The in-vivo identification of the kidney stone types during an ureteroscopy would be a major medical advance in urology, as it could reduce the time of the tedious renal calculi extraction process, while diminishing infection risks. Furthermore, such an automated procedure would make possible to prescribe anti-recurrence treatments immediately. Nowadays, only few experienced urologists are able to recognize the kidney stone types in the images of the videos displayed on a screen during the endoscopy. Thus, several deep learning (DL) models have recently been proposed to automatically recognize the kidney stone types using ureteroscopic images. However, these DL models are of black box nature whicl limits their applicability in clinical settings. This contribution proposes a case-based reasoning DL model which uses prototypical parts (PPs) and generates local and global descriptors. The PPs encode for each class (i.e., kidney stone type) visual feature information (hue, saturation, intensity and textures) similar to that used by biologists. The PPs are optimally generated due a new loss function used during the model training. Moreover, the local and global descriptors of PPs allow to explain the decisions ("what" information, "where in the images") in an understandable way for biologists and urologists. The proposed DL model has been tested on a database including images of the six most widespread kidney stone types. The overall average classification accuracy was 90.37. When comparing this results with that of the eight other DL models of the kidney stone state-of-the-art, it can be seen that the valuable gain in explanability was not reached at the expense of accuracy which was even slightly increased with respect to that (88.2) of the best method of the literature. These promising and interpretable results also encourage urologists to put their trust in AI-based solutions.

Molecular sequence analysis is crucial for comprehending several biological processes, including protein-protein interactions, functional annotation, and disease classification. The large number of sequences and the inherently complicated nature of protein structures make it challenging to analyze such data. Finding patterns and enhancing subsequent research requires the use of dimensionality reduction and feature selection approaches. Recently, a method called Correlated Clustering and Projection (CCP) has been proposed as an effective method for biological sequencing data. The CCP technique is still costly to compute even though it is effective for sequence visualization. Furthermore, its utility for classifying molecular sequences is still uncertain. To solve these two problems, we present a Nearest Neighbor Correlated Clustering and Projection (CCP-NN)-based technique for efficiently preprocessing molecular sequence data. To group related molecular sequences and produce representative supersequences, CCP makes use of sequence-to-sequence correlations. As opposed to conventional methods, CCP doesn't rely on matrix diagonalization, therefore it can be applied to a range of machine-learning problems. We estimate the density map and compute the correlation using a nearest-neighbor search technique. We performed molecular sequence classification using CCP and CCP-NN representations to assess the efficacy of our proposed approach. Our findings show that CCP-NN considerably improves classification task accuracy as well as significantly outperforms CCP in terms of computational runtime.

Even though federated learning's potential to overcome Case-based interpretability is vital in explaining medical some of the current AI flaws is currently widely recognized, Artificial Intelligence (AI) model decisions. Generating it also introduces new challenges. The decentralized nature explanations for AI model decisions is paramount to increasing of federated learning guarantees compliance with privacy trust and allowing widespread adoption in clinical regulations but, at the same time, inhibits data access and practice [1]. We can find several approaches to producing inspection [7]. Non-accessible data means that identifying explanations in the scientific literature, from saliency maps bugs or detecting biases is impossible following conventional (highlighting image pixels driving the decision) to textual approaches. The same is true for case-based explainability.

Explainable AI (XAI) can greatly enhance user trust and satisfaction in AI-assisted decision-making processes. Recent findings suggest that a single explainer may not meet the diverse needs of multiple users in an AI system; indeed, even individual users may require multiple explanations. This highlights the necessity for a "multi-shot" approach, employing a combination of explainers to form what we introduce as an "explanation strategy". Tailored to a specific user or a user group, an "explanation experience" describes interactions with personalised strategies designed to enhance their AI decision-making processes. The iSee platform is designed for the intelligent sharing and reuse of explanation experiences, using Case-based Reasoning to advance best practices in XAI. The platform provides tools that enable AI system designers, i.e. design users, to design and iteratively revise the most suitable explanation strategy for their AI system to satisfy end-user needs. All knowledge generated within the iSee platform is formalised by the iSee ontology for interoperability. We use a summative mixed methods study protocol to evaluate the usability and utility of the iSee platform with six design users across varying levels of AI and XAI expertise. Our findings confirm that the iSee platform effectively generalises across applications and its potential to promote the adoption of XAI best practices.

The explainability of black-box machine learning algorithms, commonly known as Explainable Artificial Intelligence (XAI), has become crucial for financial and other regulated industrial applications due to regulatory requirements and the need for transparency in business practices. Among the various paradigms of XAI, Explainable Case-Based Reasoning (XCBR) stands out as a pragmatic approach that elucidates the output of a model by referencing actual examples from the data used to train or test the model. Despite its potential, XCBR has been relatively underexplored for many algorithms such as tree-based models until recently. We start by observing that most XCBR methods are defined based on the distance metric learned by the algorithm. By utilizing a recently proposed technique to extract the distance metric learned by Random Forests (RFs), which is both geometry- and accuracy-preserving, we investigate various XCBR methods. These methods amount to identify special points from the training datasets, such as prototypes, critics, counter-factuals, and semi-factuals, to explain the predictions for a given query of the RF. We evaluate these special points using various evaluation metrics to assess their explanatory power and effectiveness.

Retrieval-Augmented Language Models (RALMs) have significantly improved performance in open-domain question answering (QA) by leveraging external knowledge. However, RALMs still struggle with unanswerable queries, where the retrieved contexts do not contain the correct answer, and with conflicting information, where different sources provide contradictory answers due to imperfect retrieval. This study introduces an in-context learning-based approach to enhance the reasoning capabilities of RALMs, making them more robust in imperfect retrieval scenarios. Our method incorporates Machine Reading Comprehension (MRC) demonstrations, referred to as cases, to boost the model's capabilities to identify unanswerabilities and conflicts among the retrieved contexts. Experiments on two open-domain QA datasets show that our approach increases accuracy in identifying unanswerable and conflicting scenarios without requiring additional fine-tuning. This work demonstrates that in-context learning can Figure 1: Examples of unanswerable and conflict scenario effectively enhance the robustness of RALMs that may arise during retrieval-augmenation.

Multi-Label Text Classification (MLTC) is a practical yet challenging task that involves assigning multiple non-exclusive labels to each document. Previous studies primarily focus on capturing label correlations to assist label prediction by introducing special labeling schemes, designing specific model structures, or adding auxiliary tasks. Recently, the $k$ Nearest Neighbor ($k$NN) framework has shown promise by retrieving labeled samples as references to mine label co-occurrence information in the embedding space. However, two critical biases, namely embedding alignment bias and confidence estimation bias, are often overlooked, adversely affecting prediction performance. In this paper, we introduce a DEbiased Nearest Neighbors (DENN) framework for MLTC, specifically designed to mitigate these biases. To address embedding alignment bias, we propose a debiased contrastive learning strategy, enhancing neighbor consistency on label co-occurrence. For confidence estimation bias, we present a debiased confidence estimation strategy, improving the adaptive combination of predictions from $k$NN and inductive binary classifications. Extensive experiments conducted on four public benchmark datasets (i.e., AAPD, RCV1-V2, Amazon-531, and EUR-LEX57K) showcase the effectiveness of our proposed method. Besides, our method does not introduce any extra parameters.

In the pursuit of enhancing the efficacy and flexibility of interpretable, data-driven classification models, this work introduces a novel incorporation of user-defined preferences with Abstract Argumentation and Case-Based Reasoning (CBR). Specifically, we introduce Preference-Based Abstract Argumentation for Case-Based Reasoning (which we call AA-CBR-P), allowing users to define multiple approaches to compare cases with an ordering that specifies their preference over these comparison approaches. We prove that the model inherently follows these preferences when making predictions and show that previous abstract argumentation for case-based reasoning approaches are insufficient at expressing preferences over constituents of an argument. We then demonstrate how this can be applied to a real-world medical dataset sourced from a clinical trial evaluating differing assessment methods of patients with a primary brain tumour. We show empirically that our approach outperforms other interpretable machine learning models on this dataset.

This work presents a formalization of analogy on numbers that relies on generalized means. It is motivated by recent advances in artificial intelligence and applications of machine learning, where the notion of analogy is used to infer results, create data and even as an assessment tool of object representations, or embeddings, that are basically collections of numbers (vectors, matrices, tensors). This extended analogy use asks for mathematical foundations and clear understanding of the notion of analogy between numbers. We propose a unifying view of analogies that relies on generalized means defined in terms of a power parameter. In particular, we show that any four increasing positive real numbers is an analogy in a unique suitable power. In addition, we show that any such analogy can be reduced to an equivalent arithmetic analogy and that any analogical equation has a solution for increasing numbers, which generalizes without restriction to complex numbers. These foundational results provide a better understanding of analogies in areas where representations are numerical.

This short paper presents preliminary research on the Case-Enhanced Vision Transformer (CEViT), a similarity measurement method aimed at improving the explainability of similarity assessments for image data. Initial experimental results suggest that integrating CEViT into k-Nearest Neighbor (k-NN) classification yields classification accuracy comparable to state-of-the-art computer vision models, while adding capabilities for illustrating differences between classes. CEViT explanations can be influenced by prior cases, to illustrate aspects of similarity relevant to those cases.