Mental health remains a critical global challenge, with increasing demand for accessible, effective interventions. Large language models (LLMs) offer promising solutions in psychotherapy by enhancing the assessment, diagnosis, and treatment of mental health conditions through dynamic, context-aware interactions. This survey provides a comprehensive overview of the current landscape of LLM applications in psychotherapy, highlighting the roles of LLMs in symptom detection, severity estimation, cognitive assessment, and therapeutic interventions. We present a novel conceptual taxonomy to organize the psychotherapy process into three core components: assessment, diagnosis, and treatment, and examine the challenges and advancements in each area. The survey also addresses key research gaps, including linguistic biases, limited disorder coverage, and underrepresented therapeutic models. Finally, we discuss future directions to integrate LLMs into a holistic, end-to-end psychotherapy framework, addressing the evolving nature of mental health conditions and fostering more inclusive, personalized care.

We present the Mixture-of-Tunable-Experts (MoTE), a method that extends the Mixture-of-Experts architecture of Large Language Models (LLMs). Without additional training, MoTE enables meaningful and focused behavior changes in LLMs on-the-fly during inference time. By analyzing the digital LLM brain of DeepSeek-R1 using a technique we dub 'functional Token Resonance Imaging' (fTRI) - inspired by fMRI and using prompts designed to elicit specific behavior (e.g., 'What happened {time}{place}?') - we empirically identify distinctive experts associated with behaviors like refusal responses. Using MoTE we are able to intervene and control such specific behavior. We switched off the top 10 most refusal-relevant experts (0.07% of R1's 14,848 routed experts), achieving a 52% refusal reduction on sensitive reference prompts without performance degradation on MT-Bench. Random expert deactivation resulted in smaller behavioral shifts with increased noise, whereas forced expert activation led to significantly higher refusal rates. Our approach shares similarities with sparse autoencoders (SAEs) in terms of explainability and steerability. Unlike SAEs, MoTE does not require large training efforts, as within MoEs with a vast number of experts, specialization already emerged naturally during pretraining. Our findings suggest that significant functional mechanisms in Mixture-of-Experts architectures can at least partially be localized in a small number of specific experts, rather than being distributed throughout the model's weights. Expert subgroups can be tuned to trigger significant behavior variations, providing insights into the inner workings of LLMs.

Large Language Models (LLMs) excel across a variety of language tasks yet are constrained by limited input lengths and high computational costs. Existing approaches\textemdash such as relative positional encodings (e.g., RoPE, ALiBi) and sliding window mechanisms\textemdash partially alleviate these issues but often require additional training or suffer from performance degradation with longer inputs. In this paper, we introduce \textbf{\textit{CacheFocus}}, a method that enhances length normalization and reduces inference latency without any further training. Our approach leverages query-independent, offline caching to efficiently reuse a Context KV Cache Store. We address the amplification of abnormal token distributions problem by re-positioning cached keys and introducing Layer-Adaptive Cache Pruning to discard low-relevance caches during pre-filling. Additionally, our Adaptive Positional Allocation Strategy dynamically reassigns cache positions to maximize the use of the available positional encoding range. Experiments on the Natural Questions and TriviaQA datasets demonstrate that CacheFocus outperforms alternative methods even when inputs exceed the $4$K limit of the \texttt{LLaMA-2} model, emphasizing its practical effectiveness for long-context LLMs. Moreover, even with large maximum input length of \texttt{Qwen2}, the performance of CacheFocus shows that it maintains consistent performance even as the number of documents increases, effectively managing long-text generation without degradation.

Knowledge Distillation (KD) has emerged as a prominent technique for model compression. However, conventional KD approaches primarily focus on homogeneous architectures with identical tokenizers, constraining their applicability in cross-architecture scenarios. As for the cross-tokenizer KD, the differences in the tokenizers give rise to two fundamental challenges: (1) sequence misalignment caused by divergent tokenization strategies, and (2) mismatched vocabulary size and composition. While existing probability-matching methods attempt to address these issues, their efficacy remains limited due to suboptimal alignment in both the sequence and vocabulary aspects. To overcome these limitations, we propose Contextual Dynamic Mapping (CDM), a novel cross-tokenizer distillation framework that employs contextual information to enhance sequence alignment precision and dynamically improves vocabulary mapping. We evaluated the effectiveness of our approach across five advanced and widely-used model families (i.e, LLama3, Phi3, Gemma2, OPT and Qwen2), which were configured into three distinct teacher-student pairs. Our method shows significant advantages over existing cross-tokenizer distillation baselines across diverse benchmarks, including instruction-following, code generation and math. Notably, our analysis reveals that combining conventional same-tokenizer distillation and cross-tokenizer distillation through CDM yields further performance improvements. The code is available at https://github.com/pppa2019/ContexualDynamicMapping

As large language models advance toward superhuman performance, ensuring their alignment with human values and abilities grows increasingly complex. Weak-to-strong generalization offers a promising approach by leveraging predictions from weaker models to guide stronger systems, but its effectiveness could be constrained by the inherent noise and inaccuracies in these weak predictions. To address this, we propose a theoretically grounded approach that replaces forward KL divergence-whose mass-covering behavior risks overfitting to imperfect weak signals-with reverse KL divergence. Reverse KL divergence's zero-forcing effect prioritizes high-confidence predictions, effectively mitigating the influence of unreliable weak supervision. Theoretically, we extend existing bounds and derive tighter lower bounds for both forward and reverse KL divergence, establishing that reverse KL achieves at least comparable guarantees to forward KL. Notably, when a sufficiently pre-trained strong model is fine-tuned on the last layer, reverse KL uniquely guarantees that it outperforms its weak supervisor by the magnitude of their disagreement-a guarantee that forward KL cannot provide. Empirically, we demonstrate that reverse KL and reverse cross-entropy enable strong models to consistently outperform those trained with forward KL and standard cross-entropy across most settings, highlighting the practical advantages of these reverse losses.

Large language models (LLMs) have significantly advanced the field of natural language generation. However, they frequently generate unverified outputs, which compromises their reliability in critical applications. In this study, we propose an innovative framework that combines structured biomedical knowledge with LLMs through a retrieval-augmented generation technique. Our system develops a thorough knowledge graph by identifying and refining causal relationships and named entities from medical abstracts related to age-related macular degeneration (AMD). Using a vector-based retrieval process and a locally deployed language model, our framework produces responses that are both contextually relevant and verifiable, with direct references to clinical evidence. Experimental results show that this method notably decreases hallucinations, enhances factual precision, and improves the clarity of generated responses, providing a robust solution for advanced biomedical chatbot applications.

Temporal relation extraction (TRE) is a fundamental task in natural language processing (NLP) that involves identifying the temporal relationships between events in a document. Despite the advances in large language models (LLMs), their application to TRE remains limited. Most existing approaches rely on pairwise classification, in which event pairs are considered individually, leading to computational inefficiency and a lack of global consistency in the resulting temporal graph. In this work, we propose a novel zero-shot method for TRE that generates a document's complete temporal graph at once, then applies transitive constraints optimization to refine predictions and enforce temporal consistency across relations. Additionally, we introduce OmniTemp, a new dataset with complete annotations for all pairs of targeted events within a document. Through experiments and analyses, we demonstrate that our method significantly outperforms existing zero-shot approaches while achieving competitive performance with supervised models.

RAG systems rely on rerankers to identify relevant documents. However, fine-tuning these models remains challenging due to the scarcity of annotated query-document pairs. Existing distillation-based approaches suffer from training-inference misalignment and fail to capture interdependencies among candidate documents. To overcome these limitations, we reframe the reranking process as an attention-mask problem and propose Gumbel Reranking, an end-to-end training framework for rerankers aimed at minimizing the training-inference gap. In our approach, reranker optimization is reformulated as learning a stochastic, document-wise Top-$k$ attention mask using the Gumbel Trick and Relaxed Top-$k$ Sampling. This formulation enables end-to-end optimization by minimizing the overall language loss. Experiments across various settings consistently demonstrate performance gains, including a 10.4\% improvement in recall on HotpotQA for distinguishing indirectly relevant documents.

Since the emergence of the Large Language Model (LLM), LLM has been widely used in fields such as writing, translating, and searching. However, there is still great potential for LLM-based methods in handling complex tasks such as decision-making in the StarCraft II environment. To address problems such as lack of relevant knowledge and poor control over subtasks of varying importance, we propose a Hierarchical Expert Prompt (HEP) for LLM. Our method improves the understanding of game situations through expert-level tactical knowledge, improving the processing quality of tasks of varying importance through a hierarchical framework. Our approach defeated the highest level (Elite) standard built-in agent in TextStarCraft II for the first time and consistently outperformed the baseline method in other difficulties. Our experiments suggest that the proposed method is a practical solution for tackling complex decision-making challenges. The replay video can be viewed on https://www.bilibili.com/video/BV1uz42187EF and https://youtu.be/dO3PshWLV5M, and our codes have been open-sourced on https://github.com/luchang1113/HEP-LLM-play-StarCraftII.

Large Language Model (LLM)-based Multi-agent Systems (MAS) have demonstrated remarkable capabilities in various complex tasks, ranging from collaborative problem-solving to autonomous decision-making. However, as these systems become increasingly integrated into critical applications, their vulnerability to adversarial attacks, misinformation propagation, and unintended behaviors have raised significant concerns. To address this challenge, we introduce G-Safeguard, a topology-guided security lens and treatment for robust LLM-MAS, which leverages graph neural networks to detect anomalies on the multi-agent utterance graph and employ topological intervention for attack remediation. Extensive experiments demonstrate that G-Safeguard: (I) exhibits significant effectiveness under various attack strategies, recovering over 40% of the performance for prompt injection; (II) is highly adaptable to diverse LLM backbones and large-scale MAS; (III) can seamlessly combine with mainstream MAS with security guarantees. The code is available at https://github.com/wslong20/G-safeguard.