Knowledge-augmented learning enables the combination of knowledge-based and data-driven approaches. For anomaly detection and diagnosis, understandability is typically an important factor, especially in high-risk areas. Therefore, explainability and interpretability are also major criteria in such contexts. This chapter focuses on knowledge-augmented explainable and interpretable learning to enhance understandability, transparency and ultimately computational sensemaking. We exemplify different approaches and methods in the domains of anomaly detection and diagnosis - from comparatively simple interpretable methods towards more advanced neuro-symbolic approaches.

Recent advancements in Artificial Intelligence (AI), particularly with Large Language Models (LLMs), have led to significant progress in narrow tasks such as image classification, language translation, coding, and writing. However, these models face limitations in reliability and scalability due to their siloed architectures, which are designed to handle only one data modality (data type) at a time. This single modal approach hinders their ability to integrate the complex set of data points required for real-world challenges and problem-solving tasks like medical diagnosis, quality assurance, equipment troubleshooting, and financial decision-making. Addressing these real-world challenges requires a more capable Artificial General Intelligence (AGI) system. Our primary contribution is the development of the Open General Intelligence (OGI) framework, a novel systems architecture that serves as a macro design reference for AGI. The OGI framework adopts a modular approach to the design of intelligent systems, based on the premise that cognition must occur across multiple specialized modules that can seamlessly operate as a single system. OGI integrates these modules using a dynamic processing system and a fabric interconnect, enabling real-time adaptability, multi-modal integration, and scalable processing. The OGI framework consists of three key components: (1) Overall Macro Design Guidance that directs operational design and processing, (2) a Dynamic Processing System that controls routing, primary goals, instructions, and weighting, and (3) Framework Areas, a set of specialized modules that operate cohesively to form a unified cognitive system. By incorporating known principles from human cognition into AI systems, the OGI framework aims to overcome the challenges observed in today's intelligent systems, paving the way for more holistic and context-aware problem-solving capabilities.

This study focuses on Intelligent Fault Diagnosis (IFD) in rotating machinery utilizing a single microphone and a data-driven methodology, effectively diagnosing 42 classes of fault types and severities. The research leverages sound data from the imbalanced MaFaulDa dataset, aiming to strike a balance between high performance and low resource consumption. The testing phase encompassed a variety of configurations, including sampling, quantization, signal normalization, silence removal, Wiener filtering, data scaling, windowing, augmentation, and classifier tuning using XGBoost. Through the analysis of time, frequency, mel-frequency, and statistical features, we achieved an impressive accuracy of 99.54% and an F-Beta score of 99.52% with just 6 boosting trees at an 8 kHz, 8-bit configuration. Moreover, when utilizing only MFCCs along with their first- and second-order deltas, we recorded an accuracy of 97.83% and an F-Beta score of 97.67%. Lastly, by implementing a greedy wrapper approach, we obtained a remarkable accuracy of 96.82% and an F-Beta score of 98.86% using 50 selected features, nearly all of which were first- and second-order deltas of the MFCCs.

Screening questionnaires are used in medicine as a diagnostic aid. Creating them is a long and expensive process, which could potentially be improved through analysis of social media posts related to symptoms and behaviors prior to diagnosis. Here we show a preliminary investigation into the feasibility of generating screening questionnaires for a given medical condition from social media postings. The method first identifies a cohort of relevant users through their posts in dedicated patient groups and a control group of users who reported similar symptoms but did not report being diagnosed with the condition of interest. Posts made prior to diagnosis are used to generate decision rules to differentiate between the different groups, by clustering symptoms mentioned by these users and training a decision tree to differentiate between the two groups. We validate the generated rules by correlating them with scores given by medical doctors to matching hypothetical cases. We demonstrate the proposed method by creating questionnaires for three conditions (endometriosis, lupus, and gout) using the data of several hundreds of users from Reddit. These questionnaires were then validated by medical doctors. The average Pearson's correlation between the latter's scores and the decision rules were 0.58 (endometriosis), 0.40 (lupus) and 0.27 (gout). Our results suggest that the process of questionnaire generation can be, at least partly, automated. These questionnaires are advantageous in that they are based on real-world experience but are currently lacking in their ability to capture the context, duration, and timing of symptoms.

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context demonstrations and those with specialized medical fine-tuning, have demonstrated strong performance in medical language processing but struggle with real-time adaptability, multi-step reasoning, and handling complex medical tasks. Agent-based AI systems address these limitations by incorporating reasoning traces, tool selection based on context, knowledge retrieval, and both short- and long-term memory. These additional features enable the medical AI agent to handle complex medical scenarios where decision-making should be built on real-time interaction with the environment. Therefore, unlike conventional model-based approaches that treat medical queries as isolated questions, medical AI agents approach them as complex tasks and behave more like human doctors. In this paper, we study the choice of the backbone LLM for medical AI agents, which is the foundation for the agent's overall reasoning and action generation. In particular, we consider the emergent o1 model and examine its impact on agents' reasoning, tool-use adaptability, and real-time information retrieval across diverse clinical scenarios, including high-stakes settings such as intensive care units (ICUs). Our findings demonstrate o1's ability to enhance diagnostic accuracy and consistency, paving the way for smarter, more responsive AI tools that support better patient outcomes and decision-making efficacy in clinical practice.

Fault diagnosis technology supports the healthy operation of mechanical equipment. However, the variations conditions during the operation of mechanical equipment lead to significant disparities in data distribution, posing challenges to fault diagnosis. Furthermore, when deploying applications, traditional methods often encounter issues such as latency and data security. Therefore, conducting fault diagnosis and deploying application methods under cross-operating conditions holds significant value. This paper proposes a domain adaptation-based lightweight fault diagnosis framework for edge computing scenarios. Incorporating the local maximum mean discrepancy into knowledge transfer aligns the feature distributions of different domains in a high-dimensional feature space, to discover a common feature space across domains. The acquired fault diagnosis expertise from the cloud-model is transferred to the lightweight edge-model using adaptation knowledge transfer methods. While ensuring real-time diagnostic capabilities, accurate fault diagnosis is achieved across working conditions. We conducted validation experiments on the NVIDIA Jetson Xavier NX kit. In terms of diagnostic performance, the proposed method significantly improved diagnostic accuracy, with average increases of 34.44% and 17.33% compared to the comparison method, respectively. Regarding lightweight effectiveness, proposed method achieved an average inference speed increase of 80.47%. Additionally, compared to the cloud-model, the parameter count of the edge-model decreased by 96.37%, while the Flops decreased by 83.08%.

Chest X-ray imaging is a widely accessible and non-invasive diagnostic tool for detecting thoracic abnormalities. While numerous AI models assist radiologists in interpreting these images, most overlook patients' historical data. To bridge this gap, we introduce Temporal MIMIC dataset, which integrates five years of patient history, including radiographic scans and reports from MIMIC-CXR and MIMIC-IV, encompassing 12,221 patients and thirteen pathologies. Building on this, we present HIST-AID, a framework that enhances automatic diagnostic accuracy using historical reports. HIST-AID emulates the radiologist's comprehensive approach, leveraging historical data to improve diagnostic accuracy. Our experiments demonstrate significant improvements, with AUROC increasing by 6.56% and AUPRC by 9.51% compared to models that rely solely on radiographic scans. These gains were consistently observed across diverse demographic groups, including variations in gender, age, and racial categories. We show that while recent data boost performance, older data may reduce accuracy due to changes in patient conditions. Our work paves the potential of incorporating historical data for more reliable automatic diagnosis, providing critical support for clinical decision-making.

Fault diagnosis is crucial for complex autonomous mobile systems, especially for modern-day autonomous driving (AD). Different actors, numerous use cases, and complex heterogeneous components motivate a fault diagnosis of the system and overall system integrity. AD systems are composed of many heterogeneous components, each with different functionality and possibly using a different algorithm (e.g., rule-based vs. AI components). In addition, these components are subject to the vehicle's driving state and are highly dependent. This paper, therefore, faces this problem by presenting the concept of a modular fault diagnosis framework for AD systems. The concept suggests modular state monitoring and diagnosis elements, together with a state- and dependency-aware aggregation method. Our proposed classification scheme allows for the categorization of the fault diagnosis modules. The concept is implemented on AD shuttle buses and evaluated to demonstrate its capabilities.

Inferring causal relationships in the decision-making processes of machine learning algorithms is a crucial step toward achieving explainable Artificial Intelligence (AI). In this research, we introduce a novel causality measure and a distance metric derived from Lempel-Ziv (LZ) complexity. We explore how the proposed causality measure can be used in decision trees by enabling splits based on features that most strongly \textit{cause} the outcome. We further evaluate the effectiveness of the causality-based decision tree and the distance-based decision tree in comparison to a traditional decision tree using Gini impurity. While the proposed methods demonstrate comparable classification performance overall, the causality-based decision tree significantly outperforms both the distance-based decision tree and the Gini-based decision tree on datasets generated from causal models. This result indicates that the proposed approach can capture insights beyond those of classical decision trees, especially in causally structured data. Based on the features used in the LZ causal measure based decision tree, we introduce a causal strength for each features in the dataset so as to infer the predominant causal variables for the occurrence of the outcome.

Traditional diagnostic methods for these engines predominantly rely on signature analysis, a technique that examines the engine's operational patterns to detect anomalies [1]. While signature analysis has become a de-facto standard due to its effectiveness, it has some substantial limitations, and the growing complexity of modern engines and the vast amounts of data they generate require more advanced and precise diagnostic frameworks [2]. At the same time, machine learning (ML) and artificial intelligence (AI) have emerged as essential tools integrated into various aspects of modern life, from recommendation algorithms [3] to healthcare [4] applications. The potential for advancement and innovation in these fields is immense. Despite this, the application of ML in industrial settings remains underexplored, primarily due to the scarcity of publicly available labeled datasets, especially with malfunctioning engines This lack of data poses significant challenges when transitioning ML solutions from experimental phases to full-scale production, especially given the complexities and variability of real-world conditions [5].