Large Language Model
Enhancing LLMs for Impression Generation in Radiology Reports through a Multi-Agent System
Zeng, Fang, Lyu, Zhiliang, Li, Quanzheng, Li, Xiang
In radiology workflow, radiologists traditionally interpret imaging studies and manually draft detailed reports, including an "impression" section that summarizes clinically significant findings and possible diagnosis, which is a vital part of the report for referring physicians and patient care. This process is time-consuming and subject to variability impacted by the radiologist's knowledge and experience [1]. Automated impression generation has the potential to improve report consistency, reduce radiologist workload, and enhance the overall quality of radiology reports [2]. Such a feature is especially needed with the recent growth in the demands for medical imaging, which are straining radiologists, leading to possible burnout and impacting their ability to provide timely and precise reports [3]. Large Language Models (LLMs) have shown exceptional capabilities in understanding and generating text that is coherent and contextually relevant, making them promising tools for auto-generating impressions from findings in radiology reports. A few studies have investigated LLMs' ability for the impression summarization task [2, 4, 5, 6, 7, 8], demonstrating the potential of LLMs to revolutionize radiology workflow by automating the report generation process. Various techniques, such as prompt engineering, model fine-tuning, and retrieval-augmented generation (RAG) [6], have been used to improve their performance and mitigate the limitations of LLMs, including hallucinations and insufficient domain knowledge. However, current approaches often lack the ability to integrate these techniques together within a unified framework and the scalability to incorporate new techniques and/or requirements in impression generation.
A Survey of Sustainability in Large Language Models: Applications, Economics, and Challenges
Singh, Aditi, Patel, Nirmal Prakashbhai, Ehtesham, Abul, Kumar, Saket, Khoei, Tala Talaei
Large Language Models (LLMs) have transformed numerous domains by providing advanced capabilities in natural language understanding, generation, and reasoning. Despite their groundbreaking applications across industries such as research, healthcare, and creative media, their rapid adoption raises critical concerns regarding sustainability. This survey paper comprehensively examines the environmental, economic, and computational challenges associated with LLMs, focusing on energy consumption, carbon emissions, and resource utilization in data centers. By synthesizing insights from existing literature, this work explores strategies such as resource-efficient training, sustainable deployment practices, and lifecycle assessments to mitigate the environmental impacts of LLMs. Key areas of emphasis include energy optimization, renewable energy integration, and balancing performance with sustainability. The findings aim to guide researchers, practitioners, and policymakers in developing actionable strategies for sustainable AI systems, fostering a responsible and environmentally conscious future for artificial intelligence.
Explingo: Explaining AI Predictions using Large Language Models
Zytek, Alexandra, Pido, Sara, Alnegheimish, Sarah, Berti-Equille, Laure, Veeramachaneni, Kalyan
Explanations of machine learning (ML) model predictions generated by Explainable AI (XAI) techniques such as SHAP are essential for people using ML outputs for decision-making. We explore the potential of Large Language Models (LLMs) to transform these explanations into human-readable, narrative formats that align with natural communication. We address two key research questions: (1) Can LLMs reliably transform traditional explanations into high-quality narratives? and (2) How can we effectively evaluate the quality of narrative explanations? To answer these questions, we introduce Explingo, which consists of two LLM-based subsystems, a Narrator and Grader. The Narrator takes in ML explanations and transforms them into natural-language descriptions. The Grader scores these narratives on a set of metrics including accuracy, completeness, fluency, and conciseness. Our experiments demonstrate that LLMs can generate high-quality narratives that achieve high scores across all metrics, particularly when guided by a small number of human-labeled and bootstrapped examples. We also identified areas that remain challenging, in particular for effectively scoring narratives in complex domains. The findings from this work have been integrated into an open-source tool that makes narrative explanations available for further applications.
Probabilistic Language-Image Pre-Training
Chun, Sanghyuk, Kim, Wonjae, Park, Song, Yun, Sangdoo
Vision-language models (VLMs) embed aligned image-text pairs into a joint space but often rely on deterministic embeddings, assuming a one-to-one correspondence between images and texts. This oversimplifies real-world relationships, which are inherently many-to-many, with multiple captions describing a single image and vice versa. We introduce Probabilistic Language-Image Pre-training (ProLIP), the first probabilistic VLM pre-trained on a billion-scale image-text dataset using only probabilistic objectives, achieving a strong zero-shot capability (e.g., 74.6% ImageNet zero-shot accuracy with ViT-B/16). ProLIP efficiently estimates uncertainty by an "uncertainty token" without extra parameters. We also introduce a novel inclusion loss that enforces distributional inclusion relationships between image-text pairs and between original and masked inputs. Experiments demonstrate that, by leveraging uncertainty estimates, ProLIP benefits downstream tasks and aligns with intuitive notions of uncertainty, e.g., shorter texts being more uncertain and more general inputs including specific ones. Utilizing text uncertainties, we further improve ImageNet accuracy from 74.6% to 75.8% (under a few-shot setting), supporting the practical advantages of our probabilistic approach. The code is available at https://github.com/naver-ai/prolip
ByteScience: Bridging Unstructured Scientific Literature and Structured Data with Auto Fine-tuned Large Language Model in Token Granularity
Xie, Tong, Zhang, Hanzhi, Wang, Shaozhou, Wan, Yuwei, Razzak, Imran, Kit, Chunyu, Zhang, Wenjie, Hoex, Bram
Natural Language Processing (NLP) is widely used to supply summarization ability from long context to structured information. However, extracting structured knowledge from scientific text by NLP models remains a challenge because of its domain-specific nature to complex data preprocessing and the granularity of multi-layered device-level information. To address this, we introduce ByteScience, a non-profit cloud-based auto fine-tuned Large Language Model (LLM) platform, which is designed to extract structured scientific data and synthesize new scientific knowledge from vast scientific corpora. The platform capitalizes on DARWIN, an open-source, fine-tuned LLM dedicated to natural science. The platform was built on Amazon Web Services (AWS) and provides an automated, user-friendly workflow for custom model development and data extraction. The platform achieves remarkable accuracy with only a small amount of well-annotated articles. This innovative tool streamlines the transition from the science literature to structured knowledge and data and benefits the advancements in natural informatics.
Can Large Language Models Serve as Effective Classifiers for Hierarchical Multi-Label Classification of Scientific Documents at Industrial Scale?
Tabatabaei, Seyed Amin, Fancher, Sarah, Parsons, Michael, Askari, Arian
We address the task of hierarchical multi-label classification (HMC) of scientific documents at an industrial scale, where hundreds of thousands of documents must be classified across thousands of dynamic labels. The rapid growth of scientific publications necessitates scalable and efficient methods for classification, further complicated by the evolving nature of taxonomies--where new categories are introduced, existing ones are merged, and outdated ones are deprecated. Traditional machine learning approaches, which require costly retraining with each taxonomy update, become impractical due to the high overhead of labelled data collection and model adaptation. Large Language Models (LLMs) have demonstrated great potential in complex tasks such as multi-label classification. However, applying them to large and dynamic taxonomies presents unique challenges as the vast number of labels can exceed LLMs' input limits. In this paper, we present novel methods that combine the strengths of LLMs with dense retrieval techniques to overcome these challenges. Our approach avoids retraining by leveraging zero-shot HMC for real-time label assignment. We evaluate the effectiveness of our methods on SSRN, a large repository of preprints spanning multiple disciplines, and demonstrate significant improvements in both classification accuracy and cost-efficiency. By developing a tailored evaluation framework for dynamic taxonomies and publicly releasing our code, this research provides critical insights into applying LLMs for document classification, where the number of classes corresponds to the number of nodes in a large taxonomy, at an industrial scale.
A text-to-tabular approach to generate synthetic patient data using LLMs
Tornqvist, Margaux, Zucker, Jean-Daniel, Fauvel, Tristan, Lambert, Nicolas, Berthelot, Mathilde, Movschin, Antoine
Access to large-scale high-quality healthcare databases is key to accelerate medical research and make insightful discoveries about diseases. However, access to such data is often limited by patient privacy concerns, data sharing restrictions and high costs. To overcome these limitations, synthetic patient data has emerged as an alternative. However, synthetic data generation (SDG) methods typically rely on machine learning (ML) models trained on original data, leading back to the data scarcity problem. We propose an approach to generate synthetic tabular patient data that does not require access to the original data, but only a description of the desired database. We leverage prior medical knowledge and in-context learning capabilities of large language models (LLMs) to generate realistic patient data, even in a low-resource setting. We quantitatively evaluate our approach against state-of-the-art SDG models, using fidelity, privacy, and utility metrics. Our results show that while LLMs may not match the performance of state-of-the-art models trained on the original data, they effectively generate realistic patient data with well-preserved clinical correlations. An ablation study highlights key elements of our prompt contributing to high-quality synthetic patient data generation. This approach, which is easy to use and does not require original data or advanced ML skills, is particularly valuable for quickly generating custom-designed patient data, supporting project implementation and providing educational resources.
Densing Law of LLMs
Xiao, Chaojun, Cai, Jie, Zhao, Weilin, Zeng, Guoyang, Lin, Biyuan, Zhou, Jie, Zheng, Zhi, Han, Xu, Liu, Zhiyuan, Sun, Maosong
Large Language Models (LLMs) have emerged as a milestone in artificial intelligence, and their performance can improve as the model size increases. However, this scaling brings great challenges to training and inference efficiency, particularly for deploying LLMs in resource-constrained environments, and the scaling trend is becoming increasingly unsustainable. This paper introduces the concept of ``\textit{capacity density}'' as a new metric to evaluate the quality of the LLMs across different scales and describes the trend of LLMs in terms of both effectiveness and efficiency. To calculate the capacity density of a given target LLM, we first introduce a set of reference models and develop a scaling law to predict the downstream performance of these reference models based on their parameter sizes. We then define the \textit{effective parameter size} of the target LLM as the parameter size required by a reference model to achieve equivalent performance, and formalize the capacity density as the ratio of the effective parameter size to the actual parameter size of the target LLM. Capacity density provides a unified framework for assessing both model effectiveness and efficiency. Our further analysis of recent open-source base LLMs reveals an empirical law (the densing law)that the capacity density of LLMs grows exponentially over time. More specifically, using some widely used benchmarks for evaluation, the capacity density of LLMs doubles approximately every three months. The law provides new perspectives to guide future LLM development, emphasizing the importance of improving capacity density to achieve optimal results with minimal computational overhead.
SLA Management in Reconfigurable Multi-Agent RAG: A Systems Approach to Question Answering
Iannelli, Michael, Kuchipudi, Sneha, Dvorak, Vera
Retrieval Augmented Generation (RAG) enables Large Language Models (LLMs) to generalize to new information by decoupling reasoning capabilities from static knowledge bases. Traditional RAG enhancements have explored vertical scaling -- assigning subtasks to specialized modules -- and horizontal scaling -- replicating tasks across multiple agents -- to improve performance. However, real-world applications impose diverse Service Level Agreements (SLAs) and Quality of Service (QoS) requirements, involving trade-offs among objectives such as reducing cost, ensuring answer quality, and adhering to specific operational constraints. In this work, we present a systems-oriented approach to multi-agent RAG tailored for real-world Question Answering (QA) applications. By integrating task-specific non-functional requirements -- such as answer quality, cost, and latency -- into the system, we enable dynamic reconfiguration to meet diverse SLAs. Our method maps these Service Level Objectives (SLOs) to system-level parameters, allowing the generation of optimal results within specified resource constraints. We conduct a case study in the QA domain, demonstrating how dynamic re-orchestration of a multi-agent RAG system can effectively manage the trade-off between answer quality and cost. By adjusting the system based on query intent and operational conditions, we systematically balance performance and resource utilization. This approach allows the system to meet SLOs for various query types, showcasing its practicality for real-world applications.
Random Tree Model of Meaningful Memory
Zhong, Weishun, Can, Tankut, Georgiou, Antonis, Shnayderman, Ilya, Katkov, Mikhail, Tsodyks, Misha
Traditional studies of memory for meaningful narratives focus on specific stories and their semantic structures but do not address common quantitative features of recall across different narratives. We introduce a statistical ensemble of random trees to represent narratives as hierarchies of key points, where each node is a compressed representation of its descendant leaves, which are the original narrative segments. Recall is modeled as constrained by working memory capacity from this hierarchical structure. Our analytical solution aligns with observations from large-scale narrative recall experiments. Specifically, our model explains that (1) average recall length increases sublinearly with narrative length, and (2) individuals summarize increasingly longer narrative segments in each recall sentence. Additionally, the theory predicts that for sufficiently long narratives, a universal, scale-invariant limit emerges, where the fraction of a narrative summarized by a single recall sentence follows a distribution independent of narrative length.