Large language models (LLMs), such as GPT-4, have demonstrated remarkable capabilities across a wide range of tasks, including health applications. In this paper, we study how LLMs can be used to scale biomedical knowledge curation. We find that while LLMs already possess decent competency in structuring biomedical text, by distillation into a task-specific student model through self-supervised learning, substantial gains can be attained over out-of-box LLMs, with additional advantages such as cost, efficiency, and white-box model access. We conduct a case study on adverse drug event (ADE) extraction, which is an important area for improving care. On standard ADE extraction evaluation, a GPT-3.5 distilled PubMedBERT model attained comparable accuracy as supervised state-of-the-art models without using any labeled data. Despite being over 1,000 times smaller, the distilled model outperformed its teacher GPT-3.5 by over 6 absolute points in F1 and GPT-4 by over 5 absolute points. Ablation studies on distillation model choice (e.g., PubMedBERT vs BioGPT) and ADE extraction architecture shed light on best practice for biomedical knowledge extraction. Similar gains were attained by distillation for other standard biomedical knowledge extraction tasks such as gene-disease associations and protected health information, further illustrating the promise of this approach.

In autonomic computing, self-adaptation has been proposed as a fundamental paradigm to manage the complexity of multiagent systems (MASs). This achieved by extending a system with support to monitor and adapt itself to achieve specific concerns of interest. Communication in these systems is key given that in scenarios involving agent interaction, it enhances cooperation and reduces coordination challenges by enabling direct, clear information exchange. However, improving the expressiveness of the interaction communication with MASs is not without challenges. In this sense, the interplay between self-adaptive systems and effective communication is crucial for future MAS advancements. In this paper, we propose the integration of large language models (LLMs) such as GPT-based technologies into multiagent systems. We anchor our methodology on the MAPE-K model, which is renowned for its robust support in monitoring, analyzing, planning, and executing system adaptations in response to dynamic environments. We also present a practical illustration of the proposed approach, in which we implement and assess a basic MAS-based application. The approach significantly advances the state-of-the-art of self-adaptive systems by proposing a new paradigm for MAS self-adaptation of autonomous systems based on LLM capabilities.

Incremental decision making in real-world environments is one of the most challenging tasks in embodied artificial intelligence. One particularly demanding scenario is Vision and Language Navigation~(VLN) which requires visual and natural language understanding as well as spatial and temporal reasoning capabilities. The embodied agent needs to ground its understanding of navigation instructions in observations of a real-world environment like Street View. Despite the impressive results of LLMs in other research areas, it is an ongoing problem of how to best connect them with an interactive visual environment. In this work, we propose VELMA, an embodied LLM agent that uses a verbalization of the trajectory and of visual environment observations as contextual prompt for the next action. Visual information is verbalized by a pipeline that extracts landmarks from the human written navigation instructions and uses CLIP to determine their visibility in the current panorama view. We show that VELMA is able to successfully follow navigation instructions in Street View with only two in-context examples. We further finetune the LLM agent on a few thousand examples and achieve 25%-30% relative improvement in task completion over the previous state-of-the-art for two datasets.

Large language models (LLMs) demonstrate remarkable ability to comprehend, reason, and generate following nature language instructions. However, the development of LLMs has been primarily focused on high-resource languages, such as English, thereby limiting their applicability and research in other languages. Consequently, we present PolyLM, a multilingual LLM trained on 640 billion (B) tokens, avaliable in two model sizes: 1.7B and 13B. To enhance its multilingual capabilities, we 1) integrate bilingual data into training data; and 2) adopt a curriculum learning strategy that increases the proportion of non-English data from 30% in the first stage to 60% in the final stage during pre-training. Further, we propose a multilingual self-instruct method which automatically generates 132.7K diverse multilingual instructions for model fine-tuning. To assess the model's performance, we collect several existing multilingual tasks, including multilingual understanding, question answering, generation, and translation. Extensive experiments show that PolyLM surpasses other open-source models such as LLaMA and BLOOM on multilingual tasks while maintaining comparable performance in English. Our models, alone with the instruction data and multilingual benchmark, are available at: \url{https://modelscope.cn/models/damo/nlp_polylm_13b_text_generation}.

We investigate the effects of post-training quantization and quantization-aware training on the generalization of Transformer language models. We present a new method called self-distilled quantization (SDQ) that minimizes accumulative quantization errors and outperforms baselines. We apply SDQ to multilingual models XLM-R-Base and InfoXLM-Base and demonstrate that both models can be reduced from 32-bit floating point weights to 8-bit integer weights while maintaining a high level of performance on the XGLUE benchmark. Our results also highlight the challenges of quantizing multilingual models, which must generalize to languages they were not fine-tuned on.

This paper presents "Predictive Pipelined Decoding (PPD)," an approach that speeds up greedy decoding in Large Language Models (LLMs) while maintaining the exact same output as the original decoding. Unlike conventional strategies, PPD employs additional compute resources to parallelize the initiation of subsequent token decoding during the current token decoding. This innovative method reduces decoding latency and reshapes the understanding of trade-offs in LLM decoding strategies. We have developed a theoretical framework that allows us to analyze the trade-off between computation and latency. Using this framework, we can analytically estimate the potential reduction in latency associated with our proposed method, achieved through the assessment of the match rate, represented as p_correct. The results demonstrate that the use of extra computational resources has the potential to accelerate LLM greedy decoding.

We introduce VampNet, a masked acoustic token modeling approach to music synthesis, compression, inpainting, and variation. We use a variable masking schedule during training which allows us to sample coherent music from the model by applying a variety of masking approaches (called prompts) during inference. VampNet is non-autoregressive, leveraging a bidirectional transformer architecture that attends to all tokens in a forward pass. With just 36 sampling passes, VampNet can generate coherent high-fidelity musical waveforms. We show that by prompting VampNet in various ways, we can apply it to tasks like music compression, inpainting, outpainting, continuation, and looping with variation (vamping). Appropriately prompted, VampNet is capable of maintaining style, genre, instrumentation, and other high-level aspects of the music. This flexible prompting capability makes VampNet a powerful music co-creation tool. Code and audio samples are available online.

Adapting pretrained language models to novel domains, such as clinical applications, traditionally involves retraining their entire set of parameters. However, this approach is increasingly proven to be impractical owing to the substantial computational requirements associated with training such large language models. To address this issue, Parameter-Efficient Fine-Tuning (PEFT) techniques offer a viable solution by selectively fine-tuning a small subset of additional parameters, significantly reducing the computational requirements for domain adaptation. In this study, we propose Clinical LLaMA-LoRA, a PEFT adapter layer built upon the open-sourced LLaMA model. Clinical LLaMA-LoRA is trained using clinical notes obtained from the MIMIC-IV database, thereby creating a specialised adapter designed for the clinical domain. Additionally, we propose a two-step PEFT framework which fuses Clinical LLaMA-LoRA with Downstream LLaMA-LoRA, another PEFT adapter specialised for downstream tasks. We evaluate this framework on multiple clinical outcome prediction datasets, comparing it to clinically trained language models. Our proposed framework achieves a state-of-the-art AUROC score averaged across all clinical downstream tasks. We observe substantial improvements of 6-9% AUROC score in the large-scale multilabel classification tasks, such as diagnoses and procedures classification.

Just five months after Anthropic debuted its open-source ChatGPT rival, Claude, the company is back with an updated version that promises longer answers, more detailed reasonings, fewer hallucinations and generally better performance. The updated version, Claude 2, is available today for users in the US and the UK. It can now handle as many as 100,000 tokens -- that's around 75,000 words, or a few hundred pages of documents users can have Claude digest and analyze -- up significantly from the previous version's 9,000 token limit. In AI, tokens are the bits and pieces that your input prompt gets broken down into so that the model can more readily process them -- hence Claude's ability to "digest" user data. This increased capacity will also translate into longer, more nuanced responses. Claude 2 will even be able to generate short stories "up to a few thousand tokens," the company announced.

In May, I was confronted with a robot version of my writer self. It was made, at my request, by a Silicon Valley startup called Writer, which specializes in building artificial-intelligence tools that produce content in the voice of a particular brand or institution. In my case, it was meant to replicate my personal writing voice. Whereas a model like OpenAI's ChatGPT is "trained" on millions of words from across the Internet, Robot Kyle runs on Writer's bespoke model with an extra layer of training, based on some hundred and fifty thousand words of my writing alone. Writer's pitch is that I, Human Kyle, can use Robot Kyle to generate text in a style that sounds like mine, at a speed that I could only dream of.