Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Recently, Large Language Models (LLMs) have emerged as general-purpose models with the ability to process complex information and produce human-quality text, presenting a wealth of potential applications in healthcare. Directly applying LLMs in clinical settings is not straightforward, with LLMs susceptible to providing inconsistent or nonsensical answers. We describe how LLM-based systems can utilize external tools to provide a novel interface between clinicians and digital technologies. This enhances the utility and practical impact of digital healthcare tools and AI models while addressing current issues with using LLM in clinical settings such as hallucinations. We illustrate LLM-based interfaces with examples from cardiovascular disease and diabetes risk prediction, highlighting the benefit compared to traditional interfaces for digital tools.

In the rapidly evolving landscape of education, digital technologies have repeatedly disrupted traditional pedagogical methods. This paper explores the latest of these disruptions: the potential integration of large language models (LLMs) and chatbots into graduate engineering education. We begin by tracing historical and technological disruptions to provide context and then introduce key terms such as machine learning and deep learning and the underlying mechanisms of recent advancements, namely attention/transformer models and graphics processing units. The heart of our investigation lies in the application of an LLM-based chatbot in a graduate fluid mechanics course. We developed a question bank from the course material and assessed the chatbot's ability to provide accurate, insightful responses. The results are encouraging, demonstrating not only the bot's ability to effectively answer complex questions but also the potential advantages of chatbot usage in the classroom, such as the promotion of self-paced learning, the provision of instantaneous feedback, and the reduction of instructors' workload. The study also examines the transformative effect of intelligent prompting on enhancing the chatbot's performance. Furthermore, we demonstrate how powerful plugins like Wolfram Alpha for mathematical problem-solving and code interpretation can significantly extend the chatbot's capabilities, transforming it into a comprehensive educational tool. While acknowledging the challenges and ethical implications surrounding the use of such AI models in education, we advocate for a balanced approach. The use of LLMs and chatbots in graduate education can be greatly beneficial but requires ongoing evaluation and adaptation to ensure ethical and efficient use.

Social media sites have become a popular platform for individuals to seek and share health information. Despite the progress in natural language processing for social media mining, a gap remains in analyzing health-related texts on social discourse in the context of events. Event-driven analysis can offer insights into different facets of healthcare at an individual and collective level, including treatment options, misconceptions, knowledge gaps, etc. This paper presents a paradigm to characterize health-related information-seeking in social discourse through the lens of events. Events here are board categories defined with domain experts that capture the trajectory of the treatment/medication. To illustrate the value of this approach, we analyze Reddit posts regarding medications for Opioid Use Disorder (OUD), a critical global health concern. To the best of our knowledge, this is the first attempt to define event categories for characterizing information-seeking in OUD social discourse. Guided by domain experts, we develop TREAT-ISE, a novel multilabel treatment information-seeking event dataset to analyze online discourse on an event-based framework. This dataset contains Reddit posts on information-seeking events related to recovery from OUD, where each post is annotated based on the type of events. We also establish a strong performance benchmark (77.4% F1 score) for the task by employing several machine learning and deep learning classifiers. Finally, we thoroughly investigate the performance and errors of ChatGPT on this task, providing valuable insights into the LLM's capabilities and ongoing characterization efforts.

Model editing techniques modify a minor proportion of knowledge in Large Language Models (LLMs) at a relatively low cost, which have demonstrated notable success. Existing methods assume Transformer Layer (TL) hidden states are values of key-value memories of the Feed-Forward Network (FFN). They usually optimize the TL hidden states to memorize target knowledge and use it to update the weights of the FFN in LLMs. However, the information flow of TL hidden states comes from three parts: Multi-Head Self-Attention (MHSA), FFN, and residual connections. Existing methods neglect the fact that the TL hidden states contains information not specifically required for FFN. Consequently, the performance of model editing decreases. To achieve more precise model editing, we analyze hidden states of MHSA and FFN, finding that MHSA encodes certain general knowledge extraction patterns. This implies that MHSA weights do not require updating when new knowledge is introduced. Based on above findings, we introduce PMET, which simultaneously optimizes Transformer Component (TC, namely MHSA and FFN) hidden states, while only using the optimized TC hidden states of FFN to precisely update FFN weights. Our experiments demonstrate that PMET exhibits state-of-the-art performance on both the COUNTERFACT and zsRE datasets. Our ablation experiments substantiate the effectiveness of our enhancements, further reinforcing the finding that the MHSA encodes certain general knowledge extraction patterns and indicating its storage of a small amount of factual knowledge. Our code is available at https://github.com/xpq-tech/PMET.

Large Language Models (LLMs) have demonstrated impressive capabilities in creative tasks such as storytelling and E-mail generation. However, as LLMs are primarily trained on final text results rather than intermediate revisions, it might be challenging for them to perform text rewriting tasks. Most studies in the rewriting tasks focus on a particular transformation type within the boundaries of single sentences. In this work, we develop new strategies for instruction tuning and reinforcement learning to better align LLMs for cross-sentence rewriting tasks using diverse wording and structures expressed through natural languages including 1) generating rewriting instruction data from Wiki edits and public corpus through instruction generation and chain-of-thought prompting; 2) collecting comparison data for reward model training through a new ranking function. To facilitate this research, we introduce OpenRewriteEval, a novel benchmark covers a wide variety of rewriting types expressed through natural language instructions. Our results show significant improvements over a variety of baselines. The public repository is available on GitHub under Google Research (https://github.com/google-research/google-research/tree/master/rewritelm).

Contrastive vision-language representation learning has achieved state-of-the-art performance for zero-shot classification, by learning from millions of image-caption pairs crawled from the internet. However, the massive data that powers large multimodal models such as CLIP, makes them extremely vulnerable to various types of targeted data poisoning and backdoor attacks. Despite this vulnerability, robust contrastive vision-language pre-training against such attacks has remained unaddressed. In this work, we propose ROCLIP, the first effective method for robust pre-training multimodal vision-language models against targeted data poisoning and backdoor attacks. ROCLIP effectively breaks the association between poisoned image-caption pairs by considering a relatively large and varying pool of random captions, and matching every image with the text that is most similar to it in the pool instead of its own caption, every few epochs.It also leverages image and text augmentations to further strengthen the defense and improve the performance of the model. Our extensive experiments show that ROCLIP renders state-of-the-art targeted data poisoning and backdoor attacks ineffective during pre-training CLIP models. In particular, ROCLIP decreases the success rate for targeted data poisoning attacks from 93.75% to 12.5% and that of backdoor attacks down to 0%, while improving the model's linear probe performance by 10% and maintains a similar zero shot performance compared to CLIP. By increasing the frequency of matching, ROCLIP is able to defend strong attacks, which add up to 1% poisoned examples to the data, and successfully maintain a low attack success rate of 12.5%, while trading off the performance on some tasks.

Events describe happenings in our world that are of importance. Naturally, understanding events mentioned in multimedia content and how they are related forms an important way of comprehending our world. Existing literature can infer if events across textual and visual (video) domains are identical (via grounding) and thus, on the same semantic level. However, grounding fails to capture the intricate cross-event relations that exist due to the same events being referred to on many semantic levels. For example, in Figure 1, the abstract event of "war" manifests at a lower semantic level through subevents "tanks firing" (in video) and airplane "shot" (in text), leading to a hierarchical, multimodal relationship between the events. In this paper, we propose the task of extracting event hierarchies from multimodal (video and text) data to capture how the same event manifests itself in different modalities at different semantic levels. This reveals the structure of events and is critical to understanding them. To support research on this task, we introduce the Multimodal Hierarchical Events (MultiHiEve) dataset. Unlike prior video-language datasets, MultiHiEve is composed of news video-article pairs, which makes it rich in event hierarchies. We densely annotate a part of the dataset to construct the test benchmark. We show the limitations of state-of-the-art unimodal and multimodal baselines on this task. Further, we address these limitations via a new weakly supervised model, leveraging only unannotated video-article pairs from MultiHiEve. We perform a thorough evaluation of our proposed method which demonstrates improved performance on this task and highlight opportunities for future research.

The ability of large language models (LLMs) to process visual inputs has given rise to general-purpose vision systems, unifying various vision-language (VL) tasks by instruction tuning. However, due to the enormous diversity in input-output formats in the vision domain, existing general-purpose models fail to successfully integrate segmentation and multi-image inputs with coarse-level tasks into a single framework. In this work, we introduce VistaLLM, a powerful visual system that addresses coarse- and fine-grained VL tasks over single and multiple input images using a unified framework. VistaLLM utilizes an instruction-guided image tokenizer that filters global embeddings using task descriptions to extract compressed and refined features from numerous images. Moreover, VistaLLM employs a gradient-aware adaptive sampling technique to represent binary segmentation masks as sequences, significantly improving over previously used uniform sampling. To bolster the desired capability of VistaLLM, we curate CoinIt, a comprehensive coarse-to-fine instruction tuning dataset with 6.8M samples. We also address the lack of multi-image grounding datasets by introducing a novel task, AttCoSeg (Attribute-level Co-Segmentation), which boosts the model's reasoning and grounding capability over multiple input images. Extensive experiments on a wide range of V- and VL tasks demonstrate the effectiveness of VistaLLM by achieving consistent state-of-the-art performance over strong baselines across all downstream tasks. Our project page can be found at https://shramanpramanick.github.io/VistaLLM/.

Content warning: This paper contains examples of harmful language. With the recent surge in popularity of LLMs has come an ever-increasing need for LLM safety training. In this paper, we investigate the fragility of SOTA opensource LLMs under simple, optimization-free attacks we refer to as priming attacks, which are easy to execute and effectively bypass alignment from safety training. Our proposed attack improves the Attack Success Rate on Harmful Behaviors, as measured by Llama Guard, by up to 3.3 compared to baselines. Autoregressive Large Language Models (LLMs) have emerged as powerful conversational agents widely used in user-facing applications. To ensure that LLMs cannot be used for nefarious purposes, they are extensively safety-trained for human alignment using techniques such as RLHF (Christiano et al., 2023). Despite such efforts, it is still possible to circumvent the alignment to obtain harmful outputs (Carlini et al., 2023). For instance, Zou et al. (2023) generated prompts to attack popular open-source aligned LLMs such as Llama-2 (Touvron et al., 2023a) and Vicuna (Chiang et al., 2023) to either output harmful target strings or comply with harmful behavior requests.

Instruction-tuned large language models have shown remarkable performance in aligning generated text with user intentions across various tasks. However, maintaining human-like discourse structure in the generated text remains a challenging research question. In this paper, we propose Instruct-SCTG, a flexible and effective sequential framework that harnesses instruction-tuned language models to generate structurally coherent text in both fine-tuned and zero-shot setups. Our framework generates articles in a section-by-section manner, aligned with the desired human structure using natural language instructions. Furthermore, we introduce a new automatic metric that measures discourse divergence in a fuzzy manner. Extensive experiments on three datasets from representative domains of news and recipes demonstrate the state-of-the-art performance of our framework in imposing discourse structure during text generation, as verified by both automatic and human evaluation. Our code will be available on Github.