Automatic medical coding has the potential to ease documentation and billing processes. For this task, transparency plays an important role for medical coders and regulatory bodies, which can be achieved using explainability methods. However, the evaluation of these approaches has been mostly limited to short text and binary settings due to a scarcity of annotated data. Recent efforts by Cheng et al. (2023) have introduced the MDACE dataset, which provides a valuable resource containing code evidence in clinical records. In this work, we conduct an in-depth analysis of the MDACE dataset and perform plausibility evaluation of current explainable medical coding systems from an applied perspective. With this, we contribute to a deeper understanding of automatic medical coding and evidence extraction. Our findings reveal that ground truth evidence aligns with code descriptions to a certain degree. An investigation into state-of-the-art approaches shows a high overlap with ground truth evidence. We propose match measures and highlight success and failure cases. Based on our findings, we provide recommendations for developing and evaluating explainable medical coding systems.

Large Language Models (LLMs) have gained significant attention due to their versatility across a wide array of applications. Fine-tuning LLMs with parameter-efficient adapters, such as Low-Rank Adaptation (LoRA), enables these models to efficiently adapt to downstream tasks without extensive retraining. Deploying fine-tuned LLMs on multi-tenant edge devices offers substantial benefits, such as reduced latency, enhanced privacy, and personalized responses. However, serving LLMs efficiently on resource-constrained edge devices presents critical challenges, including the complexity of adapter selection for different tasks and memory overhead from frequent adapter swapping. Moreover, given the multiple requests in multi-tenant settings, processing requests sequentially results in underutilization of computational resources and increased latency. This paper introduces EdgeLoRA, an efficient system for serving LLMs on edge devices in multi-tenant environments. EdgeLoRA incorporates three key innovations: (1) an adaptive adapter selection mechanism to streamline the adapter configuration process; (2) heterogeneous memory management, leveraging intelligent adapter caching and pooling to mitigate memory operation overhead; and (3) batch LoRA inference, enabling efficient batch processing to significantly reduce computational latency. Comprehensive evaluations using the Llama3.1-8B model demonstrate that EdgeLoRA significantly outperforms the status quo (i.e., llama.cpp) in terms of both latency and throughput. The results demonstrate that EdgeLoRA can achieve up to a 4 times boost in throughput. Even more impressively, it can serve several orders of magnitude more adapters simultaneously. These results highlight EdgeLoRA's potential to transform edge deployment of LLMs in multi-tenant scenarios, offering a scalable and efficient solution for resource-constrained environments.

In-context learning (ICL) has demonstrated remarkable success in large language models (LLMs) due to its adaptability and parameter-free nature. However, it also introduces a critical vulnerability to backdoor attacks, where adversaries can manipulate LLM behaviors by simply poisoning a few ICL demonstrations. In this paper, we propose, for the first time, the dual-learning hypothesis, which posits that LLMs simultaneously learn both the task-relevant latent concepts and backdoor latent concepts within poisoned demonstrations, jointly influencing the probability of model outputs. Through theoretical analysis, we derive an upper bound for ICL backdoor effects, revealing that the vulnerability is dominated by the concept preference ratio between the task and the backdoor. Motivated by these findings, we propose ICLShield, a defense mechanism that dynamically adjusts the concept preference ratio. Our method encourages LLMs to select clean demonstrations during the ICL phase by leveraging confidence and similarity scores, effectively mitigating susceptibility to backdoor attacks. Extensive experiments across multiple LLMs and tasks demonstrate that our method achieves state-of-the-art defense effectiveness, significantly outperforming existing approaches (+26.02% on average). Furthermore, our method exhibits exceptional adaptability and defensive performance even for closed-source models (e.g., GPT-4).

Fine-tuning pre-trained large language models (LLMs) in a distributed manner poses significant challenges on resource-constrained edge networks. To address this challenge, we propose SflLLM, a novel framework that integrates split federated learning with parameter-efficient fine-tuning techniques. By leveraging model splitting and low-rank adaptation (LoRA), SflLLM reduces the computational burden on edge devices. Furthermore, the introduction of a federated server facilitates parallel training and enhances data privacy. To accommodate heterogeneous communication conditions and diverse computational capabilities of edge devices, as well as the impact of LoRA rank selection on model convergence and training cost, we formulate a joint optimization problem of both communication and computation resource. The formulated problem jointly optimizes subchannel allocation, power control, model splitting point selection, and LoRA rank configuration, aimed at minimizing total training delay. An iterative optimization algorithm is proposed to solve this problem efficiently. Specifically, a greedy heuristic is employed for subchannel allocation, the power control subproblem is reformulated as a convex optimization problem using auxiliary variables, and an exhaustive search is adopted for optimal split position and rank selection. Simulation results demonstrate that the proposed SflLLM framework achieves comparable model accuracy while significantly reducing client-side computational requirements. Furthermore, the proposed resource allocation scheme and adaptive LoRA rank selection strategy notably reduce the training latency compared to conventional approaches.

Foundation models are at the forefront of AI research, appealing for their ability to learn from vast datasets and cater to diverse tasks. Yet, their significant computational demands raise issues of environmental impact and the risk of centralized control in their development. We put forward a vision towards decentralized and sustainable foundation model training that leverages the collective compute of sparingly used connected edge AI devices. We present the rationale behind our vision, particularly in support of its sustainability benefit. We further outline a set of challenges that need to be addressed to turn this vision into reality.

The Alps Research Infrastructure leverages GH200 technology at scale, featuring 10,752 GPUs. Accessing Alps provides a significant computational advantage for researchers in Artificial Intelligence (AI) and Machine Learning (ML). While Alps serves a broad range of scientific communities, traditional HPC services alone are not sufficient to meet the dynamic needs of the ML community. This paper presents an initial investigation into extending HPC service capabilities to better support ML workloads. We identify key challenges and gaps we have observed since the early-access phase (2023) of Alps by the Swiss AI community and propose several technological enhancements. These include a user environment designed to facilitate the adoption of HPC for ML workloads, balancing performance with flexibility; a utility for rapid performance screening of ML applications during development; observability capabilities and data products for inspecting ongoing large-scale ML workloads; a utility to simplify the vetting of allocated nodes for compute readiness; a service plane infrastructure to deploy various types of workloads, including support and inference services; and a storage infrastructure tailored to the specific needs of ML workloads. These enhancements aim to facilitate the execution of ML workloads on HPC systems, increase system usability and resilience, and better align with the needs of the ML community. We also discuss our current approach to security aspects. This paper concludes by placing these proposals in the broader context of changes in the communities served by HPC infrastructure like ours.

There is justifiable interest in leveraging conversational AI (CAI) for health across the majority world, but to be effective, CAI must respond appropriately within cultur ally and linguistically diverse context s . Therefore, we need ways to address the fact that current LLMs exclude many lived experience s globally . Various advances are underway which focus on top - down approaches and increas ing training data . In this paper, we aim to complement these with a bottom - up locally - grounded approach based on qualitative data collected during participatory workshops in Latin America. Our goal is to construct a rich and human - centred understanding o f: a) potential areas of cultural misalignment in digital health; b) regional perspectives on chatbots for health and c) strategies for creating culturally - appropriate CAI; with a focus on the understudied Latin American context . Our findings show that academic boundaries on notions of cultur e lose meaning at the ground level and technologies will need to engage with a broad er framework; one that encapsulates the way economics, politics, geogr aphy and local logistics are entangled in cultural experience. To this end, we introduce a framework for ' Pluriversal Conversational AI for H ealth ' which allows for the possibility that more relationality and tolerance, rather than just more data, may be called for .

Reinforcement Learning from Human Feedback (RLHF) has emerged as a powerful technique for aligning large language models (LLMs) with human preferences. However, effectively aligning LLMs with diverse human preferences remains a significant challenge, particularly when they are conflict. To address this issue, we frame human value alignment as a multi-objective optimization problem, aiming to maximize a set of potentially conflicting objectives. We introduce Gradient-Adaptive Policy Optimization (GAPO), a novel fine-tuning paradigm that employs multiple-gradient descent to align LLMs with diverse preference distributions. GAPO adaptively rescales the gradients for each objective to determine an update direction that optimally balances the trade-offs between objectives. Additionally, we introduce P-GAPO, which incorporates user preferences across different objectives and achieves Pareto solutions that better align with the user's specific needs. Our theoretical analysis demonstrates that GAPO converges towards a Pareto optimal solution for multiple objectives. Empirical results on Mistral-7B show that GAPO outperforms current state-of-the-art methods, achieving superior performance in both helpfulness and harmlessness.

Task-oriented dialogue (ToD) systems are designed to help users achieve specific goals through natural language interaction. While recent advances in large language models (LLMs) have significantly improved linguistic fluency and contextual understanding, building effective and emotionally intelligent ToD systems remains a complex challenge. Effective ToD systems must optimise for task success, emotional understanding and responsiveness, and precise information conveyance, all within inherently noisy and ambiguous conversational environments. In this work, we investigate architectural, representational, optimisational as well as emotional considerations of ToD systems. We set up systems covering these design considerations with a challenging evaluation environment composed of a natural-language user simulator coupled with an imperfect natural language understanding module. We propose \textbf{LUSTER}, an \textbf{L}LM-based \textbf{U}nified \textbf{S}ystem for \textbf{T}ask-oriented dialogue with \textbf{E}nd-to-end \textbf{R}einforcement learning with both short-term (user sentiment) and long-term (task success) rewards. Our findings demonstrate that combining LLM capability with structured reward modelling leads to more resilient and emotionally responsive ToD systems, offering a practical path forward for next-generation conversational agents.

Low-Rank Adapters (LoRAs) have transformed the fine-tuning of Large Language Models (LLMs) by enabling parameter-efficient updates. However, their widespread adoption remains limited by the reliance on GPU-based training. In this work, we propose a theoretically grounded approach to LoRA fine-tuning designed specifically for users with limited computational resources, particularly those restricted to standard laptop CPUs. Our method learns a meta-operator that maps any input dataset, represented as a probability distribution, to a set of LoRA weights by leveraging a large bank of pre-trained adapters for the Mistral-7B-Instruct-v0.2 model. Instead of performing new gradient-based updates, our pipeline constructs adapters via lightweight combinations of existing LoRAs directly on CPU. While the resulting adapters do not match the performance of GPU-trained counterparts, they consistently outperform the base Mistral model on downstream tasks, offering a practical and accessible alternative to traditional GPU-based fine-tuning.