Accurate recognition of biomedical named entities is critical for medical information extraction and knowledge discovery. However, existing methods often struggle with nested entities, entity boundary ambiguity, and cross-lingual generalization. In this paper, we propose a unified Biomedical Named Entity Recognition (BioNER) framework based on Large Language Models (LLMs). We first reformulate BioNER as a text generation task and design a symbolic tagging strategy to jointly handle both flat and nested entities with explicit boundary annotation. To enhance multilingual and multi-task generalization, we perform bilingual joint fine-tuning across multiple Chinese and English datasets. Additionally, we introduce a contrastive learning-based entity selector that filters incorrect or spurious predictions by leveraging boundary-sensitive positive and negative samples. Experimental results on four benchmark datasets and two unseen corpora show that our method achieves state-of-the-art performance and robust zero-shot generalization across languages. The source codes are freely available at https://github.com/dreamer-tx/LLMNER.

We present HES-SQL, a novel hybrid training framework that advances Text-to-SQL generation through the integration of thinking-mode-fused supervised fine-tuning (SFT) with Group Relative Policy Optimization (GRPO). Our approach introduces three key innovations: (1) a skeleton-completeness scoring mechanism that enhances preference alignment between generated queries and optimal SQL structures; (2) a query-latency-aware reward system that incentivizes the generation of computationally efficient SQL queries; (3) a self-distillation process for thinking-mode completion that prevents degradation of the model's reasoning capabilities. This framework enables hybrid thinking models to switch between reasoning and non-reasoning modes while improving SQL query accuracy and execution efficiency. Experimental evaluation, conducted on MySQL 8.0 and SQLite 3.42 under controlled single-user conditions, demonstrates that HES-SQL achieves competitive performance with execution accuracies of 79.14\% and 54.9\% on the BIRD and KaggleDBQA benchmarks, respectively. Query latency is measured as the end-to-end execution time of generated queries on the DBMS, averaged over multiple runs to mitigate variance. Efficiency gains range from 11\% to 20\% relative to supervised baselines. Our results establish a new paradigm for Text-to-SQL systems that effectively balances semantic accuracy with computational efficiency through execution-informed reinforcement learning (RL). The proposed methodology has significant implications for developing robust natural language interfaces to databases and can be extended to broader structured generation tasks requiring both correctness and efficiency optimization.

Reinforcement Learning has demonstrated substantial improvements in the reasoning abilities of Large Language Models (LLMs), exhibiting significant applicability across various domains. Recent research has identified that tokens within LLMs play distinct roles during reasoning tasks, categorizing them into high-entropy reasoning tokens and low-entropy knowledge tokens. Prior approaches have typically focused on restricting updates to indirectly encourage exploration, yet they do not explicitly facilitate exploratory behavior during the token generation stage itself. In this work, we introduce a complementary approach that explicitly promotes exploration during sampling by applying distinct temperature settings for different token types. Specifically, our method employs higher temperatures for reasoning tokens to actively encourage exploration, while retaining lower temperatures for knowledge tokens to maintain factual correctness. Furthermore, we systematically investigate various multi-temperature scheduling strategies and their impacts within reinforcement learning contexts. Empirical evaluations on several reasoning benchmarks demonstrate that our approach significantly enhances the reasoning performance of LLMs. The code is available at https://github.com/zhmzm/Multi_Temperature_Verl.git.

Interprofessional education has long relied on case studies and the use of standardized patients to support teamwork, communication, and related collaborative competencies among healthcare professionals. However, traditional approaches are often limited by cost, scalability, and inability to mimic the dynamic complexity of real-world clinical scenarios. To address these challenges, we designed and developed AIMS (AI-Enhanced Immersive Multidisciplinary Simulations), a virtual simulation that integrates a large language model (Gemini-2.5-Flash), a Unity-based virtual environment engine, and a character creation pipeline to support synchronized, multimodal interactions between the user and the virtual patient. AIMS was designed to enhance collaborative clinical reasoning and health promotion competencies among students from pharmacy, medicine, nursing, and social work. A formal usability testing session was conducted which participants assumed professional roles on a healthcare team and engaged in a mix of scripted and unscripted conversations. Participants explored the patient's symptoms, social context, and care needs. Usability issues were identified (e.g., audio routing, response latency) and used to guide subsequent refinements. Findings in general suggest that AIMS supports realistic, profession-specific and contextually appropriate conversations. We discussed both technical and pedagogical innovations of AIMS and concluded with future directions.

The complexity of the Generally Accepted Accounting Principles (GAAP) and the hierarchical structure of eXtensible Business Reporting Language (XBRL) filings make financial auditing increasingly difficult to automate and verify. While large language models (LLMs) have demonstrated strong capabilities in unstructured text understanding, their ability to reason over structured, interdependent, and taxonomy-driven financial documents remains largely unexplored. To fill this gap, we introduce FinAuditing, the first taxonomy-aligned, structure-aware, multi-document benchmark for evaluating LLMs on financial auditing tasks. Built from real US-GAAP-compliant XBRL filings, FinAuditing defines three complementary subtasks, FinSM for semantic consistency, FinRE for relational consistency, and FinMR for numerical consistency, each targeting a distinct aspect of structured auditing reasoning. We further propose a unified evaluation framework integrating retrieval, classification, and reasoning metrics across these subtasks. Extensive zero-shot experiments on 13 state-of-the-art LLMs reveal that current models perform inconsistently across semantic, relational, and mathematical dimensions, with accuracy drops of up to 60-90% when reasoning over hierarchical multi-document structures. Our findings expose the systematic limitations of modern LLMs in taxonomy-grounded financial reasoning and establish FinAuditing as a foundation for developing trustworthy, structure-aware, and regulation-aligned financial intelligence systems. The benchmark dataset is available at Hugging Face.

A big part of the high - level programming repositories used by software developers over the world every day have more than 2000 files; the largest files from those repositories could have 5,000 or more lines of code -- those scales exceed LLM context window size by magnitude of 1,000 - 10,000 times. Based on such limitations, application of highly productive and smart LLM to large code bases becomes a challenge which stays at the front door of automatization of the software development process [8, 3]. Keeping this in mind, we developed a solution that allows us to apply a certain level of automatization and simplification of the development of large code bases for software developers. The most complete and main task that our system is capable of is automatic bug - fix and feature addition / enhancement using only a short user description. The given task can be split into two smaller tasks: (1) retrieval of relevant source code repository files to a Natural Language (NL) user query / issue description; (2) applying changes to a set of files selected in Step #1.

Quality estimation (QE) reranking is a form of quality-aware decoding which aims to improve machine translation (MT) by scoring and selecting the best candidate from a pool of generated translations. While known to be effective at the sentence level, its application to the increasingly prominent domain of document-level translation remains underexplored. In this work, we evaluate QE reranking performance on document-level (rather than the typical sentence-level) translation, using various learned and large language model (LLM)-based QE metrics. We find that with our best learned metric, SLIDE, BLEURT-20 scores improve by +2.00 with only two candidates, and by +5.09 with 32, across both decoder-only LLM models and encoder-decoder neural machine translation (NMT) models. Using the best LLM-based metric, GEMBA-DA, gains of +1.63 and +4.30 are achieved under the same conditions. Although gains shrink with longer inputs, reranking with 32 candidates yields improvements of +2.34 (SLIDE) and +1.40 (GEMBA-DA) on our longest documents (512-1024 source tokens). These findings demonstrate the practical value of document-level QE, with minimal runtime overhead given suitable translation models and hardware.

Peer review is the cornerstone of scientific publishing, yet it suffers from inconsistencies, reviewer subjectivity, and scalability challenges. We introduce ReviewerToo, a modular framework for studying and deploying AI-assisted peer review to complement human judgment with systematic and consistent assessments. ReviewerToo supports systematic experiments with specialized reviewer personas and structured evaluation criteria, and can be partially or fully integrated into real conference workflows. We validate ReviewerToo on a carefully curated dataset of 1,963 paper submissions from ICLR 2025, where our experiments with the gpt-oss-120b model achieves 81.8% accuracy for the task of categorizing a paper as accept/reject compared to 83.9% for the average human reviewer. Additionally, ReviewerToo-generated reviews are rated as higher quality than the human average by an LLM judge, though still trailing the strongest expert contributions. Our analysis highlights domains where AI reviewers excel (e.g., fact-checking, literature coverage) and where they struggle (e.g., assessing methodological novelty and theoretical contributions), underscoring the continued need for human expertise. Based on these findings, we propose guidelines for integrating AI into peer-review pipelines, showing how AI can enhance consistency, coverage, and fairness while leaving complex evaluative judgments to domain experts. Our work provides a foundation for systematic, hybrid peer-review systems that scale with the growth of scientific publishing.

Large language models (LLMs) remain vulnerable to multi-turn jailbreaking attacks that exploit conversational context to bypass safety constraints gradually. These attacks target different harm categories (like malware generation, harassment, or fraud) through distinct conversational approaches (educational discussions, personal experiences, hypothetical scenarios). Existing multi-turn jailbreaking methods often rely on heuristic or ad hoc exploration strategies, providing limited insight into underlying model weaknesses. The relationship between conversation patterns and model vulnerabilities across harm categories remains poorly understood. We propose Pattern Enhanced Chain of Attack (PE-CoA), a framework of five conversation patterns to construct effective multi-turn jailbreaks through natural dialogue. Evaluating PE-CoA on twelve LLMs spanning ten harm categories, we achieve state-of-the-art performance, uncovering pattern-specific vulnerabilities and LLM behavioral characteristics: models exhibit distinct weakness profiles where robustness to one conversational pattern does not generalize to others, and model families share similar failure modes. These findings highlight limitations of safety training and indicate the need for pattern-aware defenses. Code available on: https://github.com/Ragib-Amin-Nihal/PE-CoA

Modern codebases make it hard for developers and AI coding assistants to find the right source files when answering questions like "How does this feature work?" or "Where was the bug introduced?" Traditional code search (keyword or IR based) often misses semantic context and cross file links, while large language models (LLMs) understand natural language but lack repository specific detail. We present a method for file path retrieval that fine tunes a strong LLM (Qwen3-8B) with QLoRA and Unsloth optimizations to predict relevant file paths directly from a natural language query. To build training data, we introduce six code aware strategies that use abstract syntax tree (AST) structure and repository content to generate realistic question-answer pairs, where answers are sets of file paths. The strategies range from single file prompts to hierarchical repository summaries, providing broad coverage. We fine tune on Python projects including Flask, Click, Jinja, FastAPI, and PyTorch, and obtain high retrieval accuracy: up to 91\% exact match and 93\% recall on held out queries, clearly beating single strategy training. On a large codebase like PyTorch (about 4,000 Python files), the model reaches 59\% recall, showing scalability. We analyze how multi level code signals help the LLM reason over cross file context and discuss dataset design, limits (for example, context length in very large repos), and future integration of retrieval with LLM based code intelligence.