The adoption of large language models (LLMs) in healthcare has attracted significant research interest. However, their performance in healthcare remains under-investigated and potentially limited, due to i) they lack rich domain-specific knowledge and medical reasoning skills; and ii) most state-of-the-art LLMs are unimodal, text-only models that cannot directly process multimodal inputs. To this end, we propose a multimodal medical collaborative reasoning framework \textbf{MultiMedRes}, which incorporates a learner agent to proactively gain essential information from domain-specific expert models, to solve medical multimodal reasoning problems. Our method includes three steps: i) \textbf{Inquire}: The learner agent first decomposes given complex medical reasoning problems into multiple domain-specific sub-problems; ii) \textbf{Interact}: The agent then interacts with domain-specific expert models by repeating the ``ask-answer'' process to progressively obtain different domain-specific knowledge; iii) \textbf{Integrate}: The agent finally integrates all the acquired domain-specific knowledge to accurately address the medical reasoning problem. We validate the effectiveness of our method on the task of difference visual question answering for X-ray images. The experiments demonstrate that our zero-shot prediction achieves state-of-the-art performance, and even outperforms the fully supervised methods. Besides, our approach can be incorporated into various LLMs and multimodal LLMs to significantly boost their performance.

In-context learning has been extensively validated in large language models. However, the mechanism and selection strategy for in-context example selection, which is a crucial ingredient in this approach, lacks systematic and in-depth research. In this paper, we propose a data compression approach to the selection of in-context examples. We introduce a two-stage method that can effectively choose relevant examples and retain sufficient information about the training dataset within the in-context examples. Our method shows a significant improvement of an average of 5.90% across five different real-world datasets using four language models.

We present RALL-E, a robust language modeling method for text-to-speech (TTS) synthesis. While previous work based on large language models (LLMs) shows impressive performance on zero-shot TTS, such methods often suffer from poor robustness, such as unstable prosody (weird pitch and rhythm/duration) and a high word error rate (WER), due to the autoregressive prediction style of language models. The core idea behind RALL-E is chain-of-thought (CoT) prompting, which decomposes the task into simpler steps to enhance the robustness of LLM-based TTS. To accomplish this idea, RALL-E first predicts prosody features (pitch and duration) of the input text and uses them as intermediate conditions to predict speech tokens in a CoT style. Second, RALL-E utilizes the predicted duration prompt to guide the computing of self-attention weights in Transformer to enforce the model to focus on the corresponding phonemes and prosody features when predicting speech tokens. Results of comprehensive objective and subjective evaluations demonstrate that, compared to a powerful baseline method VALL-E, RALL-E significantly improves the WER of zero-shot TTS from $5.6\%$ (without reranking) and $1.7\%$ (with reranking) to $2.5\%$ and $1.0\%$, respectively. Furthermore, we demonstrate that RALL-E correctly synthesizes sentences that are hard for VALL-E and reduces the error rate from $68\%$ to $4\%$.

Adapting large language models (LLMs) to unseen tasks with in-context training samples without fine-tuning remains an important research problem. To learn a robust LLM that adapts well to unseen tasks, multiple meta-training approaches have been proposed such as MetaICL and MetaICT, which involve meta-training pre-trained LLMs on a wide variety of diverse tasks. These meta-training approaches essentially perform in-context multi-task fine-tuning and evaluate on a disjointed test set of tasks. Even though they achieve impressive performance, their goal is never to compute a truly general set of parameters. In this paper, we propose MAML-en-LLM, a novel method for meta-training LLMs, which can learn truly generalizable parameters that not only perform well on disjointed tasks but also adapts to unseen tasks. We see an average increase of 2% on unseen domains in the performance while a massive 4% improvement on adaptation performance. Furthermore, we demonstrate that MAML-en-LLM outperforms baselines in settings with limited amount of training data on both seen and unseen domains by an average of 2%. Finally, we discuss the effects of type of tasks, optimizers and task complexity, an avenue barely explored in meta-training literature. Exhaustive experiments across 7 task settings along with two data settings demonstrate that models trained with MAML-en-LLM outperform SOTA meta-training approaches.

We explore the usage of large language models (LLM) in human-in-the-loop human-in-the-plant cyber-physical systems (CPS) to translate a high-level prompt into a personalized plan of actions, and subsequently convert that plan into a grounded inference of sequential decision-making automated by a real-world CPS controller to achieve a control goal. We show that it is relatively straightforward to contextualize an LLM so it can generate domain-specific plans. However, these plans may be infeasible for the physical system to execute or the plan may be unsafe for human users. To address this, we propose CPS-LLM, an LLM retrained using an instruction tuning framework, which ensures that generated plans not only align with the physical system dynamics of the CPS but are also safe for human users. The CPS-LLM consists of two innovative components: a) a liquid time constant neural network-based physical dynamics coefficient estimator that can derive coefficients of dynamical models with some unmeasured state variables; b) the model coefficients are then used to train an LLM with prompts embodied with traces from the dynamical system and the corresponding model coefficients. We show that when the CPS-LLM is integrated with a contextualized chatbot such as BARD it can generate feasible and safe plans to manage external events such as meals for automated insulin delivery systems used by Type 1 Diabetes subjects.

Numerous studies on adversarial attacks targeting self-driving policies fail to incorporate realistic-looking adversarial objects, limiting real-world applicability. Building upon prior research that facilitated the transition of adversarial objects from simulations to practical applications, this paper discusses a modified gradient-based texture optimization method to discover realistic-looking adversarial objects. While retaining the core architecture and techniques of the prior research, the proposed addition involves an entity termed the 'Judge'. This agent assesses the texture of a rendered object, assigning a probability score reflecting its realism. This score is integrated into the loss function to encourage the NeRF object renderer to concurrently learn realistic and adversarial textures. The paper analyzes four strategies for developing a robust 'Judge': 1) Leveraging cutting-edge vision-language models. 2) Fine-tuning open-sourced vision-language models. 3) Pretraining neurosymbolic systems. 4) Utilizing traditional image processing techniques. Our findings indicate that strategies 1) and 4) yield less reliable outcomes, pointing towards strategies 2) or 3) as more promising directions for future research.

Text classification is a crucial and fundamental task in natural language processing. Compared with the previous learning paradigm of pre-training and fine-tuning by cross entropy loss, the recently proposed supervised contrastive learning approach has received tremendous attention due to its powerful feature learning capability and robustness. Although several studies have incorporated this technique for text classification, some limitations remain. First, many text datasets are imbalanced, and the learning mechanism of supervised contrastive learning is sensitive to data imbalance, which may harm the model performance. Moreover, these models leverage separate classification branch with cross entropy and supervised contrastive learning branch without explicit mutual guidance. To this end, we propose a novel model named SharpReCL for imbalanced text classification tasks. First, we obtain the prototype vector of each class in the balanced classification branch to act as a representation of each class. Then, by further explicitly leveraging the prototype vectors, we construct a proper and sufficient target sample set with the same size for each class to perform the supervised contrastive learning procedure. The empirical results show the effectiveness of our model, which even outperforms popular large language models across several datasets.

Content-based recommendation systems play a crucial role in delivering personalized content to users in the digital world. In this work, we introduce EmbSum, a novel framework that enables offline pre-computations of users and candidate items while capturing the interactions within the user engagement history. By utilizing the pretrained encoder-decoder model and poly-attention layers, EmbSum derives User Poly-Embedding (UPE) and Content Poly-Embedding (CPE) to calculate relevance scores between users and candidate items. EmbSum actively learns the long user engagement histories by generating user-interest summary with supervision from large language model (LLM). The effectiveness of EmbSum is validated on two datasets from different domains, surpassing state-of-the-art (SoTA) methods with higher accuracy and fewer parameters. Additionally, the model's ability to generate summaries of user interests serves as a valuable by-product, enhancing its usefulness for personalized content recommendations.

Large Language Model (LLM) -in-the-loop applications have been shown to effectively interpret the human user's commands, make plans, and operate external tools/systems accordingly. Still, the operation scope of the LLM agent is limited to passively following the user, requiring the user to frame his/her needs with regard to the underlying tools/systems. We note that the potential of an LLM-Agent User Interface (LAUI) is much greater. A user mostly ignorant to the underlying tools/systems should be able to work with a LAUI to discover an emergent workflow. Contrary to the conventional way of designing an explorable GUI to teach the user a predefined set of ways to use the system, in the ideal LAUI, the LLM agent is initialized to be proficient with the system, proactively studies the user and his/her needs, and proposes new interaction schemes to the user. To illustrate LAUI, we present Flute X GPT, a concrete example using an LLM agent, a prompt manager, and a flute-tutoring multi-modal software-hardware system to facilitate the complex, real-time user experience of learning to play the flute.

Transformers have a remarkable ability to learn and execute tasks based on examples provided within the input itself, without explicit prior training. It has been argued that this capability, known as in-context learning (ICL), is a cornerstone of Transformers' success, yet questions about the necessary sample complexity, pretraining task diversity, and context length for successful ICL remain unresolved. Here, we provide a precise answer to these questions in an exactly solvable model of ICL of a linear regression task by linear attention. We derive sharp asymptotics for the learning curve in a phenomenologically-rich scaling regime where the token dimension is taken to infinity; the context length and pretraining task diversity scale proportionally with the token dimension; and the number of pretraining examples scales quadratically. We demonstrate a double-descent learning curve with increasing pretraining examples, and uncover a phase transition in the model's behavior between low and high task diversity regimes: In the low diversity regime, the model tends toward memorization of training tasks, whereas in the high diversity regime, it achieves genuine in-context learning and generalization beyond the scope of pretrained tasks. These theoretical insights are empirically validated through experiments with both linear attention and full nonlinear Transformer architectures.