Automatically determining whether a text and a corresponding image are semantically aligned is a significant challenge for vision-language models, with applications in generative text-to-image and image-to-text tasks. In this work, we study methods for automatic text-image alignment evaluation. We first introduce SeeTRUE: a comprehensive evaluation set, spanning multiple datasets from both text-to-image and image-to-text generation tasks, with human judgements for whether a given text-image pair is semantically aligned. We then describe two automatic methods to determine alignment: the first involving a pipeline based on question generation and visual question answering models, and the second employing an end-to-end classification approach by finetuning multimodal pretrained models. Both methods surpass prior approaches in various text-image alignment tasks, with significant improvements in challenging cases that involve complex composition or unnatural images. Finally, we demonstrate how our approaches can localize specific misalignments between an image and a given text, and how they can be used to automatically re-rank candidates in text-to-image generation.

We present ClinicalTrialsHub, an interactive search-focused platform that consolidates all data from ClinicalTrials.gov and augments it by automatically extracting and structuring trial-relevant information from PubMed research articles. Our system effectively increases access to structured clinical trial data by 83.8% compared to relying on ClinicalTrials.gov alone, with potential to make access easier for patients, clinicians, researchers, and policymakers, advancing evidence-based medicine. ClinicalTrialsHub uses large language models such as GPT-5.1 and Gemini-3-Pro to enhance accessibility. The platform automatically parses full-text research articles to extract structured trial information, translates user queries into structured database searches, and provides an attributed question-answering system that generates evidence-grounded answers linked to specific source sentences. We demonstrate its utility through a user study involving clinicians, clinical researchers, and PhD students of pharmaceutical sciences and nursing, and a systematic automatic evaluation of its information extraction and question answering capabilities.

Longitudinal medical visual question answering (Diff-VQA) requires comparing paired studies from different time points and answering questions about clinically meaningful changes. In this setting, the difference signal and the consistency of visual focus across time are more informative than absolute single-image findings. We propose a saliency-guided encoder-decoder for chest X-ray Diff-VQA that turns post-hoc saliency into actionable supervision. The model first performs a lightweight near-identity affine pre-alignment to reduce nuisance motion between visits. It then executes a within-epoch two-step loop: step 1 extracts a medically relevant keyword from the answer and generates keyword-conditioned Grad-CAM on both images to obtain disease-focused saliency; step 2 applies the shared saliency mask to both time points and generates the final answer. This closes the language-vision loop so that the terms that matter also guide where the model looks, enforcing spatially consistent attention on corresponding anatomy. On Medical-Diff-VQA, the approach attains competitive performance on BLEU, ROUGE-L, CIDEr, and METEOR while providing intrinsic interpretability. Notably, the backbone and decoder are general-domain pretrained without radiology-specific pretraining, highlighting practicality and transferability. These results support saliency-conditioned generation with mild pre-alignment as a principled framework for longitudinal reasoning in medical VQA.

Knowledge Graph Question Answering (KGQA) aims to improve factual accuracy by leveraging structured knowledge. However, real-world Knowledge Graphs (KGs) are often incomplete, leading to the problem of Incomplete KGQA (IKGQA). A common solution is to incorporate external data to fill knowledge gaps, but existing methods lack the capacity to adaptively and contextually fuse multiple sources, failing to fully exploit their complementary strengths. To this end, we propose Debate over Mixed-knowledge (DoM), a novel framework that enables dynamic integration of structured and unstructured knowledge for IKGQA. Built upon the Multi-Agent Debate paradigm, DoM assigns specialized agents to perform inference over knowledge graphs and external texts separately, and coordinates their outputs through iterative interaction. It decomposes the input question into sub-questions, retrieves evidence via dual agents (KG and Retrieval-Augmented Generation, RAG), and employs a judge agent to evaluate and aggregate intermediate answers. This collaboration exploits knowledge complementarity and enhances robustness to KG incompleteness. In addition, existing IKGQA datasets simulate incompleteness by randomly removing triples, failing to capture the irregular and unpredictable nature of real-world knowledge incompleteness. To address this, we introduce a new dataset, Incomplete Knowledge Graph WebQuestions, constructed by leveraging real-world knowledge updates. These updates reflect knowledge beyond the static scope of KGs, yielding a more realistic and challenging benchmark. Through extensive experiments, we show that DoM consistently outperforms state-of-the-art baselines.

Prior work on scientific question answering has largely emphasized chatbot-style systems, with limited exploration of fine-tuning foundation models for domain-specific reasoning. In this study, we developed a chatbot for the University of Limerick's Department of Electronic and Computer Engineering to provide course information to students. A custom dataset of 1,203 question-answer pairs in SQuAD format was constructed using the university book of modules, supplemented with manually and synthetically generated entries. We fine-tuned BERT (Devlin et al., 2019) using PyTorch and evaluated performance with Exact Match and F1 scores. Results show that even modest fine-tuning improves hypothesis framing and knowledge extraction, demonstrating the feasibility of adapting foundation models to educational domains. While domain-specific BERT variants such as BioBERT and SciBERT exist for biomedical and scientific literature, no foundation model has yet been tailored to university course materials. Our work addresses this gap by showing that fine-tuning BERT with academic QA pairs yields effective results, highlighting the potential to scale towards the first domain-specific QA model for universities and enabling autonomous educational knowledge systems.

Recent advances in large language models (LLMs) have transformed open-domain question answering, yet their effectiveness in music-related reasoning remains limited due to sparse music knowledge in pretraining data. While music information retrieval and computational musicology have explored structured and multimodal understanding, few resources support factual and contextual music question answering (MQA) grounded in artist metadata or historical context. We introduce MusWikiDB, a vector database of 3.2M passages from 144K music-related Wikipedia pages, and ArtistMus, a benchmark of 1,000 questions on 500 diverse artists with metadata such as genre, debut year, and topic. These resources enable systematic evaluation of retrieval-augmented generation (RAG) for MQA. Experiments show that RAG markedly improves factual accuracy; open-source models gain up to +56.8 percentage points (for example, Qwen3 8B improves from 35.0 to 91.8), approaching proprietary model performance. RAG-style fine-tuning further boosts both factual recall and contextual reasoning, improving results on both in-domain and out-of-domain benchmarks. MusWikiDB also yields approximately 6 percentage points higher accuracy and 40% faster retrieval than a general-purpose Wikipedia corpus. We release MusWikiDB and ArtistMus to advance research in music information retrieval and domain-specific question answering, establishing a foundation for retrieval-augmented reasoning in culturally rich domains such as music.

In real practice, questions are typically complex and knowledge-intensive, requiring Large Language Models (LLMs) to recognize the multifaceted nature of the question and reason across multiple information sources. Iterative and adaptive retrieval, where LLMs decide when and what to retrieve based on their reasoning, has been shown to be a promising approach to resolve complex, knowledge-intensive questions. However, the performance of such retrieval frameworks is limited by the accumulation of reasoning errors and misaligned retrieval results. To overcome these limitations, we propose TreeRare (Syntax Tree-Guided Retrieval and Reasoning), a framework that utilizes syntax trees to guide information retrieval and reasoning for question answering. Following the principle of compositionality, TreeRare traverses the syntax tree in a bottom-up fashion, and in each node, it generates subcomponent-based queries and retrieves relevant passages to resolve localized uncertainty. A subcomponent question answering module then synthesizes these passages into concise, context-aware evidence. Finally, TreeRare aggregates the evidence across the tree to form a final answer. Experiments across five question answering datasets involving ambiguous or multi-hop reasoning demonstrate that TreeRare achieves substantial improvements over existing state-of-the-art methods.

Domain-specific question answering (QA) systems for services face unique challenges in integrating heterogeneous knowledge sources while ensuring both accuracy and safety. Existing large language models often struggle with factual consistency and context alignment in sensitive domains such as healthcare policies and government welfare. In this work, we introduce Knowledge-Aware Reasoning and Memory-Augmented Adaptation (KARMA), a novel framework designed to enhance QA performance in care scenarios. KARMA incorporates a dual-encoder architecture to fuse structured and unstructured knowledge sources, a gated memory unit to dynamically regulate external knowledge integration, and a safety-aware controllable decoder that mitigates unsafe outputs using safety classification and guided generation techniques. Extensive experiments on a proprietary QA dataset demonstrate that KARMA outperforms strong baselines in both answer quality and safety. This study offers a comprehensive solution for building trustworthy and adaptive QA systems in service contexts.

Climate adaptation strategies are proposed in response to climate change. They are practised in agriculture to sustain food production. These strategies can be found in unstructured data (for example, scientific literature from the Elsevier website) or structured (heterogeneous climate data via government APIs). We present Climate Adaptation question-answering with Improved Readability and Noted Sources (CAIRNS), a framework that enables experts -- farmer advisors -- to obtain credible preliminary answers from complex evidence sources from the web. It enhances readability and citation reliability through a structured ScholarGuide prompt and achieves robust evaluation via a consistency-weighted hybrid evaluator that leverages inter-model agreement with experts. Together, these components enable readable, verifiable, and domain-grounded question-answering without fine-tuning or reinforcement learning. Using a previously reported dataset of expert-curated question-answers, we show that CAIRNS outperforms the baselines on most of the metrics. Our thorough ablation study confirms the results on all metrics. To validate our LLM-based evaluation, we also report an analysis of correlations against human judgment.

Visual understanding requires interpreting both natural scenes and the textual information that appears within them, motivating tasks such as Visual Question Answering (VQA). However, current VQA benchmarks overlook scenarios with visually embedded questions, whereas advanced agents should be able to see the question without separate text input as humans. We introduce Visual-only Question Answering (VoQA), where both the scene and the question appear within a single image, requiring models to perceive and reason purely through vision. This setting supports more realistic visual understanding and interaction in scenarios where questions or instructions are embedded directly in the visual scene. Evaluations under pure visual-only zero-shot, prompt-guided and OCR-assisted settings show that current models exhibit a clear performance drop compared to traditional VQA. To address this, we investigate question-alignment fine-tuning strategies designed to guide models toward interpreting the visual question prior to reasoning. Leveraging VoQA dataset together with these strategies yields robust vision-only reasoning while preserving cross-task generalization to traditional VQA, reflecting the complementary visual and textual reasoning capabilities fostered through VoQA training. The code and data are publicly available.