CycleGAN provides a framework to train image-to-image translation with unpaired datasets using cycle consistency loss [4]. While results are great in many applications, the pixel level cycle consistency can potentially be problematic and causes unrealistic images in certain cases. In this project, we propose three simple modifications to cycle consistency, and show that such an approach achieves better results with fewer artifacts.

Active learning aims to alleviate the amount of labor involved in data labeling by automating the selection of unlabeled samples via an acquisition function. For example, variational adversarial active learning (VAAL) leverages an adversarial network to discriminate unlabeled samples from labeled ones using latent space information. However, VAAL has the following shortcomings: (i) it does not exploit target task information, and (ii) unlabeled data is only used for sample selection rather than model training. To address these limitations, we introduce novel techniques that significantly improve the use of abundant unlabeled data during training and take into account the task information. Concretely, we propose an improved pseudo-labeling algorithm that leverages information from all unlabeled data in a semi-supervised manner, thus allowing a model to explore a richer data space. In addition, we develop a ranking-based loss prediction module that converts predicted relative ranking information into a differentiable ranking loss. This loss can be embedded as a rank variable into the latent space of a variational autoencoder and then trained with a discriminator in an adversarial fashion for sample selection. We demonstrate the superior performance of our approach over the state of the art on various image classification and segmentation benchmark datasets.

Medical image datasets in the real world are often unlabeled and imbalanced, and Semi-Supervised Object Detection (SSOD) can utilize unlabeled data to improve an object detector. However, existing approaches predominantly assumed that the unlabeled data and test data do not contain out-of-distribution (OOD) classes. The few open-set semi-supervised object detection methods have two weaknesses: first, the class imbalance is not considered; second, the OOD instances are distinguished and simply discarded during pseudo-labeling. In this paper, we consider the open-set semi-supervised object detection problem which leverages unlabeled data that contain OOD classes to improve object detection for medical images. Our study incorporates two key innovations: Category Control Embed (CCE) and out-of-distribution Detection Fusion Classifier (OODFC). CCE is designed to tackle dataset imbalance by constructing a Foreground information Library, while OODFC tackles open-set challenges by integrating the ``unknown'' information into basic pseudo-labels. Our method outperforms the state-of-the-art SSOD performance, achieving a 4.25 mAP improvement on the public Parasite dataset.

CycleGAN was trained on SynthRAD Grand Challenge Dataset using the single-epoch modification (SEM) method proposed in this paper which is referred to as (CycleGAN-single) compared to the usual method of training CycleGAN on around 200 epochs (CycleGAN-multi). Model performance were evaluated qualitatively and quantitatively with quantitative performance metrics like PSNR, SSIM, MAE and MSE. The consideration of both quantitative and qualitative performance when evaluating a model is unique to certain image-to-image translation tasks like medical imaging of patient data as detailed in this paper. Also, this paper shows that good quantitative performance does not always imply good qualitative performance and the converse is also not always True (i.e. good qualitative performance does not always imply good quantitative performance). This paper also proposes a lightweight model called FQGA (Fast Paired Image-to-Image Translation Quarter-Generator Adversary) which has 1/4 the number of parameters compared to CycleGAN (when comparing their Generator Models). FQGA outperforms CycleGAN qualitatively and quantitatively even only after training on 20 epochs. Finally, using SEM method on FQGA allowed it to again outperform CycleGAN both quantitatively and qualitatively. These performance gains even with fewer model parameters and fewer epochs (which will result in time and computational savings) may also be applicable to other image-to-image translation tasks in Machine Learning apart from the Medical image-translation task discussed in this paper between Cone Beam Computed Tomography (CBCT) and Computed Tomography (CT) images.

Recent advancements in digital pathology have led to the development of numerous foundational models that utilize self-supervised learning on patches extracted from gigapixel whole slide images (WSIs). While this approach leverages vast amounts of unlabeled data, we have discovered a significant issue: features extracted from these self-supervised models tend to cluster by individual WSIs, a phenomenon we term WSI-specific feature collapse. This problem can potentially limit the model's generalization ability and performance on various downstream tasks. To address this issue, we introduce EXAONEPath, a novel foundational model trained on patches that have undergone stain normalization. Stain normalization helps reduce color variability arising from different laboratories and scanners, enabling the model to learn more consistent features. EXAONEPath is trained using 285,153,903 patches extracted from a total of 34,795 WSIs. Our experiments demonstrate that EXAONEPath significantly mitigates the feature collapse problem, indicating that the model has learned more generalized features rather than overfitting to individual WSI characteristics. We compared EXAONEPath with state-of-the-art models across six downstream task datasets, and our results show that EXAONEPath achieves superior performance relative to the number of WSIs used and the model's parameter count. This suggests that the application of stain normalization has substantially improved the model's efficiency and generalization capabilities.

Co-training, extended from self-training, is one of the frameworks for semi-supervised learning. Without natural split of features, single-view co-training works at the cost of training extra classifiers, where the algorithm should be delicately designed to prevent individual classifiers from collapsing into each other. To remove these obstacles which deter the adoption of single-view co-training, we present a simple and efficient algorithm Multi-Head Co-Training. By integrating base learners into a multi-head structure, the model is in a minimal amount of extra parameters. Every classification head in the unified model interacts with its peers through a "Weak and Strong Augmentation" strategy, in which the diversity is naturally brought by the strong data augmentation. Therefore, the proposed method facilitates single-view co-training by 1). promoting diversity implicitly and 2). only requiring a small extra computational overhead. The effectiveness of Multi-Head Co-Training is demonstrated in an empirical study on standard semi-supervised learning benchmarks.

Contrastive representation learning, which aims to learnthe shared information between different views of unlabeled data by maximizing the mutual information between them, has shown its powerful competence in self-supervised learning for downstream tasks. However, recent works have demonstrated that more estimated mutual information does not guarantee better performance in different downstream tasks. Such works inspire us to conjecture that the learned representations not only maintain task-relevant information from unlabeled data but also carry task-irrelevant information which is superfluous for downstream tasks, thus leading to performance degeneration. In this paper we show that superfluous information does exist during the conventional contrastive learning framework, and further design a new objective, namely SuperInfo, to learn robust representations by a linear combination of both predictive and superfluous information. Besides, we notice that it is feasible to tune the coefficients of introduced losses to discard task-irrelevant information, while keeping partial non-shared task-relevant information according to our SuperInfo loss.We demonstrate that learning with our loss can often outperform the traditional contrastive learning approaches on image classification, object detection and instance segmentation tasks with significant improvements.

The Maximum Minimal Cut Problem (MMCP), a NP-hard combinatorial optimization (CO) problem, has not received much attention due to the demanding and challenging bi-connectivity constraint. Moreover, as a CO problem, it is also a daunting task for machine learning, especially without labeled instances. To deal with these problems, this work proposes an unsupervised learning framework combined with heuristics for MMCP that can provide valid and high-quality solutions. As far as we know, this is the first work that explores machine learning and heuristics to solve MMCP. The unsupervised solver is inspired by a relaxation-plus-rounding approach, the relaxed solution is parameterized by graph neural networks, and the cost and penalty of MMCP are explicitly written out, which can train the model end-to-end. A crucial observation is that each solution corresponds to at least one spanning tree. Based on this finding, a heuristic solver that implements tree transformations by adding vertices is utilized to repair and improve the solution quality of the unsupervised solver. Alternatively, the graph is simplified while guaranteeing solution consistency, which reduces the running time. We conduct extensive experiments to evaluate our framework and give a specific application. The results demonstrate the superiority of our method against two techniques designed.

Unsupervised learning has become an essential building block of AI systems. The representations it produces, e.g. in foundation models, are critical to a wide variety of downstream applications. It is therefore important to carefully examine unsupervised models to ensure not only that they produce accurate predictions, but also that these predictions are not "right for the wrong reasons", the so-called Clever Hans (CH) effect. Using specially developed Explainable AI techniques, we show for the first time that CH effects are widespread in unsupervised learning. Our empirical findings are enriched by theoretical insights, which interestingly point to inductive biases in the unsupervised learning machine as a primary source of CH effects. Overall, our work sheds light on unexplored risks associated with practical applications of unsupervised learning and suggests ways to make unsupervised learning more robust.

Laplacian learning method is a well-established technique in classical graph-based semi-supervised learning, but its potential in the quantum domain remains largely unexplored. This study investigates the performance of the Laplacian-based Quantum Semi-Supervised Learning (QSSL) method across four benchmark datasets -- Iris, Wine, Breast Cancer Wisconsin, and Heart Disease. Further analysis explores the impact of increasing Qubit counts, revealing that adding more Qubits to a quantum system doesn't always improve performance. The effectiveness of additional Qubits depends on the quantum algorithm and how well it matches the dataset. Additionally, we examine the effects of varying entangling layers on entanglement entropy and test accuracy. The performance of Laplacian learning is highly dependent on the number of entangling layers, with optimal configurations varying across different datasets. Typically, moderate levels of entanglement offer the best balance between model complexity and generalization capabilities. These observations highlight the crucial need for precise hyperparameter tuning tailored to each dataset to achieve optimal performance in Laplacian learning methods.