We present the Methods for Open Agent Systems Evaluation Initiative (MOASEI) Competition, a multi-agent AI benchmarking event designed to evaluate decision-making under open-world conditions. Built on the free-range-zoo environment suite, MOASEI introduced dynamic, partially observable domains with agent and task openness--settings where entities may appear, disappear, or change behavior over time. The 2025 competition featured three tracks--Wildfire, Rideshare, and Cybersecurity--each highlighting distinct dimensions of openness and coordination complexity. Eleven teams from international institutions participated, with four of those teams submitting diverse solutions including graph neural networks, convolutional architectures, predictive modeling, and large language model--driven meta--optimization. Evaluation metrics centered on expected utility, robustness to perturbations, and responsiveness to environmental change. The results reveal promising strategies for generalization and adaptation in open environments, offering both empirical insight and infrastructure for future research. This report details the competition's design, findings, and contributions to the open-agent systems research community.

The emergence of Large Language Models (LLMs) with increasingly sophisticated natural language understanding and generative capabilities has sparked interest in the Agent-based Modelling (ABM) community. With their ability to summarize, generate, analyze, categorize, transcribe and translate text, answer questions, propose explanations, sustain dialogue, extract information from unstructured text, and perform logical reasoning and problem-solving tasks, LLMs have a good potential to contribute to the modelling process. After reviewing the current use of LLMs in ABM, this study reflects on the opportunities and challenges of the potential use of LLMs in ABM. It does so by following the modelling cycle, from problem formulation to documentation and communication of model results, and holding a critical stance.

The deployment of AI models in clinical practice faces a critical challenge: models achieving expert-level performance on benchmarks can fail catastrophically when confronted with real-world variations in medical imaging. Minor shifts in scanner hardware, lighting or demographics can erode accuracy, but currently reliability auditing to identify such catastrophic failure cases before deployment is a bespoke and time-consuming process. Practitioners lack accessible and interpretable tools to expose and repair hidden failure modes. Here we introduce ModelAuditor, a self-reflective agent that converses with users, selects task-specific metrics, and simulates context-dependent, clinically relevant distribution shifts. ModelAuditor then generates interpretable reports explaining how much performance likely degrades during deployment, discussing specific likely failure modes and identifying root causes and mitigation strategies. Our comprehensive evaluation across three real-world clinical scenarios - inter-institutional variation in histopathology, demographic shifts in dermatology, and equipment heterogeneity in chest radiography - demonstrates that ModelAuditor is able correctly identify context-specific failure modes of state-of-the-art models such as the established SIIM-ISIC melanoma classifier. Its targeted recommendations recover 15-25% of performance lost under real-world distribution shift, substantially outperforming both baseline models and state-of-the-art augmentation methods. These improvements are achieved through a multi-agent architecture and execute on consumer hardware in under 10 minutes, costing less than US$0.50 per audit.

Assisting medical students with clinical reasoning (CR) during clinical scenario training remains a persistent challenge in medical education. This paper presents the design and architecture of the Fuzzy Supervisor Agent (FSA), a novel component for the Multi-Agent Educational Clinical Scenario Simulation (MAECSS) platform. The FSA leverages a Fuzzy Inference System (FIS) to continuously interpret student interactions with specialized clinical agents (e.g., patient, physical exam, diagnostic, intervention) using pre-defined fuzzy rule bases for professionalism, medical relevance, ethical behavior, and contextual distraction. By analyzing student decision-making processes in real-time, the FSA is designed to deliver adaptive, context-aware feedback and provides assistance precisely when students encounter difficulties. This work focuses on the technical framework and rationale of the FSA, highlighting its potential to provide scalable, flexible, and human-like supervision in simulation-based medical education. Future work will include empirical evaluation and integration into broader educational settings. More detailed design and implementation is open sourced here.

Recent advances in AI-assisted education have encouraged the integration of vision-language models (VLMs) into academic assessment, particularly for tasks that require both quantitative and qualitative evaluation. However, existing VLM based approaches struggle with complex educational artifacts, such as programming tasks with executable components and measurable outputs, that require structured reasoning and alignment with clearly defined evaluation criteria. We introduce AGACCI, a multi-agent system that distributes specialized evaluation roles across collaborative agents to improve accuracy, interpretability, and consistency in code-oriented assessment. To evaluate the framework, we collected 360 graduate-level code-based assignments from 60 participants, each annotated by domain experts with binary rubric scores and qualitative feedback. Experimental results demonstrate that AGACCI outperforms a single GPT-based baseline in terms of rubric and feedback accuracy, relevance, consistency, and coherence, while preserving the instructional intent and evaluative depth of expert assessments. Although performance varies across task types, AGACCI highlights the potential of multi-agent systems for scalable and context-aware educational evaluation.

The rapid advancements of AI agents have ignited the long-held ambition of leveraging them to accelerate scientific discovery. Achieving this goal requires a deep understanding of the frontiers of human knowledge. As such, Humanity's Last Exam (HLE) provides an exceptionally challenging touchstone for evaluating scientific AI agents. In this work, we aim to construct the foundational architecture for general-purpose agents and validate the capabilities through leading performance on HLE. To achieve this, we introduce X-Master, a tool-augmented reasoning agent designed to emulate human researchers by interacting flexibly with external tools during its reasoning process. This agent, guided by the conceptualization of code as an interaction language, can flexibly leverage built-in Python libraries and our customized tools to augment the reasoning. We further scale its capabilities through X-Masters, a scattered-and-stacked agentic workflow that systematically enhances breadth and depth of reasoning. Our open-source solution, X-Masters, sets a new state-of-the-art record on HLE with a score of 32.1%, surpassing OpenAI's and Google's Deep Research (26.6% and 26.9%) and becoming the first to exceed the 30% threshold. This work allows us to gain a deeper understanding of complex task-solving and accumulates valuable experience that can inform future advancements, guiding subsequent model training.

High-Frequency Trading (HFT) is pivotal in cryptocurrency markets, demanding rapid decision-making. Social media platforms like Reddit offer valuable, yet underexplored, information for such high-frequency, short-term trading. This paper introduces \textbf{PulseReddit}, a novel dataset that is the first to align large-scale Reddit discussion data with high-frequency cryptocurrency market statistics for short-term trading analysis. We conduct an extensive empirical study using Large Language Model (LLM)-based Multi-Agent Systems (MAS) to investigate the impact of social sentiment from PulseReddit on trading performance. Our experiments conclude that MAS augmented with PulseReddit data achieve superior trading outcomes compared to traditional baselines, particularly in bull markets, and demonstrate robust adaptability across different market regimes. Furthermore, our research provides conclusive insights into the performance-efficiency trade-offs of different LLMs, detailing significant considerations for practical model selection in HFT applications. PulseReddit and our findings establish a foundation for advanced MAS research in HFT, demonstrating the tangible benefits of integrating social media.

The increasing deployment of Artificial Intelligence (AI) and other autonomous algorithmic systems presents the world with new systemic risks. While focus often lies on the function of individual algorithms, a critical and underestimated danger arises from their interactions, particularly when algorithmic systems operate without awareness of each other, or when those deploying them are unaware of the full algorithmic ecosystem deployment is occurring in. These interactions can lead to unforeseen, rapidly escalating negative outcomes - from market crashes and energy supply disruptions to potential physical accidents and erosion of public trust - often exceeding the human capacity for effective monitoring and the legal capacities for proper intervention. Current governance frameworks are inadequate as they lack visibility into this complex ecosystem of interactions. This paper outlines the nature of this challenge and proposes some initial policy suggestions centered on increasing transparency and accountability through phased system registration, a licensing framework for deployment, and enhanced monitoring capabilities.

--Traffic congestion remains a major challenge for modern urban transportation, diminishing both efficiency and quality of life. While autonomous driving technologies and reinforcement learning (RL) have shown promise for improving traffic control, most prior work has focused on small-scale networks or isolated intersections. Large-scale mixed traffic control, involving both human-driven and robotic vehicles, remains underexplored. In this study, we propose a decentralized multi-agent reinforcement learning framework for managing large-scale mixed traffic networks, where intersections are controlled either by traditional traffic signals or by robotic vehicles. We evaluate our approach on a real-world network of 14 intersections in Colorado Springs, Colorado, USA, using average vehicle waiting time as the primary measure of traffic efficiency. We are exploring a problem that has not been sufficiently addressed: Is large-scale Multi-Agent Traffic Control (MTC) still feasible when facing time-varying Origin-Destination (OD) patterns?

Cyber-physical systems (CPS) designed in simulators, often consisting of multiple interacting agents (e.g. in multi-agent formations), behave differently in the real-world. We want to verify these systems during runtime when they are deployed. We thus propose robust predictive runtime verification (RPRV) algorithms for: (1) general stochastic CPS under signal temporal logic (STL) tasks, and (2) stochastic multi-agent systems (MAS) under spatio-temporal logic tasks. The RPRV problem presents the following challenges: (1) there may not be sufficient data on the behavior of the deployed CPS, (2) predictive models based on design phase system trajectories may encounter distribution shift during real-world deployment, and (3) the algorithms need to scale to the complexity of MAS and be applicable to spatio-temporal logic tasks. To address the challenges, we assume knowledge of an upper bound on the statistical distance between the trajectory distributions of the system at deployment and design time. We are motivated by our prior work [1, 2] where we proposed an accurate and an interpretable RPRV algorithm for general CPS, which we here extend to the MAS setting and spatio-temporal logic tasks. Specifically, we use a learned predictive model to estimate the system behavior at runtime and robust conformal prediction to obtain probabilistic guarantees by accounting for distribution shifts. Building on [1], we perform robust conformal prediction over the robust semantics of spatio-temporal reach and escape logic (STREL) to obtain centralized RPRV algorithms for MAS. We empirically validate our results in a drone swarm simulator, where we show the scalability of our RPRV algorithms to MAS and analyze the impact of different trajectory predictors on the verification result. To the best of our knowledge, these are the first statistically valid algorithms for MAS under distribution shift.