary search covered six databases on engineering (ACM and IEEE), psychology (PsycINFO), medicine (PubMed and Embase) and Web of Science. Bibliographies of relevant papers were screened until December 2019. From 3,654 search results 51 articles were selected against the eligibility criteria. Four tables summarise their findings: study details (aim, population, interventions, comparisons, methods and outcomes), data details (size, type, modalities, annotation, balance, availability and language of study), methodology (pre-processing, feature generation, machine learning, evaluation and results) and clinical applicability (research implications, clinical potential, risk of bias and strengths/limitations). While promising results are reported across nearly all 51 studies, very few have been implemented in clinical research or practice. We concluded that the main limitations of the field are poor standardisation, limited comparability of results, and a degree of disconnect between study aims and clinical applications. Attempts to close these gaps should support translation of future research into clinical practice.

Parent and Child Node - The node which get divided into several sub-node is parent node and the sub-node formed is called child node. Parent and Child Node - The node which get divided into several sub-node is parent node and the sub-node formed is called child node. Subtree /Branch - If a subnode again split into further subnodes that entire part is called subtree (one Parent - Child part).It is a part of entire tree. Subtree /Branch - If a subnode again split into further subnodes that entire part is called subtree (one Parent - Child part).It is a part of entire tree. Decision Node - If a subnode split into further subnodes Then that splitted subnode is called decision node.

Various model-based diagnosis scenarios require the computation of most preferred fault explanations. Existing algorithms that are sound (i.e., output only actual fault explanations) and complete (i.e., can return all explanations), however, require exponential space to achieve this task. As a remedy, we propose two novel diagnostic search algorithms, called RBF-HS (Recursive Best-First Hitting Set Search) and HBF-HS (Hybrid Best-First Hitting Set Search), which build upon tried and tested techniques from the heuristic search domain. RBF-HS can enumerate an arbitrary predefined finite number of fault explanations in best-first order within linear space bounds, without sacrificing the desirable soundness or completeness properties. The idea of HBF-HS is to find a trade-off between runtime optimization and a restricted space consumption that does not exceed the available memory. In extensive experiments on real-world diagnosis cases we compared our approaches to Reiter's HS-Tree, a state-of-the-art method that gives the same theoretical guarantees and is as general(ly applicable) as the suggested algorithms. For the computation of minimum-cardinality fault explanations, we find that (1) RBF-HS reduces memory requirements substantially in most cases by up to several orders of magnitude, (2) in more than a third of the cases, both memory savings and runtime savings are achieved, and (3) given the runtime overhead is significant, using HBF-HS instead of RBF-HS reduces the runtime to values comparable with HS-Tree while keeping the used memory reasonably bounded. When computing most probable fault explanations, we observe that RBF-HS tends to trade memory savings more or less one-to-one for runtime overheads. Again, HBF-HS proves to be a reasonable remedy to cut down the runtime while complying with practicable memory bounds.

Experts fear the U.S. will see thousands more cancer deaths in the coming years due to delayed screenings, treatments and trials; Dr. Marc Siegel reacts. Throat cancer is a term that can apply to several different types of cancers that occur in different locations in the head and neck. In 2018, more than 30,000 people in the U.S. received a throat cancer diagnosis of some kind, according to MD Anderson Cancer Center. Both laryngeal and hypopharyngeal cancers start in the lower part of the throat. Patients diagnosed with laryngeal cancer mean that the disease was detected in an area affecting the voice box, including the supraglottis, which is located above the vocal cords, the glottis, which contains the vocal cords or the subglottis, which is below the vocal cords, according to the American Cancer Society.

Software often produces biased outputs. In particular, machine learning (ML) based software are known to produce erroneous predictions when processing discriminatory inputs. Such unfair program behavior can be caused by societal bias. In the last few years, Amazon, Microsoft and Google have provided software services that produce unfair outputs, mostly due to societal bias (e.g. gender or race). In such events, developers are saddled with the task of conducting fairness testing. Fairness testing is challenging; developers are tasked with generating discriminatory inputs that reveal and explain biases. We propose a grammar-based fairness testing approach (called ASTRAEA) which leverages context-free grammars to generate discriminatory inputs that reveal fairness violations in software systems. Using probabilistic grammars, ASTRAEA also provides fault diagnosis by isolating the cause of observed software bias. ASTRAEA's diagnoses facilitate the improvement of ML fairness. ASTRAEA was evaluated on 18 software systems that provide three major natural language processing (NLP) services. In our evaluation, ASTRAEA generated fairness violations with a rate of ~18%. ASTRAEA generated over 573K discriminatory test cases and found over 102K fairness violations. Furthermore, ASTRAEA improves software fairness by ~76%, via model-retraining.

This article was published as a part of the Data Science Blogathon. Decision Tree is one of the most intuitive and effective tools present in a Data Scientist's toolkit. It has an inverted tree-like structure that was once used only in Decision Analysis but is now a brilliant Machine Learning Algorithm as well, especially when we have a Classification problem on our hands. These decision trees are well-known for their capability to capture the patterns in the data. But, excess of anything is harmful, right?