Recently, game-playing agents based on AI techniques have demonstrated superhuman performance in several sequential games, such as chess, Go, and poker.

Such an allocation is guaranteed to exist [Svensson, 1983].

Such an allocation is guaranteed to exist [ Svensson, 1983 ].

Future autonomous systems promise significant societal benefits, yet their deployment raises concerns about safety and trustworthiness. A key concern is assuring the reliability of robot perception, as perception seeds safe decision-making. Failures in perception are often due to complex yet common environmental factors and can lead to accidents that erode public trust. To address this concern, we introduce the SET (Self, Environment, and Target) Perceptual Factors Framework. We designed the framework to systematically analyze how factors such as weather, occlusion, or sensor limitations negatively impact perception. To achieve this, the framework employs SET State Trees to categorize where such factors originate and SET Factor Trees to model how these sources and factors impact perceptual tasks like object detection or pose estimation. Next, we develop Perceptual Factor Models using both trees to quantify the uncertainty for a given task. Our framework aims to promote rigorous safety assurances and cultivate greater public understanding and trust in autonomous systems by offering a transparent and standardized method for identifying, modeling, and communicating perceptual risks.

Powerful AI tools for drug discovery reside in isolated web apps, desktop programs, and code libraries. Such fragmentation forces scientists to manage incompatible interfaces and specialized scripts, which can be a cumbersome and repetitive process. To address this issue, a Full-pROcess druG dEsign ageNT, named FROGENT, has been proposed. Specifically, FROGENT utilizes a Large Language Model and the Model Context Protocol to integrate multiple dynamic biochemical databases, extensible tool libraries, and task-specific AI models. This agentic framework allows FROGENT to execute complicated drug discovery workflows dynamically, including component tasks such as target identification, molecule generation and retrosynthetic planning. FROGENT has been evaluated on eight benchmarks that cover various aspects of drug discovery, such as knowledge retrieval, property prediction, virtual screening, mechanistic analysis, molecular design, and synthesis. It was compared against six increasingly advanced ReAct-style agents that support code execution and literature searches. Empirical results demonstrated that FROGENT triples the best baseline performance in hit-finding and doubles it in interaction profiling, significantly outperforming both the open-source model Qwen3-32B and the commercial model GPT-4o. In addition, real-world cases have been utilized to validate the practicability and generalization of FROGENT. This development suggests that streamlining the agentic drug discovery pipeline can significantly enhance researcher productivity.

Evaluating graphic designs involves assessing it from multiple facets like alignment, composition, aesthetics and color choices. Evaluating designs in a holistic way involves aggregating feedback from individual expert reviewers. Towards this, we propose an Agentic Design Review System (AgenticDRS), where multiple agents collaboratively analyze a design, orchestrated by a meta-agent. A novel in-context exemplar selection approach based on graph matching and a unique prompt expansion method plays central role towards making each agent design aware. Towards evaluating this framework, we propose DRS-BENCH benchmark. Thorough experimental evaluation against state-of-the-art baselines adapted to the problem setup, backed-up with critical ablation experiments brings out the efficacy of Agentic-DRS in evaluating graphic designs and generating actionable feedback. We hope that this work will attract attention to this pragmatic, yet under-explored research direction.