A key concern with the concept of "alignment" is the implicit question of "alignment to what?". AI systems are increasingly used across the world, yet safety alignment is often focused on homogeneous monolingual settings. Additionally, preference training and safety measures often overfit to harms common in Western-centric datasets. Here, we explore the viability of different alignment approaches when balancing dual objectives: addressing and optimizing for a non-homogeneous set of languages and cultural preferences while minimizing both global and local harms. We collect the first set of human annotated red-teaming prompts in different languages distinguishing between global and local harm, which serve as a laboratory for understanding the reliability of alignment techniques when faced with preference distributions that are non-stationary across geographies and languages. While this setting is seldom covered by the literature to date, which primarily centers on English harm mitigation, it captures real-world interactions with AI systems around the world. We establish a new precedent for state-of-the-art alignment techniques across 6 languages with minimal degradation in general performance. Our work provides important insights into cross-lingual transfer and novel optimization approaches to safeguard AI systems designed to serve global populations.

We present seven experiments exploring gender biases in GPT. Initially, GPT was asked to generate demographics of a potential writer of twenty phrases containing feminine stereotypes and twenty with masculine stereotypes. Results show a strong asymmetry, with stereotypically masculine sentences attributed to a female more often than vice versa. For example, the sentence "I love playing fotbal! Im practicing with my cosin Michael" was constantly assigned by ChatGPT to a female writer. This phenomenon likely reflects that while initiatives to integrate women in traditionally masculine roles have gained momentum, the reverse movement remains relatively underdeveloped. Subsequent experiments investigate the same issue in high-stakes moral dilemmas. GPT-4 finds it more appropriate to abuse a man to prevent a nuclear apocalypse than to abuse a woman. This bias extends to other forms of violence central to the gender parity debate (abuse), but not to those less central (torture). Moreover, this bias increases in cases of mixed-sex violence for the greater good: GPT-4 agrees with a woman using violence against a man to prevent a nuclear apocalypse but disagrees with a man using violence against a woman for the same purpose. Finally, these biases are implicit, as they do not emerge when GPT-4 is directly asked to rank moral violations. These results highlight the necessity of carefully managing inclusivity efforts to prevent unintended discrimination.

Recent studies have demonstrated that large language models (LLMs) are susceptible to being misled by false premise questions (FPQs), leading to errors in factual knowledge, know as factuality hallucination. Existing benchmarks that assess this vulnerability primarily rely on manual construction, resulting in limited scale and lack of scalability. In this work, we introduce an automated, scalable pipeline to create FPQs based on knowledge graphs (KGs). The first step is modifying true triplets extracted from KGs to create false premises. Subsequently, utilizing the stateof-the-art capabilities of GPTs, we generate semantically rich FPQs. Based on the proposed method, we present a comprehensive benchmark, the Knowledge Graph-based False Premise Questions (KG-FPQ), which contains approximately 178k FPQs across three knowledge domains, at six levels of confusability, and in two task formats. Using KG-FPQ, we conduct extensive evaluations on several representative LLMs and provide valuable insights. The KG-FPQ dataset and code are available Figure 1: Top: LLM correctly answers when faced with at https://github.com/yanxuzhu/KG-FPQ. a TPQ. Middle: LLM experiences factuality hallucination when faced with a FPQ.

The parallels between protein sequences and natural language in their sequential structures have inspired the application of large language models (LLMs) to protein understanding. Despite the success of LLMs in NLP, their effectiveness in comprehending protein sequences remains an open question, largely due to the absence of datasets linking protein sequences to descriptive text. Researchers have then attempted to adapt LLMs for protein understanding by integrating a protein sequence encoder with a pre-trained LLM. However, this adaptation raises a fundamental question: "Can LLMs, originally designed for NLP, effectively comprehend protein sequences as a form of language?" Current datasets fall short in addressing this question due to the lack of a direct correlation between protein sequences and corresponding text descriptions, limiting the ability to train and evaluate LLMs for protein understanding effectively. To bridge this gap, we introduce ProteinLMDataset, a dataset specifically designed for further self-supervised pretraining and supervised fine-tuning (SFT) of LLMs to enhance their capability for protein sequence comprehension. Specifically, ProteinLMDataset includes 17.46 billion tokens for pretraining and 893,000 instructions for SFT. Additionally, we present ProteinLMBench, the first benchmark dataset consisting of 944 manually verified multiple-choice questions for assessing the protein understanding capabilities of LLMs. ProteinLMBench incorporates protein-related details and sequences in multiple languages, establishing a new standard for evaluating LLMs' abilities in protein comprehension. The large language model InternLM2-7B, pretrained and fine-tuned on the ProteinLMDataset, outperforms GPT-4 on ProteinLMBench, achieving the highest accuracy score.

Previous works on Large Language Models (LLMs) have mainly focused on evaluating their helpfulness or harmlessness. However, honesty, another crucial alignment criterion, has received relatively less attention. Dishonest behaviors in LLMs, such as spreading misinformation and defrauding users, present severe risks that intensify as these models approach superintelligent levels. Enhancing honesty in LLMs addresses critical limitations and helps uncover latent capabilities that are not readily expressed. This underscores the urgent need for reliable methods and benchmarks to effectively ensure and evaluate the honesty of LLMs. In this paper, we introduce BeHonest, a pioneering benchmark specifically designed to assess honesty in LLMs comprehensively. BeHonest evaluates three essential aspects of honesty: awareness of knowledge boundaries, avoidance of deceit, and consistency in responses. Building on this foundation, we designed 10 scenarios to evaluate and analyze 9 popular LLMs on the market, including both closed-source and open-source models from different model families with varied model sizes. Our findings indicate that there is still significant room for improvement in the honesty of LLMs. We encourage the AI community to prioritize honesty alignment in these models, which can harness their full potential to benefit society while preventing them from causing harm through deception or inconsistency. Our benchmark and code can be found at: \url{https://github.com/GAIR-NLP/BeHonest}.

Test-time interventions for language models can enhance factual accuracy, mitigate harmful outputs, and improve model efficiency without costly retraining. But despite a flood of new methods, different types of interventions are largely developing independently. In practice, multiple interventions must be applied sequentially to the same model, yet we lack standardized ways to study how interventions interact. We fill this gap by introducing composable interventions, a framework to study the effects of using multiple interventions on the same language models, featuring new metrics and a unified codebase. Using our framework, we conduct extensive experiments and compose popular methods from three emerging intervention categories -- Knowledge Editing, Model Compression, and Machine Unlearning. Our results from 310 different compositions uncover meaningful interactions: compression hinders editing and unlearning, composing interventions hinges on their order of application, and popular general-purpose metrics are inadequate for assessing composability. Taken together, our findings showcase clear gaps in composability, suggesting a need for new multi-objective interventions. All of our code is public: https://github.com/hartvigsen-group/composable-interventions.

Medical images and radiology reports are crucial for diagnosing medical conditions, highlighting the importance of quantitative analysis for clinical decision-making. However, the diversity and cross-source heterogeneity of these data challenge the generalizability of current data-mining methods. Multimodal large language models (MLLMs) have recently transformed many domains, significantly affecting the medical field. Notably, Gemini-Vision-series (Gemini) and GPT-4-series (GPT-4) models have epitomized a paradigm shift in Artificial General Intelligence (AGI) for computer vision, showcasing their potential in the biomedical domain. In this study, we evaluated the performance of the Gemini, GPT-4, and 4 popular large models for an exhaustive evaluation across 14 medical imaging datasets, including 5 medical imaging categories (dermatology, radiology, dentistry, ophthalmology, and endoscopy), and 3 radiology report datasets. The investigated tasks encompass disease classification, lesion segmentation, anatomical localization, disease diagnosis, report generation, and lesion detection. Our experimental results demonstrated that Gemini-series models excelled in report generation and lesion detection but faces challenges in disease classification and anatomical localization. Conversely, GPT-series models exhibited proficiency in lesion segmentation and anatomical localization but encountered difficulties in disease diagnosis and lesion detection. Additionally, both the Gemini series and GPT series contain models that have demonstrated commendable generation efficiency. While both models hold promise in reducing physician workload, alleviating pressure on limited healthcare resources, and fostering collaboration between clinical practitioners and artificial intelligence technologies, substantial enhancements and comprehensive validations remain imperative before clinical deployment.

Large language models (LLMs) often exhibit undesirable behaviors, such as hallucinations and sequence repetitions. We propose to view these behaviors as fallbacks that models exhibit under uncertainty, and investigate the connection between them. We categorize fallback behaviors -- sequence repetitions, degenerate text, and hallucinations -- and extensively analyze them in models from the same family that differ by the amount of pretraining tokens, parameter count, or the inclusion of instruction-following training. Our experiments reveal a clear and consistent ordering of fallback behaviors, across all these axes: the more advanced an LLM is (i.e., trained on more tokens, has more parameters, or instruction-tuned), its fallback behavior shifts from sequence repetitions, to degenerate text, and then to hallucinations. Moreover, the same ordering is observed throughout a single generation, even for the best-performing models; as uncertainty increases, models shift from generating hallucinations to producing degenerate text and then sequence repetitions. Lastly, we demonstrate that while common decoding techniques, such as random sampling, might alleviate some unwanted behaviors like sequence repetitions, they increase harder-to-detect hallucinations.

Large vision language models (LVLMs) often suffer from object hallucination, producing objects not present in the given images. While current benchmarks for object hallucination primarily concentrate on the presence of a single object class rather than individual entities, this work systematically investigates multi-object hallucination, examining how models misperceive (e.g., invent nonexistent objects or become distracted) when tasked with focusing on multiple objects simultaneously. We introduce Recognition-based Object Probing Evaluation (ROPE), an automated evaluation protocol that considers the distribution of object classes within a single image during testing and uses visual referring prompts to eliminate ambiguity. With comprehensive empirical studies and analysis of potential factors leading to multi-object hallucination, we found that (1) LVLMs suffer more hallucinations when focusing on multiple objects compared to a single object. (2) The tested object class distribution affects hallucination behaviors, indicating that LVLMs may follow shortcuts and spurious correlations.(3) Hallucinatory behaviors are influenced by data-specific factors, salience and frequency, and model intrinsic behaviors. We hope to enable LVLMs to recognize and reason about multiple objects that often occur in realistic visual scenes, provide insights, and quantify our progress towards mitigating the issues.

Southeast Asia (SEA) is a region rich in linguistic diversity and cultural variety, with over 1,300 indigenous languages and a population of 671 million people. However, prevailing AI models suffer from a significant lack of representation of texts, images, and audio datasets from SEA, compromising the quality of AI models for SEA languages. Evaluating models for SEA languages is challenging due to the scarcity of high-quality datasets, compounded by the dominance of English training data, raising concerns about potential cultural misrepresentation. To address these challenges, we introduce SEACrowd, a collaborative initiative that consolidates a comprehensive resource hub that fills the resource gap by providing standardized corpora in nearly 1,000 SEA languages across three modalities. Through our SEACrowd benchmarks, we assess the quality of AI models on 36 indigenous languages across 13 tasks, offering valuable insights into the current AI landscape in SEA. Furthermore, we propose strategies to facilitate greater AI advancements, maximizing potential utility and resource equity for the future of AI in SEA.