Large Language Models (LLMs) have emerged as promising solutions for a variety of medical and clinical decision support applications. However, LLMs are often subject to different types of biases, which can lead to unfair treatment of individuals, worsening health disparities, and reducing trust in AI-augmented medical tools. Aiming to address this important issue, in this study, we present a new model alignment approach for aligning LLMs using a preference optimization method within a knowledge distillation framework. Prior to presenting our proposed method, we first use an evaluation framework to conduct a comprehensive (largest to our knowledge) empirical evaluation to reveal the type and nature of existing biases in LLMs used for medical applications. We then offer a bias mitigation technique to reduce the unfair patterns in LLM outputs across different subgroups identified by the protected attributes. We show that our mitigation method is effective in significantly reducing observed biased patterns. Our code is publicly available at \url{https://github.com/healthylaife/FairAlignmentLLM}.

Automated unit test generators, particularly search-based software testing tools like EvoSuite, are capable of generating tests with high coverage. Although these generators alleviate the burden of writing unit tests, they often pose challenges for software engineers in terms of understanding the generated tests. To address this, we introduce UTGen, which combines search-based software testing and large language models to enhance the understandability of automatically generated test cases. We achieve this enhancement through contextualizing test data, improving identifier naming, and adding descriptive comments. Through a controlled experiment with 32 participants from both academia and industry, we investigate how the understandability of unit tests affects a software engineer's ability to perform bug-fixing tasks. We selected bug-fixing to simulate a real-world scenario that emphasizes the importance of understandable test cases. We observe that participants working on assignments with UTGen test cases fix up to 33% more bugs and use up to 20% less time when compared to baseline test cases. From the post-test questionnaire, we gathered that participants found that enhanced test names, test data, and variable names improved their bug-fixing process.

Safety alignment is indispensable for Large language models (LLMs) to defend threats from malicious instructions. However, recent researches reveal safety-aligned LLMs prone to reject benign queries due to the exaggerated safety issue, limiting their helpfulness. In this paper, we propose a Safety-Conscious Activation Steering (SCANS) method to mitigate the exaggerated safety concerns in aligned LLMs. First, SCANS extracts the refusal steering vectors within the activation space and utilizes vocabulary projection to anchor some specific safety-critical layers which influence model refusal behavior. Second, by tracking the hidden state transition, SCANS identifies the steering direction and steers the model behavior accordingly, achieving a balance between exaggerated safety and adequate safety. Experiments show that SCANS achieves new state-of-the-art performance on XSTest and OKTest benchmarks, without impairing their defense capability against harmful queries and maintaining almost unchanged model capability.

With the burgeoning advancements in the field of natural language processing (NLP), the demand for training data has increased significantly. To save costs, it has become common for users and businesses to outsource the labor-intensive task of data collection to third-party entities. Unfortunately, recent research has unveiled the inherent risk associated with this practice, particularly in exposing NLP systems to potential backdoor attacks. Specifically, these attacks enable malicious control over the behavior of a trained model by poisoning a small portion of the training data. Unlike backdoor attacks in computer vision, textual backdoor attacks impose stringent requirements for attack stealthiness. However, existing attack methods meet significant trade-off between effectiveness and stealthiness, largely due to the high information entropy inherent in textual data. In this paper, we introduce the Efficient and Stealthy Textual backdoor attack method, EST-Bad, leveraging Large Language Models (LLMs). Our EST-Bad encompasses three core strategies: optimizing the inherent flaw of models as the trigger, stealthily injecting triggers with LLMs, and meticulously selecting the most impactful samples for backdoor injection. Through the integration of these techniques, EST-Bad demonstrates an efficient achievement of competitive attack performance while maintaining superior stealthiness compared to prior methods across various text classifier datasets.

Breast ultrasound is essential for detecting and diagnosing abnormalities, with radiology reports summarizing key findings like lesion characteristics and malignancy assessments. Extracting this critical information is challenging due to the unstructured nature of these reports, with varied linguistic styles and inconsistent formatting. While proprietary LLMs like GPT-4 are effective, they are costly and raise privacy concerns when handling protected health information. This study presents a pipeline for developing an in-house LLM to extract clinical information from radiology reports. We first use GPT-4 to create a small labeled dataset, then fine-tune a Llama3-8B model on it. Evaluated on clinician-annotated reports, our model achieves an average F1 score of 84.6%, which is on par with GPT-4. Our findings demonstrate the feasibility of developing an in-house LLM that not only matches GPT-4's performance but also offers cost reductions and enhanced data privacy.

In human reading and communication, individuals tend to engage in geospatial reasoning, which involves recognizing geographic entities and making informed inferences about their interrelationships. To mimic such cognitive process, current methods either utilize conventional natural language understanding toolkits, or directly apply models pretrained on geo-related natural language corpora. However, these methods face two significant challenges: i) they do not generalize well to unseen geospatial scenarios, and ii) they overlook the importance of integrating geospatial context from geographical databases with linguistic information from the Internet. To handle these challenges, we propose GeoReasoner, a language model capable of reasoning on geospatially grounded natural language. Specifically, it first leverages Large Language Models (LLMs) to generate a comprehensive location description based on linguistic and geospatial information. It also encodes direction and distance information into spatial embedding via treating them as pseudo-sentences. Consequently, the model is trained on both anchor-level and neighbor-level inputs to learn geo-entity representation. Extensive experimental results demonstrate GeoReasoner's superiority in three tasks: toponym recognition, toponym linking, and geo-entity typing, compared to the state-of-the-art baselines.

In-context learning (ICL) has proven to be an effective strategy for improving the performance of large language models (LLMs) with no additional training. However, the exact mechanism behind these performance improvements remains unclear. This study is the first to show how ICL surfaces memorized training data and to explore the correlation between this memorization and performance across various ICL regimes: zero-shot, few-shot, and many-shot. Our most notable findings include: (1) ICL significantly surfaces memorization compared to zero-shot learning in most cases; (2) demonstrations, without their labels, are the most effective element in surfacing memorization; (3) ICL improves performance when the surfaced memorization in few-shot regimes reaches a high level (about 40%); and (4) there is a very strong correlation between performance and memorization in ICL when it outperforms zero-shot learning. Overall, our study uncovers a hidden phenomenon -- memorization -- at the core of ICL, raising an important question: to what extent do LLMs truly generalize from demonstrations in ICL, and how much of their success is due to memorization?

Deliberation involves participants exchanging knowledge, arguments, and perspectives and has been shown to be effective at addressing polarization. The Stanford Online Deliberation Platform facilitates large-scale deliberations. It enables video-based online discussions on a structured agenda for small groups without requiring human moderators. This paper's data comes from various deliberation events, including one conducted in collaboration with Meta in 32 countries, and another with 38 post-secondary institutions in the US. Estimating the quality of contributions in a conversation is crucial for assessing feature and intervention impacts. Traditionally, this is done by human annotators, which is time-consuming and costly. We use a large language model (LLM) alongside eight human annotators to rate contributions based on justification, novelty, expansion of the conversation, and potential for further expansion, with scores ranging from 1 to 5. Annotators also provide brief justifications for their ratings. Using the average rating from other human annotators as the ground truth, we find the model outperforms individual human annotators. While pairs of human annotators outperform the model in rating justification and groups of three outperform it on all four metrics, the model remains competitive. We illustrate the usefulness of the automated quality rating by assessing the effect of nudges on the quality of deliberation. We first observe that individual nudges after prolonged inactivity are highly effective, increasing the likelihood of the individual requesting to speak in the next 30 seconds by 65%. Using our automated quality estimation, we show that the quality ratings for statements prompted by nudging are similar to those made without nudging, signifying that nudging leads to more ideas being generated in the conversation without losing overall quality.

Open-Vocab 3D Instance Segmentation methods (OV-3DIS) have recently demonstrated their ability to generalize to unseen objects. However, these methods still depend on predefined class names during testing, restricting the autonomy of agents. To mitigate this constraint, we propose a novel problem termed Open-Ended 3D Instance Segmentation (OE-3DIS), which eliminates the necessity for predefined class names during testing. Moreover, we contribute a comprehensive set of strong baselines, derived from OV-3DIS approaches and leveraging 2D Multimodal Large Language Models. To assess the performance of our OE-3DIS system, we introduce a novel Open-Ended score, evaluating both the semantic and geometric quality of predicted masks and their associated class names, alongside the standard AP score. Our approach demonstrates significant performance improvements over the baselines on the ScanNet200 and ScanNet++ datasets. Remarkably, our method surpasses the performance of Open3DIS, the current state-of-the-art method in OV-3DIS, even in the absence of ground-truth object class names.

With the development of the modern social economy, tourism has become an important way to meet people's spiritual needs, bringing development opportunities to the tourism industry. However, existing large language models (LLMs) face challenges in personalized recommendation capabilities and the generation of content that can sometimes produce hallucinations. This study proposes an optimization scheme for Tibet tourism LLMs based on retrieval-augmented generation (RAG) technology. By constructing a database of tourist viewpoints and processing the data using vectorization techniques, we have significantly improved retrieval accuracy. The application of RAG technology effectively addresses the hallucination problem in content generation. The optimized model shows significant improvements in fluency, accuracy, and relevance of content generation. This research demonstrates the potential of RAG technology in the standardization of cultural tourism information and data analysis, providing theoretical and technical support for the development of intelligent cultural tourism service systems.