In the context of the health monitoring for the next generation of reusable space launchers, we outline a first step toward developing an onboard fault detection and diagnostic capability for the electrical system that controls the engine valves. Unlike existing approaches in the literature, our solution is designed to meet a broader range of key requirements. This includes estimating confidence levels for predictions, detecting out-of-distribution (OOD) cases, and controlling false alarms. The proposed solution is based on a temporal convolutional autoencoder to automatically extract low-dimensional features from raw sensor data. Fault detection and diagnosis are respectively carried out using a binary and a multiclass classifier trained on the autoencoder latent and residual spaces. The classifiers are histogram-based gradient boosting models calibrated to output probabilities that can be interpreted as confidence levels. A relatively simple technique, based on inductive conformal anomaly detection, is used to identify OOD data. We leverage other simple yet effective techniques, such as cumulative sum control chart (CUSUM) to limit the false alarms, and threshold moving to address class imbalance in fault detection. The proposed framework is highly configurable and has been evaluated on simulated data, covering both nominal and anomalous operational scenarios. The results indicate that our solution is a promising first step, though testing with real data will be necessary to ensure that it achieves the required maturity level for operational use.

Federated Learning (FL) emerged as a solution for collaborative medical image classification while preserving data privacy. However, label noise, which arises from inter-institutional data variability, can cause training instability and degrade model performance. Existing FL methods struggle with noise heterogeneity and the imbalance in medical data. Motivated by these challenges, we propose FedGSCA, a novel framework for enhancing robustness in noisy medical FL. FedGSCA introduces a Global Sample Selector that aggregates noise knowledge from all clients, effectively addressing noise heterogeneity and improving global model stability. Furthermore, we develop a Client Adaptive Adjustment (CAA) mechanism that combines adaptive threshold pseudo-label generation and Robust Credal Labeling Loss. CAA dynamically adjusts to class distributions, ensuring the inclusion of minority samples and carefully managing noisy labels by considering multiple plausible labels. This dual approach mitigates the impact of noisy data and prevents overfitting during local training, which improves the generalizability of the model. We evaluate FedGSCA on one real-world colon slides dataset and two synthetic medical datasets under various noise conditions, including symmetric, asymmetric, extreme, and heterogeneous types. The results show that FedGSCA outperforms the state-of-the-art methods, excelling in extreme and heterogeneous noise scenarios. Moreover, FedGSCA demonstrates significant advantages in improving model stability and handling complex noise, making it well-suited for real-world medical federated learning scenarios.

As machine learning gets adopted into the industry quickly, trustworthiness is increasingly in focus. Yet, efficiency and sustainability of robust training pipelines still have to be established. In this work, we consider a simple pipeline for training adversarially robust decision trees and investigate the efficiency of each step. Our pipeline consists of three stages. Firstly, we choose the perturbation size automatically for each dataset. For that, we introduce a simple algorithm, instead of relying on intuition or prior work. Moreover, we show that the perturbation size can be estimated from smaller models than the one intended for full training, and thus significant gains in efficiency can be achieved. Secondly, we train state-of-the-art adversarial training methods and evaluate them regarding both their training time and adversarial accuracy. Thirdly, we certify the robustness of each of the models thus obtained and investigate the time required for this. We find that verification time, which is critical to the efficiency of the full pipeline, is not correlated with training time.

Cognitive diagnosis (CD) models latent cognitive states of human learners by analyzing their response patterns on diagnostic tests, serving as a crucial machine learning technique for educational assessment and evaluation. Traditional cognitive diagnosis models typically follow a transductive prediction paradigm that optimizes parameters to fit response scores and extract learner abilities. These approaches face significant limitations as they cannot perform instant diagnosis for new learners without computationally expensive retraining and produce diagnostic outputs with limited reliability. In this study, we introduces a novel generative diagnosis paradigm that fundamentally shifts CD from predictive to generative modeling, enabling inductive inference of cognitive states without parameter re-optimization. We propose two simple yet effective instantiations of this paradigm: Generative Item Response Theory (G-IRT) and Generative Neural Cognitive Diagnosis Model (G-NCDM), which achieve excellent performance improvements over traditional methods. The generative approach disentangles cognitive state inference from response prediction through a well-designed generation process that incorporates identifiability and monotonicity conditions. Extensive experiments on real-world datasets demonstrate the effectiveness of our methodology in addressing scalability and reliability challenges, especially $\times 100$ speedup for the diagnosis of new learners. Our framework opens new avenues for cognitive diagnosis applications in artificial intelligence, particularly for intelligent model evaluation and intelligent education systems. The code is available at https://github.com/CSLiJT/Generative-CD.git.

Cyber-attacks jeopardize the safe operation of smart microgrids. At the same time, existing diagnostic methods either depend on expensive multi-point instrumentation or stringent modelling assumptions that are untenable under single-sensor constraints. This paper proposes a Fractional-Order Memory-Enhanced Attack-Diagnosis Scheme (FO-MADS) that achieves low-latency fault localisation and cyber-attack detection using only one VPQ (Voltage-Power-Reactive-power) sensor. FO-MADS first constructs a dual fractional-order feature library by jointly applying Caputo and Grünwald-Letnikov derivatives, thereby amplifying micro-perturbations and slow drifts in the VPQ signal. A two-stage hierarchical classifier then pinpoints the affected inverter and isolates the faulty IGBT switch, effectively alleviating class imbalance. Robustness is further strengthened through Progressive Memory-Replay Adversarial Training (PMR-AT), whose attack-aware loss is dynamically re-weighted via Online Hard Example Mining (OHEM) to prioritise the most challenging samples. Experiments on a four-inverter microgrid testbed comprising 1 normal and 24 fault classes under four attack scenarios demonstrate diagnostic accuracies of 96.6 % (bias), 94.0 % (noise), 92.8 % (data replacement), and 95.7 % (replay), while sustaining 96.7 % under attack-free conditions. These results establish FO-MADS as a cost-effective and readily deployable solution that markedly enhances the cyber-physical resilience of smart microgrids.

The increasing proliferation of vending machines in public and commercial environments has placed a growing emphasis on operational efficiency and customer satisfaction. Traditional maintenance approaches either reactive or time-based preventive are limited in their ability to preempt machine failures, leading to unplanned downtimes and elevated service costs. This research presents a novel predictive maintenance framework tailored for vending machines by leveraging Internet of Things (IoT) sensors and machine learning (ML) algorithms. The proposed system continuously monitors machine components and operating conditions in real time and applies predictive models to forecast failures before they occur. This enables timely maintenance scheduling, minimizing downtime and extending machine lifespan. The framework was validated through simulated fault data and performance evaluation using classification algorithms. Results show a significant improvement in early fault detection and a reduction in redundant service interventions. The findings indicate that predictive maintenance systems, when integrated into vending infrastructure, can transform operational efficiency and service reliability.

The increasing importance of Vision-Based Navigation (VBN) algorithms in space missions raises numerous challenges in ensuring their reliability and operational robustness. Sensor faults can lead to inaccurate outputs from navigation algorithms or even complete data processing faults, potentially compromising mission objectives. Artificial Intelligence (AI) offers a powerful solution for detecting such faults, overcoming many of the limitations associated with traditional fault detection methods. However, the primary obstacle to the adoption of AI in this context is the lack of sufficient and representative datasets containing faulty image data. This study addresses these challenges by focusing on an interplanetary exploration mission scenario. A comprehensive analysis of potential fault cases in camera sensors used within the VBN pipeline is presented. The causes and effects of these faults are systematically characterized, including their impact on image quality and navigation algorithm performance, as well as commonly employed mitigation strategies. To support this analysis, a simulation framework is introduced to recreate faulty conditions in synthetically generated images, enabling a systematic and controlled reproduction of faulty data. The resulting dataset of fault-injected images provides a valuable tool for training and testing AI-based fault detection algorithms. The final link to the dataset will be added after an embargo period. For peer-reviewers, this private link is available.

With the rapid development of more complex robots, Fault Detection and Diagnosis (FDD) becomes increasingly harder. Especially the need for predetermined models and historic data is problematic because they do not encompass the dynamic and fast-changing nature of such systems. To this end, we propose a concept that actively generates a dynamic system model at runtime and utilizes it to locate root causes. The goal is to be applicable to all kinds of robotic systems that share a similar software design. Additionally, it should exhibit minimal overhead and enhance independence from expert attention.

Artificial intelligence holds great promise for expanding access to expert medical knowledge and reasoning. However, most evaluations of language models rely on static vignettes and multiple-choice questions that fail to reflect the complexity and nuance of evidence-based medicine in real-world settings. In clinical practice, physicians iteratively formulate and revise diagnostic hypotheses, adapting each subsequent question and test to what they've just learned, and weigh the evolving evidence before committing to a final diagnosis. To emulate this iterative process, we introduce the Sequential Diagnosis Benchmark, which transforms 304 diagnostically challenging New England Journal of Medicine clinicopathological conference (NEJM-CPC) cases into stepwise diagnostic encounters. A physician or AI begins with a short case abstract and must iteratively request additional details from a gatekeeper model that reveals findings only when explicitly queried. Performance is assessed not just by diagnostic accuracy but also by the cost of physician visits and tests performed. We also present the MAI Diagnostic Orchestrator (MAI-DxO), a model-agnostic orchestrator that simulates a panel of physicians, proposes likely differential diagnoses and strategically selects high-value, cost-effective tests. When paired with OpenAI's o3 model, MAI-DxO achieves 80% diagnostic accuracy--four times higher than the 20% average of generalist physicians. MAI-DxO also reduces diagnostic costs by 20% compared to physicians, and 70% compared to off-the-shelf o3. When configured for maximum accuracy, MAI-DxO achieves 85.5% accuracy. These performance gains with MAI-DxO generalize across models from the OpenAI, Gemini, Claude, Grok, DeepSeek, and Llama families. We highlight how AI systems, when guided to think iteratively and act judiciously, can advance diagnostic precision and cost-effectiveness in clinical care.

Background and Objective: High-throughput multi-omics technologies have proven invaluable for elucidating disease mechanisms and enabling early diagnosis. However, the high cost of multi-omics profiling imposes a significant economic burden, with over reliance on full omics data potentially leading to unnecessary resource consumption. To address these issues, we propose an uncertainty-aware, multi-view dynamic decision framework for omics data classification that aims to achieve high diagnostic accuracy while minimizing testing costs. Methodology: At the single-omics level, we refine the activation functions of neural networks to generate Dirichlet distribution parameters, utilizing subjective logic to quantify both the belief masses and uncertainty mass of classification results. Belief mass reflects the support of a specific omics modality for a disease class, while the uncertainty parameter captures limitations in data quality and model discriminability, providing a more trustworthy basis for decision-making. At the multi omics level, we employ a fusion strategy based on Dempster-Shafer theory to integrate heterogeneous modalities, leveraging their complementarity to boost diagnostic accuracy and robustness. A dynamic decision mechanism is then applied that omics data are incrementally introduced for each patient until either all data sources are utilized or the model confidence exceeds a predefined threshold, potentially before all data sources are utilized. Results and Conclusion: We evaluate our approach on four benchmark multi-omics datasets, ROSMAP, LGG, BRCA, and KIPAN. In three datasets, over 50% of cases achieved accurate classification using a single omics modality, effectively reducing redundant testing. Meanwhile, our method maintains diagnostic performance comparable to full-omics models and preserves essential biological insights.