Deriving health indicators of rotating machines is crucial for their maintenance. However, this process is challenging for the prevalent adopted intelligent methods since they may take the whole data distributions, not only introducing noise interference but also lacking the explainability. To address these issues, we propose a diffusion-based weakly-supervised approach for deriving health indicators of rotating machines, enabling early fault detection and continuous monitoring of condition evolution. This approach relies on a classifier-free diffusion model trained using healthy samples and a few anomalies. This model generates healthy samples. and by comparing the differences between the original samples and the generated ones in the envelope spectrum, we construct an anomaly map that clearly identifies faults. Health indicators are then derived, which can explain the fault types and mitigate noise interference. Comparative studies on two cases demonstrate that the proposed method offers superior health monitoring effectiveness and robustness compared to baseline models.

The escalating global mortality and morbidity rates associated with gastrointestinal (GI) bleeding, compounded by the complexities and limitations of traditional endoscopic methods, underscore the urgent need for a critical review of current methodologies used for addressing this condition. With an estimated 300,000 annual deaths worldwide, the demand for innovative diagnostic and therapeutic strategies is paramount. The introduction of Video Capsule Endoscopy (VCE) has marked a significant advancement, offering a comprehensive, non-invasive visualization of the digestive tract that is pivotal for detecting bleeding sources unattainable by traditional methods. Despite its benefits, the efficacy of VCE is hindered by diagnostic challenges, including time-consuming analysis and susceptibility to human error. This backdrop sets the stage for exploring Machine Learning (ML) applications in automating GI bleeding detection within capsule endoscopy, aiming to enhance diagnostic accuracy, reduce manual labor, and improve patient outcomes. Through an exhaustive analysis of 113 papers published between 2008 and 2023, this review assesses the current state of ML methodologies in bleeding detection, highlighting their effectiveness, challenges, and prospective directions. It contributes an in-depth examination of AI techniques in VCE frame analysis, offering insights into open-source datasets, mathematical performance metrics, and technique categorization. The paper sets a foundation for future research to overcome existing challenges, advancing gastrointestinal diagnostics through interdisciplinary collaboration and innovation in ML applications.

In the realm of dermatology, the complexity of diagnosing skin conditions manually necessitates the expertise of dermatologists. Accurate identification of various skin ailments, ranging from cancer to inflammatory diseases, is paramount. However, existing artificial intelligence (AI) models in dermatology face challenges, particularly in accurately diagnosing diseases across diverse skin tones, with a notable performance gap in darker skin. Additionally, the scarcity of publicly available, unbiased datasets hampers the development of inclusive AI diagnostic tools. To tackle the challenges in accurately predicting skin conditions across diverse skin tones, we employ a transfer-learning approach that capitalizes on the rich, transferable knowledge from various image domains. Our method integrates multiple pre-trained models from a wide range of sources, including general and specific medical images, to improve the robustness and inclusiveness of the skin condition predictions. We rigorously evaluated the effectiveness of these models using the Diverse Dermatology Images (DDI) dataset, which uniquely encompasses both underrepresented and common skin tones, making it an ideal benchmark for assessing our approach. Among all methods, Med-ViT emerged as the top performer due to its comprehensive feature representation learned from diverse image sources. To further enhance performance, we conducted domain adaptation using additional skin image datasets such as HAM10000. This adaptation significantly improved model performance across all models.

This paper discusses algorithms for learning causal DAGs. The PC algorithm makes no assumptions other than the faithfulness to the causal model and can identify only up to the Markov equivalence class. LiNGAM assumes linearity and continuous non-Gaussian disturbances for the causal model, and the causal DAG defining LiNGAM is shown to be fully identifiable. The PC-LiNGAM, a hybrid of the PC algorithm and LiNGAM, can identify up to the distribution-equivalence pattern of a linear causal model, even in the presence of Gaussian disturbances. However, in the worst case, the PC-LiNGAM has factorial time complexity for the number of variables. In this paper, we propose an algorithm for learning the distribution-equivalence patterns of a linear causal model with a lower time complexity than PC-LiNGAM, using the causal ancestor finding algorithm in Maeda and Shimizu, which is generalized to account for Gaussian disturbances.

Multimodal large language models (MLLMs) have achieved significant success in the general field of image processing. Their emerging task generalization and freeform conversational capabilities can greatly facilitate medical diagnostic assistance, helping patients better understand their conditions and enhancing doctor-patient trust. Computed Tomography (CT) is a non-invasive imaging technique used to capture the internal mechanisms of a patient's condition and is widely utilized. However, in past research, the complex textural features of this imaging data have made accurate interpretation by algorithms challenging, impeding the performance of general LLMs in diagnostic assistance. To address this, we developed OrthoDoc, a MLLM designed for CT diagnostics. OrthoDoc is trained on 120,000 CT images and diagnostic reports and includes a Retrieval-Augmented Generation (RAG) module capable of effectively mitigating model hallucinations. This module is informed by extensive medical literature, textbooks, and explanatory data. Thus, OrthoDoc not only processes complex CT images but also stores, understands, and reasons over medical knowledge and language. In extensive experiments, OrthoDoc outperforms commercial models led by GPT-4, demonstrating superior diagnostic capabilities and accuracy. Specifically, OrthoDoc significantly surpasses existing models in the diagnosis of common orthopedic conditions such as fractures, arthritis, and tumors. Additionally, OrthoDoc exhibits robust generalization and stability when handling rare and complex cases.

Clinical diagnosis is critical in medical practice, typically requiring a continuous and evolving process that includes primary diagnosis, differential diagnosis, and final diagnosis. However, most existing clinical diagnostic tasks are single-step processes, which does not align with the complex multi-step diagnostic procedures found in real-world clinical settings. In this paper, we propose a multi-step diagnostic task and annotate a clinical diagnostic dataset (MSDiagnosis). This dataset includes primary diagnosis, differential diagnosis, and final diagnosis questions. Additionally, we propose a novel and effective framework. This framework combines forward inference, backward inference, reflection, and refinement, enabling the LLM to self-evaluate and adjust its diagnostic results. To assess the effectiveness of our proposed method, we design and conduct extensive experiments. The experimental results demonstrate the effectiveness of the proposed method. We also provide a comprehensive experimental analysis and suggest future research directions for this task.

As the field of artificial intelligence progresses, assistive technologies are becoming more widely used across all industries. The healthcare industry is no different, with numerous studies being done to develop assistive tools for healthcare professionals. Automatic diagnostic systems are one such beneficial tool that can assist with a variety of tasks, including collecting patient information, analyzing test results, and diagnosing patients. However, the idea of developing systems that can provide a differential diagnosis has been largely overlooked in most of these research studies. In this study, we propose a transformer-based approach for providing differential diagnoses based on a patient's age, sex, medical history, and symptoms. We use the DDXPlus dataset, which provides differential diagnosis information for patients based on 49 disease types. Firstly, we propose a method to process the tabular patient data from the dataset and engineer them into patient reports to make them suitable for our research. In addition, we introduce two data modification modules to diversify the training data and consequently improve the robustness of the models. We approach the task as a multi-label classification problem and conduct extensive experiments using four transformer models. All the models displayed promising results by achieving over 97% F1 score on the held-out test set. Moreover, we design additional behavioral tests to get a broader understanding of the models. In particular, for one of our test cases, we prepared a custom test set of 100 samples with the assistance of a doctor. The results on the custom set showed that our proposed data modification modules improved the model's generalization capabilities. We hope our findings will provide future researchers with valuable insights and inspire them to develop reliable systems for automatic differential diagnosis.

False and nuisance alarms in industrial fault detection systems are often triggered by uncertainty, causing normal process variable fluctuations to be erroneously identified as faults. This paper introduces a novel encoder-based residual design that effectively decouples the stochastic and deterministic components of process variables without imposing detection delay. The proposed model employs two distinct encoders to factorize the latent space into two orthogonal spaces: one for the deterministic part and the other for the stochastic part. To ensure the identifiability of the desired spaces, constraints are applied during training. The deterministic space is constrained to be smooth to guarantee determinism, while the stochastic space is required to resemble standard Gaussian noise. Additionally, a decorrelation term enforces the independence of the learned representations. The efficacy of this approach is demonstrated through numerical examples and its application to the Tennessee Eastman process, highlighting its potential for robust fault detection. By focusing decision logic solely on deterministic factors, the proposed model significantly enhances prediction quality while achieving nearly zero false alarms and missed detections, paving the way for improved operational safety and integrity in industrial environments.

Fault detection in automotive engine systems is one of the most promising research areas. Several works have been done in the field of model-based fault diagnosis. Many researchers have discovered more advanced statistical methods and algorithms for better fault detection on any automotive dynamic engine system. The gas turbines/diesel engines produce highly complex and huge data which are highly non-linear. So, researchers should come up with an automated system that is more resilient and robust enough to handle this huge, complex data in highly non-linear dynamic automotive systems. Here, I present an AI-based fault classification and prediction model in the diesel engine that can be applied to any highly non-linear dynamic automotive system. The main contribution of this paper is the AI-based Transformer fault classification and prediction model in the diesel engine concerning the worldwide harmonic light vehicle test procedure (WLTP) driving cycle. This model used 27 input dimensions, 64 hidden dimensions with 2 layers, and 9 heads to create a classifier with 12 output heads (one for fault-free data and 11 different fault types). This model was trained on the UTSA Arc High-Performance Compute (HPC) cluster with 5 NVIDIA V100 GPUs, 40-core CPUs, and 384GB RAM and achieved 70.01 % accuracy on a held test set.

Reinforcement learning techniques leveraging deep learning have made tremendous progress in recent years. However, the complexity of neural networks prevents practitioners from understanding their behavior. Decision trees have gained increased attention in supervised learning for their inherent interpretability, enabling modelers to understand the exact prediction process after learning. This paper considers the problem of optimizing interpretable decision tree policies to replace neural networks in reinforcement learning settings. Previous works have relaxed the tree structure, restricted to optimizing only tree leaves, or applied imitation learning techniques to approximately copy the behavior of a neural network policy with a decision tree. We propose the Decision Tree Policy Optimization (DTPO) algorithm that directly optimizes the complete decision tree using policy gradients. Our technique uses established decision tree heuristics for regression to perform policy optimization. We empirically show that DTPO is a competitive algorithm compared to imitation learning algorithms for optimizing decision tree policies in reinforcement learning.