Scientific publishing lays the foundation of science by disseminating research findings, fostering collaboration, encouraging reproducibility, and ensuring that scientific knowledge is accessible, verifiable, and built upon over time. Recently, there has been immense speculation about how many people are using large language models (LLMs) like ChatGPT in their academic writing, and to what extent this tool might have an effect on global scientific practices. However, we lack a precise measure of the proportion of academic writing substantially modified or produced by LLMs. To address this gap, we conduct the first systematic, large-scale analysis across 950,965 papers published between January 2020 and February 2024 on the arXiv, bioRxiv, and Nature portfolio journals, using a population-level statistical framework to measure the prevalence of LLM-modified content over time. Our statistical estimation operates on the corpus level and is more robust than inference on individual instances. Our findings reveal a steady increase in LLM usage, with the largest and fastest growth observed in Computer Science papers (up to 17.5%). In comparison, Mathematics papers and the Nature portfolio showed the least LLM modification (up to 6.3%). Moreover, at an aggregate level, our analysis reveals that higher levels of LLM-modification are associated with papers whose first authors post preprints more frequently, papers in more crowded research areas, and papers of shorter lengths. Our findings suggests that LLMs are being broadly used in scientific writings.

Classroom observation protocols standardize the assessment of teaching effectiveness and facilitate comprehension of classroom interactions. Whereas these protocols offer teachers specific feedback on their teaching practices, the manual coding by human raters is resource-intensive and often unreliable. This has sparked interest in developing AI-driven, cost-effective methods for automating such holistic coding. Our work explores a multimodal approach to automatically estimating encouragement and warmth in classrooms, a key component of the Global Teaching Insights (GTI) study's observation protocol. To this end, we employed facial and speech emotion recognition with sentiment analysis to extract interpretable features from video, audio, and transcript data. The prediction task involved both classification and regression methods. Additionally, in light of recent large language models' remarkable text annotation capabilities, we evaluated ChatGPT's zero-shot performance on this scoring task based on transcripts. We demonstrated our approach on the GTI dataset, comprising 367 16-minute video segments from 92 authentic lesson recordings. The inferences of GPT-4 and the best-trained model yielded correlations of r = .341 and r = .441 with human ratings, respectively. Combining estimates from both models through averaging, an ensemble approach achieved a correlation of r = .513, comparable to human inter-rater reliability. Our model explanation analysis indicated that text sentiment features were the primary contributors to the trained model's decisions. Moreover, GPT-4 could deliver logical and concrete reasoning as potential teacher guidelines. Our findings provide insights into using advanced, multimodal techniques for automated classroom observation, aiming to foster teacher training through frequent and valuable feedback.

Large Language Models (LLMs) have demonstrated impressive and diverse abilities that can benefit various domains, such as zero and few-shot information extraction from clinical text without domain-specific training. However, for the ICD coding task, they often hallucinate key details and produce high recall but low precision results due to the high-dimensional and skewed distribution of the ICD codes. Existing LLM-based methods fail to account for the complex and dynamic interactions among the human agents involved in coding, such as patients, physicians, and coders, and they lack interpretability and reliability. In this paper, we present a novel multi-agent method for ICD coding, which mimics the real-world coding process with five agents: a patient agent, a physician agent, a coder agent, a reviewer agent, and an adjuster agent. Each agent has a specific function and uses a LLM-based model to perform it. We evaluate our method on the MIMIC-III dataset and show that our proposed multi-agent coding framework substantially improves performance on both common and rare codes compared to Zero-shot Chain of Thought (CoT) prompting and self-consistency with CoT. The ablation study confirms the proposed agent roles' efficacy. Our method also matches the state-of-the-art ICD coding methods that require pre-training or fine-tuning, in terms of coding accuracy, rare code accuracy, and explainability.

Reinforcement learning with human feedback for aligning large language models (LLMs) trains a reward model typically using ranking loss with comparison pairs. However, the training procedure suffers from an inherent problem: the uncontrolled scaling of reward scores during reinforcement learning due to the lack of constraints while training the reward model. This paper proposes a Prior Constraints-based Reward Model (PCRM) training method to mitigate this problem. PCRM incorporates prior constraints--specifically, length ratio and cosine similarity between outputs of each comparison pair--during reward model training to regulate optimization magnitude and control score margins. We comprehensively evaluate PCRM by examining its rank correlation with human preferences and its effectiveness in aligning LLMs via RL. Experimental results demonstrate that PCRM significantly improves alignment performance by effectively constraining reward score scaling. As another bonus, our method is easily integrated into arbitrary rank-based alignment methods, such as direct preference optimization, and can yield consistent improvement. The code is available at https://github.com/wangclnlp/

Recent advances in large language models (LLMs) have enhanced their ability to process long input contexts. This development is particularly crucial for tasks that involve retrieving knowledge from an external datastore, which can result in long inputs. However, recent studies show a positional bias in LLMs, demonstrating varying performance depending on the location of useful information within the input sequence. In this study, we conduct extensive experiments to investigate the root causes of positional bias. Our findings indicate that the primary contributor to LLM positional bias stems from the inherent positional preferences of different models. We demonstrate that merely employing prompt-based solutions is inadequate for overcoming the positional preferences. To address this positional bias issue of a pre-trained LLM, we developed a Position-Aware Parameter Efficient Fine-Tuning (PAPEFT) approach which is composed of a data augmentation technique and a parameter efficient adapter, enhancing a uniform attention distribution across the input context. Our experiments demonstrate that the proposed approach effectively reduces positional bias, improving LLMs' effectiveness in handling long context sequences for various tasks that require externally retrieved knowledge.

The escalating demand to migrate legacy software across different Instruction Set Architectures (ISAs) has driven the development of assembly-to-assembly translators to map between their respective assembly languages. However, the development of these tools requires substantial engineering effort. State-of-the-art approaches use lifting, a technique where source assembly code is translated to an architecture-independent intermediate representation (IR) (for example, the LLVM IR) and use a pre-existing compiler to recompile the IR to the target ISA. However, the hand-written rules these lifters employ are sensitive to the particular compiler and optimization level used to generate the code and require significant engineering effort to support each new ISA. We propose Forklift, the first neural lifter that learns how to translate assembly to LLVM IR using a token-level encoder-decoder Transformer. We show how to incrementally add support to new ISAs by fine tuning the assembly encoder and freezing the IR decoder, improving the overall accuracy and efficiency. We collect millions of parallel LLVM IR, x86, ARM, and RISC-V programs across compilers and optimization levels to train Forklift and set up an input/output-based accuracy harness. We evaluate Forklift on two challenging benchmark suites and translate 2.5x more x86 programs than a state-of-the-art hand-written lifter and 4.4x more x86 programs than GPT-4 as well as enabling translation from new ISAs.

The ability to interact with machines using natural human language is becoming not just commonplace, but expected. The next step is not just text interfaces, but speech interfaces and not just with computers, but with all machines including robots. In this paper, we chronicle the recent history of this growing field of spoken dialogue with robots and offer the community three proposals, the first focused on education, the second on benchmarks, and the third on the modeling of language when it comes to spoken interaction with robots. The three proposals should act as white papers for any researcher to take and build upon.

Language models (LMs) have greatly propelled the research on natural language processing. However, LMs also raise concerns regarding the generation of biased or toxic content and the potential disclosure of private information from the training dataset. In this work, we present a new efficient approach, Ethos, that rectifies LMs to mitigate toxicity and bias in outputs and avoid privacy leakage. Ethos is built on task arithmetic. However, unlike current task arithmetic algorithms, Ethos distinguishes general beneficial and undesired knowledge when reconstructing task vectors. Specifically, Ethos first obtains a set of principal components from the pre-trained models using singular value decomposition. Then, by projecting the task vector onto principal components, Ethos identifies the principal components that encode general or undesired knowledge. Ethos performs negating using the task vector with undesired knowledge only, thereby minimizing collateral damage on general model utility. We demonstrate the efficacy of our approach on three different tasks: debiasing, detoxification, and memorization unlearning. Evaluations show Ethos is more effective in removing undesired knowledge and maintaining the overall model performance compared to current task arithmetic methods.

Large language models (LLMs) have gained widespread interest due to their ability to process human language and perform tasks on which they have not been explicitly trained. This is relevant for the chemical sciences, which face the problem of small and diverse datasets that are frequently in the form of text. LLMs have shown promise in addressing these issues and are increasingly being harnessed to predict chemical properties, optimize reactions, and even design and conduct experiments autonomously. However, we still have only a very limited systematic understanding of the chemical reasoning capabilities of LLMs, which would be required to improve models and mitigate potential harms. Here, we introduce "ChemBench," an automated framework designed to rigorously evaluate the chemical knowledge and reasoning abilities of state-of-the-art LLMs against the expertise of human chemists. We curated more than 7,000 question-answer pairs for a wide array of subfields of the chemical sciences, evaluated leading open and closed-source LLMs, and found that the best models outperformed the best human chemists in our study on average. The models, however, struggle with some chemical reasoning tasks that are easy for human experts and provide overconfident, misleading predictions, such as about chemicals' safety profiles. These findings underscore the dual reality that, although LLMs demonstrate remarkable proficiency in chemical tasks, further research is critical to enhancing their safety and utility in chemical sciences. Our findings also indicate a need for adaptations to chemistry curricula and highlight the importance of continuing to develop evaluation frameworks to improve safe and useful LLMs.

Large language models (LLMs) are great at processing multiple natural language processing tasks, but their abilities are constrained by inferior performance with long context, slow inference speed, and the high cost of computing the results. Deploying LLMs with precise and informative context helps users process large-scale datasets more effectively and cost-efficiently. Existing works rely on compressing long prompt contexts into soft prompts. However, soft prompt compression encounters limitations in transferability across different LLMs, especially API-based LLMs. To this end, this work aims to compress lengthy prompts in the form of natural language with LLM transferability. This poses two challenges: (i) Natural Language (NL) prompts are incompatible with back-propagation, and (ii) NL prompts lack flexibility in imposing length constraints. In this work, we propose a Natural Language Prompt Encapsulation (Nano-Capsulator) framework compressing original prompts into NL formatted Capsule Prompt while maintaining the prompt utility and transferability. Specifically, to tackle the first challenge, the Nano-Capsulator is optimized by a reward function that interacts with the proposed semantics preserving loss. To address the second question, the Nano-Capsulator is optimized by a reward function featuring length constraints. Experimental results demonstrate that the Capsule Prompt can reduce 81.4% of the original length, decrease inference latency up to 4.5x, and save 80.1% of budget overheads while providing transferability across diverse LLMs and different datasets.