Despite the remarkable results that can be achieved by data-driven intelligent fault diagnosis techniques, they presuppose the same distribution of training and test data as well as sufficient labeled data. Various operating states often exist in practical scenarios, leading to the problem of domain shift that hinders the effectiveness of fault diagnosis. While recent unsupervised domain adaptation methods enable cross-domain fault diagnosis, they struggle to effectively utilize information from multiple source domains and achieve effective diagnosis faults in multiple target domains simultaneously. In this paper, we innovatively proposed a weighted joint maximum mean discrepancy enabled multi-source-multi-target unsupervised domain adaptation (WJMMD-MDA), which realizes domain adaptation under multi-source-multi-target scenarios in the field of fault diagnosis for the first time. The proposed method extracts sufficient information from multiple labeled source domains and achieves domain alignment between source and target domains through an improved weighted distance loss. As a result, domain-invariant and discriminative features between multiple source and target domains are learned with cross-domain fault diagnosis realized. The performance of the proposed method is evaluated in comprehensive comparative experiments on three datasets, and the experimental results demonstrate the superiority of this method.

The accurate classification of lymphoma subtypes using hematoxylin and eosin (H&E)-stained tissue is complicated by the wide range of morphological features these cancers can exhibit. We present LymphoML - an interpretable machine learning method that identifies morphologic features that correlate with lymphoma subtypes. Our method applies steps to process H&E-stained tissue microarray cores, segment nuclei and cells, compute features encompassing morphology, texture, and architecture, and train gradient-boosted models to make diagnostic predictions. LymphoML's interpretable models, developed on a limited volume of H&E-stained tissue, achieve non-inferior diagnostic accuracy to pathologists using whole-slide images and outperform black box deep-learning on a dataset of 670 cases from Guatemala spanning 8 lymphoma subtypes. Using SHapley Additive exPlanation (SHAP) analysis, we assess the impact of each feature on model prediction and find that nuclear shape features are most discriminative for DLBCL (F1-score: 78.7%) and classical Hodgkin lymphoma (F1-score: 74.5%). Finally, we provide the first demonstration that a model combining features from H&E-stained tissue with features from a standardized panel of 6 immunostains results in a similar diagnostic accuracy (85.3%) to a 46-stain panel (86.1%).

A significant challenge for predictive maintenance in the pulp-and-paper industry is the infrequency of paper breaks during the production process. In this article, operational data is analyzed from a paper manufacturing machine in which paper breaks are relatively rare but have a high economic impact. Utilizing a dataset comprising 18,398 instances derived from a quality assurance protocol, we address the scarcity of break events (124 cases) that pose a challenge for machine learning predictive models. With the help of Conditional Generative Adversarial Networks (CTGAN) and Synthetic Minority Oversampling Technique (SMOTE), we implement a novel data augmentation framework. This method ensures that the synthetic data mirrors the distribution of the real operational data but also seeks to enhance the performance metrics of predictive modeling. Before and after the data augmentation, we evaluate three different machine learning algorithms-Decision Trees (DT), Random Forest (RF), and Logistic Regression (LR). Utilizing the CTGAN-enhanced dataset, our study achieved significant improvements in predictive maintenance performance metrics. The efficacy of CTGAN in addressing data scarcity was evident, with the models' detection of machine breaks (Class 1) improving by over 30% for Decision Trees, 20% for Random Forest, and nearly 90% for Logistic Regression. With this methodological advancement, this study contributes to industrial quality control and maintenance scheduling by addressing rare event prediction in manufacturing processes.

Answering counterfactual queries has many important applications such as knowledge discovery and explainability, but is challenging when causal variables are unobserved and we only see a projection onto an observation space, for instance, image pixels. One approach is to recover the latent Structural Causal Model (SCM), but this typically needs unrealistic assumptions, such as linearity of the causal mechanisms. Another approach is to use na\"ive ML approximations, such as generative models, to generate counterfactual samples; however, these lack guarantees of accuracy. In this work, we strive to strike a balance between practicality and theoretical guarantees by focusing on a specific type of causal query called domain counterfactuals, which hypothesizes what a sample would have looked like if it had been generated in a different domain (or environment). Concretely, by only assuming invertibility, sparse domain interventions and access to observational data from different domains, we aim to improve domain counterfactual estimation both theoretically and practically with less restrictive assumptions. We define domain counterfactually equivalent models and prove necessary and sufficient properties for equivalent models that provide a tight characterization of the domain counterfactual equivalence classes. Building upon this result, we prove that every equivalence class contains a model where all intervened variables are at the end when topologically sorted by the causal DAG. This surprising result suggests that a model design that only allows intervention in the last $k$ latent variables may improve model estimation for counterfactuals. We then test this model design on extensive simulated and image-based experiments which show the sparse canonical model indeed improves counterfactual estimation over baseline non-sparse models.

In recent decades, Industrial Fault Diagnosis (IFD) has emerged as a crucial discipline concerned with detecting and gathering vital information about industrial equipment's health condition, thereby facilitating the identification of failure types and severities. The pursuit of precise and effective fault recognition has garnered substantial attention, culminating in a focus on automating equipment monitoring to preclude safety accidents and reduce reliance on human labor. The advent of artificial neural networks (ANNs) has been instrumental in augmenting intelligent IFD algorithms, particularly in the context of big data. Despite these advancements, ANNs, being a simplified biomimetic neural network model, exhibit inherent limitations such as resource and data dependencies and restricted cognitive capabilities. To address these limitations, the third-generation Spiking Neural Network (SNN), founded on principles of Brain-inspired computing, has surfaced as a promising alternative. The SNN, characterized by its biological neuron dynamics and spiking information encoding, demonstrates exceptional potential in representing spatiotemporal features. Consequently, developing SNN-based IFD models has gained momentum, displaying encouraging performance. Nevertheless, this field lacks systematic surveys to illustrate the current situation, challenges, and future directions. Therefore, this paper systematically reviews the theoretical progress of SNN-based models to answer the question of what SNN is. Subsequently, it reviews and analyzes existing SNN-based IFD models to explain why SNN needs to be used and how to use it. More importantly, this paper systematically answers the challenges, solutions, and opportunities of SNN in IFD.

Recent digital advances have popularized predictive maintenance (PMx), offering enhanced efficiency, automation, accuracy, cost savings, and independence in maintenance. Yet, it continues to face numerous limitations such as poor explainability, sample inefficiency of data-driven methods, complexity of physics-based methods, and limited generalizability and scalability of knowledge-based methods. This paper proposes leveraging Digital Twins (DTs) to address these challenges and enable automated PMx adoption at larger scales. While we argue that DTs have this transformative potential, they have not yet reached the level of maturity needed to bridge these gaps in a standardized way. Without a standard definition for such evolution, this transformation lacks a solid foundation upon which to base its development. This paper provides a requirement-based roadmap supporting standardized PMx automation using DT technologies. A systematic approach comprising two primary stages is presented. First, we methodically identify the Informational Requirements (IRs) and Functional Requirements (FRs) for PMx, which serve as a foundation from which any unified framework must emerge. Our approach to defining and using IRs and FRs to form the backbone of any PMx DT is supported by the track record of IRs and FRs being successfully used as blueprints in other areas, such as for product development within the software industry. Second, we conduct a thorough literature review spanning fields to determine the ways in which these IRs and FRs are currently being used within DTs, enabling us to point to the specific areas where further research is warranted to support the progress and maturation of requirement-based PMx DTs.

ODTLearn is an open-source Python package that provides methods for learning optimal decision trees for high-stakes predictive and prescriptive tasks based on the mixed-integer optimization (MIO) framework proposed in (Aghaei et al., 2019) and several of its extensions. The current version of the package provides implementations for learning optimal classification trees, optimal fair classification trees, optimal classification trees robust to distribution shifts, and optimal prescriptive trees from observational data. We have designed the package to be easy to maintain and extend as new optimal decision tree problem classes, reformulation strategies, and solution algorithms are introduced. To this end, the package follows object-oriented design principles and supports both commercial (Gurobi) and open source (COIN-OR branch and cut) solvers.

Ball mills play a critical role in modern mining operations, making their bearing failures a significant concern due to the potential loss of production efficiency and economic consequences. This paper presents an anomaly detection method based on Deep Convolutional Auto-encoding Neural Networks (DCAN) for addressing the issue of ball mill bearing fault detection. The proposed approach leverages vibration data collected during normal operation for training, overcoming challenges such as labeling issues and data imbalance often encountered in supervised learning methods. DCAN includes the modules of convolutional feature extraction and transposed convolutional feature reconstruction, demonstrating exceptional capabilities in signal processing and feature extraction. Additionally, the paper describes the practical deployment of the DCAN-based anomaly detection model for bearing fault detection, utilizing data from the ball mill bearings of Wuhan Iron & Steel Resources Group and fault data from NASA's bearing vibration dataset. Experimental results validate the DCAN model's reliability in recognizing fault vibration patterns. This method holds promise for enhancing bearing fault detection efficiency, reducing production interruptions, and lowering maintenance costs.

For explainable fault detection and classification (FDC), this paper proposes a unified framework, ABIGX (Adversarial fault reconstruction-Based Integrated Gradient eXplanation). ABIGX is derived from the essentials of previous successful fault diagnosis methods, contribution plots (CP) and reconstruction-based contribution (RBC). It is the first explanation framework that provides variable contributions for the general FDC models. The core part of ABIGX is the adversarial fault reconstruction (AFR) method, which rethinks the FR from the perspective of adversarial attack and generalizes to fault classification models with a new fault index. For fault classification, we put forward a new problem of fault class smearing, which intrinsically hinders the correct explanation. We prove that ABIGX effectively mitigates this problem and outperforms the existing gradient-based explanation methods. For fault detection, we theoretically bridge ABIGX with conventional fault diagnosis methods by proving that CP and RBC are the linear specifications of ABIGX. The experiments evaluate the explanations of FDC by quantitative metrics and intuitive illustrations, the results of which show the general superiority of ABIGX to other advanced explanation methods.

The advances in Artificial Intelligence (AI) and Machine Learning (ML) have opened up many avenues for scientific research, and are adding new dimensions to the process of knowledge creation. However, even the most powerful and versatile of ML applications till date are primarily in the domain of analysis of associations and boil down to complex data fitting. Judea Pearl has pointed out that Artificial General Intelligence must involve interventions involving the acts of doing and imagining. Any machine assisted scientific discovery thus must include casual analysis and interventions. In this context, we propose a causal learning model of physical principles, which not only recognizes correlations but also brings out casual relationships. We use the principles of causal inference and interventions to study the cause-and-effect relationships in the context of some well-known physical phenomena. We show that this technique can not only figure out associations among data, but is also able to correctly ascertain the cause-and-effect relations amongst the variables, thereby strengthening (or weakening) our confidence in the proposed model of the underlying physical process.