Current progress in the artificial intelligence domain has led to the development of various types of AI-powered dementia assessments, which can be employed to identify patients at the early stage of dementia. It can revolutionize the dementia care settings. It is essential that the medical community be aware of various AI assessments and choose them considering their degrees of validity, efficiency, practicality, reliability, and accuracy concerning the early identification of patients with dementia (PwD). On the other hand, AI developers should be informed about various non-AI assessments as well as recently developed AI assessments. Thus, this paper, which can be readable by both clinicians and AI engineers, fills the gap in the literature in explaining the existing solutions for the recognition of dementia to clinicians, as well as the techniques used and the most widespread dementia datasets to AI engineers. It follows a review of papers on AI and non-AI assessments for dementia to provide valuable information about various dementia assessments for both the AI and medical communities.

Fault diagnosis is essential in industrial processes for monitoring the conditions of important machines. With the ever-increasing complexity of working conditions and demand for safety during production and operation, different diagnosis methods are required, and more importantly, an integrated fault diagnosis system that can cope with multiple tasks is highly desired. However, the diagnosis subtasks are often studied separately, and the currently available methods still need improvement for such a generalized system. To address this issue, we propose the Generalized Out-of-distribution Fault Diagnosis (GOOFD) framework to integrate diagnosis subtasks, such as fault detection, fault classification, and novel fault diagnosis. Additionally, a unified fault diagnosis method based on internal contrastive learning is put forward to underpin the proposed generalized framework. The method extracts features utilizing the internal contrastive learning technique and then recognizes the outliers based on the Mahalanobis distance. Experiments are conducted on a simulated benchmark dataset as well as two practical process datasets to evaluate the proposed framework. As demonstrated in the experiments, the proposed method achieves better performance compared with several existing techniques and thus verifies the effectiveness of the proposed framework.

The reliable operation of automatic systems is heavily dependent on the ability to detect faults in the underlying dynamical system. While traditional model-based methods have been widely used for fault detection, data-driven approaches have garnered increasing attention due to their ease of deployment and minimal need for expert knowledge. In this paper, we present a novel principal component analysis (PCA) method that uses occupation kernels. Occupation kernels result in feature maps that are tailored to the measured data, have inherent noise-robustness due to the use of integration, and can utilize irregularly sampled system trajectories of variable lengths for PCA. The occupation kernel PCA method is used to develop a reconstruction error approach to fault detection and its efficacy is validated using numerical simulations.

In the modern world, we are permanently using, leveraging, interacting with, and relying upon systems of ever higher sophistication, ranging from our cars, recommender systems in e-commerce, and networks when we go online, to integrated circuits when using our PCs and smartphones, the power grid to ensure our energy supply, security-critical software when accessing our bank accounts, and spreadsheets for financial planning and decision making. The complexity of these systems coupled with our high dependency on them implies both a non-negligible likelihood of system failures, and a high potential that such failures have significant negative effects on our everyday life. For that reason, it is a vital requirement to keep the harm of emerging failures to a minimum, which means minimizing the system downtime as well as the cost of system repair. This is where model-based diagnosis comes into play. Model-based diagnosis is a principled, domain-independent approach that can be generally applied to troubleshoot systems of a wide variety of types, including all the ones mentioned above, and many more. It exploits and orchestrates i.a. techniques for knowledge representation, automated reasoning, heuristic problem solving, intelligent search, optimization, stochastics, statistics, decision making under uncertainty, machine learning, as well as calculus, combinatorics and set theory to detect, localize, and fix faults in abnormally behaving systems. In this thesis, we will give an introduction to the topic of model-based diagnosis, point out the major challenges in the field, and discuss a selection of approaches from our research addressing these issues.

Fox News medical contributor Dr. Janette Nesheiwat joins'Fox News Live' to discuss the results of an Alzheimer's drug trial by Eli Lilly. Alzheimer's is a disease that heavily impacts memory function, typically in older people. Since memory loss commonly comes with aging, it can be hard to detect if a symptom is just one that comes with old age, or a sign of Alzheimer's disease. The main symptom of Alzheimer's disease is memory loss. More than that, it's memory loss that happens frequently and gets worse over time.

Convolutional Neural Networks (CNNs) are widely used in fault diagnosis of mechanical systems due to their powerful feature extraction and classification capabilities. However, the CNN is a typical black-box model, and the mechanism of CNN's decision-making are not clear, which limits its application in high-reliability-required fault diagnosis scenarios. To tackle this issue, we propose a novel interpretable neural network termed as Time-Frequency Network (TFN), where the physically meaningful time-frequency transform (TFT) method is embedded into the traditional convolutional layer as an adaptive preprocessing layer. This preprocessing layer named as time-frequency convolutional (TFconv) layer, is constrained by a well-designed kernel function to extract fault-related time-frequency information. It not only improves the diagnostic performance but also reveals the logical foundation of the CNN prediction in the frequency domain. Different TFT methods correspond to different kernel functions of the TFconv layer. In this study, four typical TFT methods are considered to formulate the TFNs and their effectiveness and interpretability are proved through three mechanical fault diagnosis experiments. Experimental results also show that the proposed TFconv layer can be easily generalized to other CNNs with different depths. The code of TFN is available on https://github.com/ChenQian0618/TFN.

Ensuring diagnostic performance of AI models before clinical use is key to the safe and successful adoption of these technologies. Studies reporting AI applied to digital pathology images for diagnostic purposes have rapidly increased in number in recent years. The aim of this work is to provide an overview of the diagnostic accuracy of AI in digital pathology images from all areas of pathology. This systematic review and meta-analysis included diagnostic accuracy studies using any type of artificial intelligence applied to whole slide images (WSIs) in any disease type. The reference standard was diagnosis through histopathological assessment and / or immunohistochemistry. Searches were conducted in PubMed, EMBASE and CENTRAL in June 2022. We identified 2976 studies, of which 100 were included in the review and 48 in the full meta-analysis. Risk of bias and concerns of applicability were assessed using the QUADAS-2 tool. Data extraction was conducted by two investigators and meta-analysis was performed using a bivariate random effects model. 100 studies were identified for inclusion, equating to over 152,000 whole slide images (WSIs) and representing many disease types. Of these, 48 studies were included in the meta-analysis. These studies reported a mean sensitivity of 96.3% (CI 94.1-97.7) and mean specificity of 93.3% (CI 90.5-95.4) for AI. There was substantial heterogeneity in study design and all 100 studies identified for inclusion had at least one area at high or unclear risk of bias. This review provides a broad overview of AI performance across applications in whole slide imaging. However, there is huge variability in study design and available performance data, with details around the conduct of the study and make up of the datasets frequently missing. Overall, AI offers good accuracy when applied to WSIs but requires more rigorous evaluation of its performance.

The diagnosis of faults present in a REM is integrated by the detection, identification and isolation of an anomaly, which can be achieved by using the information obtained on the state of operation of the equipment or drive [3]. As a result, it is possible to consider fault diagnosis as a pattern recognition problem with respect to the condition of a REM [4]. To effectively diagnose faults in a REM, it is essential to distinguish between failures originating from the machine itself, whether electrical or mechanical, and those corresponding to the associated load [5]. In recent decades, with the advancement of communication technologies and the inclusion of control devices in REM, non-invasive faults detection and diagnosis techniques based on the use of electrical variables have been studied more than those that use acoustic emissions, analysis lubrication, thermography and vibrations. The latter have been the techniques most widely used for some time, in which different methods are used for analysis, among the most common, Fast Fourier Transform (FFT) in the frequency domain, and wavelet analysis and empirical model decomposition in the domain time-frequency [6].

Diagnosis in PV systems aims to detect, locate and identify faults. Diagnosing these faults is vital to guarantee energy production and extend the useful life of PV power plants. In the literature, multiple machine learning approaches have been proposed for this purpose. However, few of these works have paid special attention to the detection of fine faults and the specialized process of extraction and selection of features for their classification. A fine fault is one whose characteristic signature is difficult to distinguish to that of a healthy panel. As a contribution to the detection of fine faults (especially of the snail trail type), this article proposes an innovative approach based on the Random Forest (RF) algorithm. This approach uses a complex feature extraction and selection method that improves the computational time of fault classification while maintaining high accuracy.

Generative artificial intelligence (AI) is a promising direction for augmenting clinical diagnostic decision support and reducing diagnostic errors, a leading contributor to medical errors. To further the development of clinical AI systems, the Diagnostic Reasoning Benchmark (DR.BENCH) was introduced as a comprehensive generative AI framework, comprised of six tasks representing key components in clinical reasoning. We present a comparative analysis of in-domain versus out-of-domain language models as well as multi-task versus single task training with a focus on the problem summarization task in DR.BENCH (Gao et al., 2023). We demonstrate that a multi-task, clinically trained language model outperforms its general domain counterpart by a large margin, establishing a new state-of-the-art performance, with a ROUGE-L score of 28.55. This research underscores the value of domain-specific training for optimizing clinical diagnostic reasoning tasks.