This paper introduces UniTranslator, a visionary framework that re-imagines code translation as a collaborative endeavor among multiple, compact LLMs. By orchestrating the interaction of specialized agents, each focused on different aspects of the translation process and grounded in a deep understanding of programming concepts, UniTranslator achieves a level of accuracy and efficiency that rivals larger, monolithic models. Our preliminary evaluation demonstrates the potential of UniTranslator to overcome the limitations of existing approaches and unlock the power of smaller LLMs for complex code translation tasks. We explore the effectiveness of this dynamic multi-agent paradigm in handling diverse language pairs, including low-resource languages, and in mitigating common issues such as code artifacts and hallucinations through the use of Natural Language Inference (NLI) grounding and iterative feedback mechanisms

Order fairness in distributed ledgers refers to properties that relate the order in which transactions are sent or received to the order in which they are eventually finalized, i.e., totally ordered. The study of such properties is relatively new and has been especially stimulated by the rise of Maximal Extractable Value (MEV) attacks in blockchain environments. Indeed, in many classical blockchain protocols, leaders are responsible for selecting the transactions to be included in blocks, which creates a clear vulnerability and opportunity for transaction order manipulation. Unlike blockchains, DAG-based ledgers allow participants in the network to independently propose blocks, which are then arranged as vertices of a directed acyclic graph. Interestingly, leaders in DAG-based ledgers are elected only after the fact, once transactions are already part of the graph, to determine their total order. In other words, transactions are not chosen by single leaders; instead, they are collectively validated by the nodes, and leaders are only elected to establish an ordering. This approach intuitively reduces the risk of transaction manipulation and enhances fairness. In this paper, we aim to quantify the capability of DAG-based ledgers to achieve order fairness. To this end, we define new variants of order fairness adapted to DAG-based ledgers and evaluate the impact of an adversary capable of compromising a limited number of nodes (below the one-third threshold) to reorder transactions. We analyze how often our order fairness properties are violated under different network conditions and parameterizations of the DAG algorithm, depending on the adversary's power. Our study shows that DAG-based ledgers are still vulnerable to reordering attacks, as an adversary can coordinate a minority of Byzantine nodes to manipulate the DAG's structure.

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We introduce a novel distributed source seeking framework, DIAS, designed for multi-robot systems in scenarios where the number of sources is unknown and potentially exceeds the number of robots. Traditional robotic source seeking methods typically focused on directing each robot to a specific strong source and may fall short in comprehensively identifying all potential sources. DIAS addresses this gap by introducing a hybrid controller that identifies the presence of sources and then alternates between exploration for data gathering and exploitation for guiding robots to identified sources. It further enhances search efficiency by dividing the environment into Voronoi cells and approximating source density functions based on Gaussian process regression. Additionally, DIAS can be integrated with existing source seeking algorithms. We compare DIAS with existing algorithms, including DoSS and GMES in simulated gas leakage scenarios where the number of sources outnumbers or is equal to the number of robots. The numerical results show that DIAS outperforms the baseline methods in both the efficiency of source identification by the robots and the accuracy of the estimated environmental density function.

Integration of Vision-Language Models (VLMs) in surgical intelligence is hindered by hallucinations, domain knowledge gaps, and limited understanding of task interdependencies within surgical scenes, undermining clinical reliability. While recent VLMs demonstrate strong general reasoning and thinking capabilities, they still lack the domain expertise and task-awareness required for precise surgical scene interpretation. Although Chain-of-Thought (CoT) can structure reasoning more effectively, current approaches rely on self-generated CoT steps, which often exacerbate inherent domain gaps and hallucinations. To overcome this, we present SurgRAW, a CoT-driven multi-agent framework that delivers transparent, interpretable insights for most tasks in robotic-assisted surgery. By employing specialized CoT prompts across five tasks: instrument recognition, action recognition, action prediction, patient data extraction, and outcome assessment, SurgRAW mitigates hallucinations through structured, domain-aware reasoning. Retrieval-Augmented Generation (RAG) is also integrated to external medical knowledge to bridge domain gaps and improve response reliability. Most importantly, a hierarchical agentic system ensures that CoT-embedded VLM agents collaborate effectively while understanding task interdependencies, with a panel discussion mechanism promotes logical consistency. To evaluate our method, we introduce SurgCoTBench, the first reasoning-based dataset with structured frame-level annotations. With comprehensive experiments, we demonstrate the effectiveness of proposed SurgRAW with 29.32% accuracy improvement over baseline VLMs on 12 robotic procedures, achieving the state-of-the-art performance and advancing explainable, trustworthy, and autonomous surgical assistance.

Multi-agent collaborative perception enhances each agent perceptual capabilities by sharing sensing information to cooperatively perform robot perception tasks. This approach has proven effective in addressing challenges such as sensor deficiencies, occlusions, and long-range perception. However, existing representative collaborative perception systems transmit intermediate feature maps, such as bird-eye view (BEV) representations, which contain a significant amount of non-critical information, leading to high communication bandwidth requirements. To enhance communication efficiency while preserving perception capability, we introduce CoCMT, an object-query-based collaboration framework that optimizes communication bandwidth by selectively extracting and transmitting essential features. Within CoCMT, we introduce the Efficient Query Transformer (EQFormer) to effectively fuse multi-agent object queries and implement a synergistic deep supervision to enhance the positive reinforcement between stages, leading to improved overall performance. Experiments on OPV2V and V2V4Real datasets show CoCMT outperforms state-of-the-art methods while drastically reducing communication needs. On V2V4Real, our model (Top-50 object queries) requires only 0.416 Mb bandwidth, 83 times less than SOTA methods, while improving AP70 by 1.1 percent. This efficiency breakthrough enables practical collaborative perception deployment in bandwidth-constrained environments without sacrificing detection accuracy.

Precision therapeutics require multimodal adaptive models that generate personalized treatment recommendations. We introduce TxAgent, an AI agent that leverages multi-step reasoning and real-time biomedical knowledge retrieval across a toolbox of 211 tools to analyze drug interactions, contraindications, and patient-specific treatment strategies. TxAgent evaluates how drugs interact at molecular, pharmacokinetic, and clinical levels, identifies contraindications based on patient comorbidities and concurrent medications, and tailors treatment strategies to individual patient characteristics. It retrieves and synthesizes evidence from multiple biomedical sources, assesses interactions between drugs and patient conditions, and refines treatment recommendations through iterative reasoning. It selects tools based on task objectives and executes structured function calls to solve therapeutic tasks that require clinical reasoning and cross-source validation. The ToolUniverse consolidates 211 tools from trusted sources, including all US FDA-approved drugs since 1939 and validated clinical insights from Open Targets. TxAgent outperforms leading LLMs, tool-use models, and reasoning agents across five new benchmarks: DrugPC, BrandPC, GenericPC, TreatmentPC, and DescriptionPC, covering 3,168 drug reasoning tasks and 456 personalized treatment scenarios. It achieves 92.1% accuracy in open-ended drug reasoning tasks, surpassing GPT-4o and outperforming DeepSeek-R1 (671B) in structured multi-step reasoning. TxAgent generalizes across drug name variants and descriptions. By integrating multi-step inference, real-time knowledge grounding, and tool-assisted decision-making, TxAgent ensures that treatment recommendations align with established clinical guidelines and real-world evidence, reducing the risk of adverse events and improving therapeutic decision-making.

The necessity of achieving an effective balance between minimizing the losses associated with restricting human mobility and ensuring hospital capacity has gained significant attention in the aftermath of COVID-19. Reinforcement learning (RL)-based strategies for human mobility management have recently advanced in addressing the dynamic evolution of cities and epidemics; however, they still face challenges in achieving coordinated control at the township level and adapting to cities of varying scales. To address the above issues, we propose a multi-agent RL approach that achieves Pareto optimality in managing hospital capacity and human mobility (H2-MARL), applicable across cities of different scales. We first develop a township-level infection model with online-updatable parameters to simulate disease transmission and construct a city-wide dynamic spatiotemporal epidemic simulator. On this basis, H2-MARL is designed to treat each division as an agent, with a trade-off dual-objective reward function formulated and an experience replay buffer enriched with expert knowledge built. To evaluate the effectiveness of the model, we construct a township-level human mobility dataset containing over one billion records from four representative cities of varying scales. Extensive experiments demonstrate that H2-MARL has the optimal dual-objective trade-off capability, which can minimize hospital capacity strain while minimizing human mobility restriction loss. Meanwhile, the applicability of the proposed model to epidemic control in cities of varying scales is verified, which showcases its feasibility and versatility in practical applications.

Ergodic exploration has spawned a lot of interest in mobile robotics due to its ability to design time trajectories that match desired spatial coverage statistics. However, current ergodic approaches are for continuous spaces, which require detailed sensory information at each point and can lead to fractal-like trajectories that cannot be tracked easily. This paper presents a new ergodic approach for graph-based discretization of continuous spaces. It also introduces a new time-discounted ergodicity metric, wherein early visitations of information-rich nodes are weighted more than late visitations. A Markov chain synthesized using a convex program is shown to converge more rapidly to time-discounted ergodicity than the traditional fastest mixing Markov chain. The resultant ergodic traversal method is used within a hierarchical framework for active inspection of confined spaces with the goal of detecting anomalies robustly using SLAM-driven Bayesian hypothesis testing. Both simulation and physical experiments on a ground robot show the advantages of this framework over greedy and random exploration methods for left-behind foreign object debris detection in a ballast tank.

Agent-based modeling is indispensable for studying complex systems across many domains. However, existing simulation platforms exhibit two major issues: performance and modularity. Low performance prevents simulations with a large number of agents, increases development time, limits parameter exploration, and raises computing costs. Inflexible software designs motivate modelers to create their own tools, diverting valuable resources. This dissertation introduces a novel simulation platform called BioDynaMo and its significant improvement, TeraAgent, to alleviate these challenges via three major works. First, we lay the platform's foundation by defining abstractions, establishing software infrastructure, and implementing a multitude of features for agent-based modeling. We demonstrate BioDynaMo's modularity through use cases in neuroscience, epidemiology, and oncology. We validate these models and show the simplicity of adding new functionality with few lines of code. Second, we perform a rigorous performance analysis and identify challenges for shared-memory parallelism. Provided solutions include an optimized grid for neighbor searching, mechanisms to reduce the memory access latency, and exploiting domain knowledge to omit unnecessary work. These improvements yield up to three orders of magnitude speedups, enabling simulations of 1.7 billion agents on a single server. Third, we present TeraAgent, a distributed simulation engine that allows scaling out the computation of one simulation to multiple servers. We identify and address server communication bottlenecks and implement solutions for serialization and delta encoding to accelerate and reduce data transfer. TeraAgent can simulate 500 billion agents and scales to 84096 CPU cores. BioDynaMo has been widely adopted, including a prize-winning radiotherapy simulation recognized as a top 10 breakthrough in physics in 2024.