Large Language Model
ShizhenGPT: Towards Multimodal LLMs for Traditional Chinese Medicine
Chen, Junying, Cai, Zhenyang, Liu, Zhiheng, Yang, Yunjin, Wang, Rongsheng, Xiao, Qingying, Feng, Xiangyi, Su, Zhan, Guo, Jing, Wan, Xiang, Yu, Guangjun, Li, Haizhou, Wang, Benyou
Despite the success of large language models (LLMs) in various domains, their potential in Traditional Chinese Medicine (TCM) remains largely underexplored due to two critical barriers: (1) the scarcity of high-quality TCM data and (2) the inherently multimodal nature of TCM diagnostics, which involve looking, listening, smelling, and pulse-taking. These sensory-rich modalities are beyond the scope of conventional LLMs. To address these challenges, we present ShizhenGPT, the first multimodal LLM tailored for TCM. To overcome data scarcity, we curate the largest TCM dataset to date, comprising 100GB+ of text and 200GB+ of multimodal data, including 1.2M images, 200 hours of audio, and physiological signals. ShizhenGPT is pretrained and instruction-tuned to achieve deep TCM knowledge and multimodal reasoning. For evaluation, we collect recent national TCM qualification exams and build a visual benchmark for Medicinal Recognition and Visual Diagnosis. Experiments demonstrate that ShizhenGPT outperforms comparable-scale LLMs and competes with larger proprietary models. Moreover, it leads in TCM visual understanding among existing multimodal LLMs and demonstrates unified perception across modalities like sound, pulse, smell, and vision, paving the way toward holistic multimodal perception and diagnosis in TCM. Datasets, models, and code are publicly available. We hope this work will inspire further exploration in this field.
MCP-Universe: Benchmarking Large Language Models with Real-World Model Context Protocol Servers
Luo, Ziyang, Shen, Zhiqi, Yang, Wenzhuo, Zhao, Zirui, Jwalapuram, Prathyusha, Saha, Amrita, Sahoo, Doyen, Savarese, Silvio, Xiong, Caiming, Li, Junnan
The Model Context Protocol has emerged as a transformative standard for connecting large language models to external data sources and tools, rapidly gaining adoption across major AI providers and development platforms. However, existing benchmarks are overly simplistic and fail to capture real application challenges such as long-horizon reasoning and large, unfamiliar tool spaces. To address this critical gap, we introduce MCP-Universe, the first comprehensive benchmark specifically designed to evaluate LLMs in realistic and hard tasks through interaction with real-world MCP servers. Our benchmark encompasses 6 core domains spanning 11 different MCP servers: Location Navigation, Repository Management, Financial Analysis, 3D Design, Browser Automation, and Web Searching. To ensure rigorous evaluation, we implement execution-based evaluators, including format evaluators for agent format compliance, static evaluators for time-invariant content matching, and dynamic evaluators that automatically retrieve real-time ground truth for temporally sensitive tasks. Through extensive evaluation of leading LLMs, we find that even SOTA models such as GPT-5 (43.72%), Grok-4 (33.33%) and Claude-4.0-Sonnet (29.44%) exhibit significant performance limitations. In addition, our benchmark poses a significant long-context challenge for LLM agents, as the number of input tokens increases rapidly with the number of interaction steps. Moreover, it introduces an unknown-tools challenge, as LLM agents often lack familiarity with the precise usage of the MCP servers. Notably, enterprise-level agents like Cursor cannot achieve better performance than standard ReAct frameworks. Beyond evaluation, we open-source our extensible evaluation framework with UI support, enabling researchers and practitioners to seamlessly integrate new agents and MCP servers while fostering innovation in the rapidly evolving MCP ecosystem.
Virtual Community: An Open World for Humans, Robots, and Society
Zhou, Qinhong, Zhang, Hongxin, Lin, Xiangye, Zhang, Zheyuan, Chen, Yutian, Liu, Wenjun, Zhang, Zunzhe, Chen, Sunli, Fang, Lixing, Lyu, Qiushi, Sun, Xinyu, Yang, Jincheng, Wang, Zeyuan, Dang, Bao Chi, Chen, Zhehuan, Ladia, Daksha, Liu, Jiageng, Gan, Chuang
The rapid progress in AI and Robotics may lead to a profound societal transformation, as humans and robots begin to coexist within shared communities, introducing both opportunities and challenges. To explore this future, we present Virtual Community-an open-world platform for humans, robots, and society-built on a universal physics engine and grounded in real-world 3D scenes. With Virtual Community, we aim to study embodied social intelligence at scale: 1) How robots can intelligently cooperate or compete; 2) How humans develop social relations and build community; 3) More importantly, how intelligent robots and humans can co-exist in an open world. To support these, Virtual Community features: 1) An open-source multi-agent physics simulator that supports robots, humans, and their interactions within a society; 2) A large-scale, real-world aligned community generation pipeline, including vast outdoor space, diverse indoor scenes, and a community of grounded agents with rich characters and appearances. Leveraging Virtual Community, we propose two novel challenges. The Community Planning Challenge evaluates multi-agent reasoning and planning ability in open-world settings, such as cooperating to help agents with daily activities and efficiently connecting other agents. The Community Robot Challenge requires multiple heterogeneous robots to collaborate in solving complex open-world tasks. We evaluate various baselines on these tasks and demonstrate the challenges in both high-level open-world task planning and low-level cooperation controls. We hope that Virtual Community will unlock further study of human-robot coexistence within open-world environments.
The Prompting Brain: Neurocognitive Markers of Expertise in Guiding Large Language Models
Al-Khalifa, Hend, Almansour, Raneem, Alhuasini, Layan Abdulrahman, Alsaleh, Alanood, Temsah, Mohamad-Hani, Mohamad-Hani_Temsah, null, Alruwaili, Ashwag Rafea S
Prompt engineering has rapidly emerged as a critical skill for effective interaction with large language models (LLMs). However, the cognitive and neural underpinnings of this expertise remain largely unexplored. This paper presents findings from a cross-sectional pilot fMRI study investigating differences in brain functional connectivity and network activity between experts and intermediate prompt engineers. Our results reveal distinct neural signatures associated with higher prompt engineering literacy, including increased functional connectivity in brain regions such as the left middle temporal gyrus and the left frontal pole, as well as altered power-frequency dynamics in key cognitive networks. These findings offer initial insights into the neurobiological basis of prompt engineering proficiency. We discuss the implications of these neurocognitive markers in Natural Language Processing (NLP). Understanding the neural basis of human expertise in interacting with LLMs can inform the design of more intuitive human-AI interfaces, contribute to cognitive models of LLM interaction, and potentially guide the development of AI systems that better align with human cognitive workflows. This interdisciplinary approach aims to bridge the gap between human cognition and machine intelligence, fostering a deeper understanding of how humans learn and adapt to complex AI systems.
Universal and Transferable Adversarial Attack on Large Language Models Using Exponentiated Gradient Descent
Biswas, Sajib, Nishino, Mao, Chacko, Samuel Jacob, Liu, Xiuwen
As large language models (LLMs) are increasingly deployed in critical applications, ensuring their robustness and safety alignment remains a major challenge. Despite the overall success of alignment techniques such as reinforcement learning from human feedback (RLHF) on typical prompts, LLMs remain vulnerable to jailbreak attacks enabled by crafted adversarial triggers appended to user prompts. Most existing jailbreak methods either rely on inefficient searches over discrete token spaces or direct optimization of continuous embeddings. While continuous embeddings can be given directly to selected open-source models as input, doing so is not feasible for proprietary models. On the other hand, projecting these embeddings back into valid discrete tokens introduces additional complexity and often reduces attack effectiveness. We propose an intrinsic optimization method which directly optimizes relaxed one-hot encodings of the adversarial suffix tokens using exponentiated gradient descent coupled with Bregman projection, ensuring that the optimized one-hot encoding of each token always remains within the probability simplex. We provide theoretical proof of convergence for our proposed method and implement an efficient algorithm that effectively jailbreaks several widely used LLMs. Our method achieves higher success rates and faster convergence compared to three state-of-the-art baselines, evaluated on five open-source LLMs and four adversarial behavior datasets curated for evaluating jailbreak methods. In addition to individual prompt attacks, we also generate universal adversarial suffixes effective across multiple prompts and demonstrate transferability of optimized suffixes to different LLMs.
Evaluating Retrieval-Augmented Generation vs. Long-Context Input for Clinical Reasoning over EHRs
Myers, Skatje, Dligach, Dmitriy, Miller, Timothy A., Barr, Samantha, Gao, Yanjun, Churpek, Matthew, Mayampurath, Anoop, Afshar, Majid
Electronic health records (EHRs) are long, noisy, and often redundant, posing a major challenge for the clinicians who must navigate them. Large language models (LLMs) offer a promising solution for extracting and reasoning over this unstructured text, but the length of clinical notes often exceeds even state-of-the-art models' extended context windows. Retrieval-augmented generation (RAG) offers an alternative by retrieving task-relevant passages from across the entire EHR, potentially reducing the amount of required input tokens. In this work, we propose three clinical tasks designed to be replicable across health systems with minimal effort: 1) extracting imaging procedures, 2) generating timelines of antibiotic use, and 3) identifying key diagnoses. Using EHRs from actual hospitalized patients, we test three state-of-the-art LLMs with varying amounts of provided context, using either targeted text retrieval or the most recent clinical notes. We find that RAG closely matches or exceeds the performance of using recent notes, and approaches the performance of using the models' full context while requiring drastically fewer input tokens. Our results suggest that RAG remains a competitive and efficient approach even as newer models become capable of handling increasingly longer amounts of text.
Privileged Self-Access Matters for Introspection in AI
Song, Siyuan, Lederman, Harvey, Hu, Jennifer, Mahowald, Kyle
Whether AI models can introspect is an increasingly important practical question. But there is no consensus on how introspection is to be defined. Beginning from a recently proposed ''lightweight'' definition, we argue instead for a thicker one. According to our proposal, introspection in AI is any process which yields information about internal states through a process more reliable than one with equal or lower computational cost available to a third party. Using experiments where LLMs reason about their internal temperature parameters, we show they can appear to have lightweight introspection while failing to meaningfully introspect per our proposed definition.
HERAKLES: Hierarchical Skill Compilation for Open-ended LLM Agents
Carta, Thomas, Romac, Clรฉment, Gaven, Loris, Oudeyer, Pierre-Yves, Sigaud, Olivier, Lamprier, Sylvain
Open-ended AI agents need to be able to learn efficiently goals of increasing complexity, abstraction and heterogeneity over their lifetime. Beyond sampling efficiently their own goals, autotelic agents specifically need to be able to keep the growing complexity of goals under control, limiting the associated growth in sample and computational complexity. To adress this challenge, recent approaches have leveraged hierarchical reinforcement learning (HRL) and language, capitalizing on its compositional and combinatorial generalization capabilities to acquire temporally extended reusable behaviours. Existing approaches use expert defined spaces of subgoals over which they instantiate a hierarchy, and often assume pre-trained associated low-level policies. Such designs are inadequate in open-ended scenarios, where goal spaces naturally diversify across a broad spectrum of difficulties. We introduce HERAKLES, a framework that enables a two-level hierarchical autotelic agent to continuously compile mastered goals into the low-level policy, executed by a small, fast neural network, dynamically expanding the set of subgoals available to the high-level policy. We train a Large Language Model (LLM) to serve as the high-level controller, exploiting its strengths in goal decomposition and generalization to operate effectively over this evolving subgoal space. We evaluate HERAKLES in the open-ended Crafter environment and show that it scales effectively with goal complexity, improves sample efficiency through skill compilation, and enables the agent to adapt robustly to novel challenges over time.
Evaluating Multilingual and Code-Switched Alignment in LLMs via Synthetic Natural Language Inference
Abdaljalil, Samir, Serpedin, Erchin, Qaraqe, Khalid, Kurban, Hasan
Large language models (LLMs) are increasingly applied in multilingual contexts, yet their capacity for consistent, logically grounded alignment across languages remains underexplored. We present a controlled evaluation framework for multilingual natural language inference (NLI) that generates synthetic, logic-based premise-hypothesis pairs and translates them into a typologically diverse set of languages. This design enables precise control over semantic relations and allows testing in both monolingual and mixed-language (code-switched) conditions. Surprisingly, code-switching does not degrade, and can even improve, performance, suggesting that translation-induced lexical variation may serve as a regularization signal. We validate semantic preservation through embedding-based similarity analyses and cross-lingual alignment visualizations, confirming the fidelity of translated pairs. Our findings expose both the potential and the brittleness of current LLM cross-lingual reasoning, and identify code-switching as a promising lever for improving multilingual robustness. Code available at: https://github.com/KurbanIntelligenceLab/nli-stress-testing
The Digital Sous Chef -- A Comparative Study on Fine-Tuning Language Models for Recipe Generation
Pundhir, Shubham, Bagler, Ganesh
We established a rigorous benchmark for text-based recipe generation, a fundamental task in natural language generation. We present a comprehensive comparative study contrasting a fine-tuned GPT -2 large (774M) model against the GPT -2 small (124M) model and traditional LSTM/RNN baselines on the 5-cuisine corpus from RecipeDB. Our key contribution is a targeted tokenization strategy that augments the vocabulary with 23 common fraction tokens and custom structural markers. This approach addresses a critical limitation of generic tokenizers by preserving essential recipe structures and precise numerical quantities, thereby enhancing domain specificity. Performance is evaluated using a comprehensive suite of seven automatic metrics spanning fluency (BLEU-4, METEOR), coherence (ROUGE-L), semantic relevance (BERTScore), and diversity. Our experiments show that the large transformer-based approach yields a > 20% relative improvement in BERTScore (F1) (0.92 vs 0.72) over the best recurrent baseline, while reducing perplexity by 69.8%. We conclude with a discussion of remaining challenges, particularly regarding factual accuracy, and outline how this foundational study paves the way for integrating real-world constraints and multi-modal inputs in advanced recipe generation research.