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 Regression


From Lasso regression to Feature vector machine

Neural Information Processing Systems

Lasso regression tends to assign zero weights to most irrelevant or redundant features, and hence is a promising technique for feature selection. Its limitation, however, is that it only offers solutions to linear models. Kernel machines with feature scaling techniques have been studied for feature selection with nonlinear models. However, such approaches require to solve hard non-convex optimization problems. This paper proposes a new approach named the Feature Vector Machine (FVM). It reformulates the standard Lasso regression into a form isomorphic to SVM, and this form can be easily extended for feature selection with nonlinear models by introducing kernels defined on feature vectors. FVM generates sparse solutions in the nonlinear feature space and it is much more tractable compared to feature scaling kernel machines. Our experiments with FVM on simulated data show encouraging results in identifying the small number of dominating features that are non-linearly correlated to the response, a task the standard Lasso fails to complete.


Worst-Case Bounds for Gaussian Process Models

Neural Information Processing Systems

We present a competitive analysis of some nonparametric Bayesian algorithms in a worst-case online learning setting, where no probabilistic assumptions about the generation of the data are made. We consider models which use a Gaussian process prior (over the space of all functions) and provide bounds on the regret (under the log loss) for commonly used nonparametric Bayesian algorithms -- including Gaussian regression and logistic regression -- which show how these algorithms can perform favorably under rather general conditions. These bounds explicitly handle the infinite dimensionality of these nonparametric classes in a natural way. We also make formal connections to the minimax and minimum description length (MDL) framework. Here, we show precisely how Bayesian Gaussian regression is a minimax strategy.


Nearest Neighbor Based Feature Selection for Regression and its Application to Neural Activity

Neural Information Processing Systems

We present a nonlinear, simple, yet effective, feature subset selection method for regression and use it in analyzing cortical neural activity. Our algorithm involves a feature-weighted version of the k-nearest-neighbor algorithm. It is able to capture complex dependency of the target function on its input and makes use of the leave-one-out error as a natural regularization. We explain the characteristics of our algorithm on synthetic problems and use it in the context of predicting hand velocity from spikes recorded in motor cortex of a behaving monkey. By applying feature selection we are able to improve prediction quality and suggest a novel way of exploring neural data.


Worst-Case Bounds for Gaussian Process Models

Neural Information Processing Systems

We present a competitive analysis of some nonparametric Bayesian algorithms in a worst-case online learning setting, where no probabilistic assumptions about the generation of the data are made. We consider models which use a Gaussian process prior (over the space of all functions) and provide bounds on the regret (under the log loss) for commonly used nonparametric Bayesian algorithms -- including Gaussian regression and logistic regression -- which show how these algorithms can perform favorably under rather general conditions. These bounds explicitly handle the infinite dimensionality of these nonparametric classes in a natural way. We also make formal connections to the minimax and minimum description length (MDL) framework. Here, we show precisely how Bayesian Gaussian regression is a minimax strategy.


Selecting Landmark Points for Sparse Manifold Learning

Neural Information Processing Systems

There has been a surge of interest in learning nonlinear manifold models to approximate high-dimensional data. Both for computational complexity reasons and for generalization capability, sparsity is a desired feature in such models. This usually means dimensionality reduction, which naturally implies estimating the intrinsic dimension, but it can also mean selecting a subset of the data to use as landmarks, which is especially important because many existing algorithms have quadratic complexity in the number of observations.


From Lasso regression to Feature vector machine

Neural Information Processing Systems

Lasso regression tends to assign zero weights to most irrelevant or redundant features, and hence is a promising technique for feature selection. Its limitation, however, is that it only offers solutions to linear models. Kernel machines with feature scaling techniques have been studied for feature selection with nonlinear models. However, such approaches require to solve hard non-convex optimization problems. This paper proposes a new approach named the Feature Vector Machine (FVM). It reformulates the standard Lasso regression into a form isomorphic to SVM, and this form can be easily extended for feature selection with nonlinear models by introducing kernels defined on feature vectors. FVM generates sparse solutions in the nonlinear feature space and it is much more tractable compared to feature scaling kernel machines. Our experiments with FVM on simulated data show encouraging results in identifying the small number of dominating features that are non-linearly correlated to the response, a task the standard Lasso fails to complete.


Large-scale biophysical parameter estimation in single neurons via constrained linear regression

Neural Information Processing Systems

Our understanding of the input-output function of single cells has been substantially advanced by biophysically accurate multi-compartmental models. The large number of parameters needing hand tuning in these models has, however, somewhat hampered their applicability and interpretability. Here we propose a simple and well-founded method for automatic estimation of many of these key parameters: 1) the spatial distribution of channel densities on the cell's membrane; 2) the spatiotemporal pattern of synaptic input; 3) the channels' reversal potentials; 4) the intercompartmental conductances; and 5) the noise level in each compartment. We assume experimental access to: a) the spatiotemporal voltage signal in the dendrite (or some contiguous subpart thereof, e.g.


Convex Neural Networks

Neural Information Processing Systems

Convexity has recently received a lot of attention in the machine learning community, and the lack of convexity has been seen as a major disadvantage of many learning algorithms, such as multi-layer artificial neural networks. We show that training multi-layer neural networks in which the number of hidden units is learned can be viewed as a convex optimization problem. This problem involves an infinite number of variables, but can be solved by incrementally inserting a hidden unit at a time, each time finding a linear classifier that minimizes a weighted sum of errors.


Learning Multiple Related Tasks using Latent Independent Component Analysis

Neural Information Processing Systems

We propose a probabilistic model based on Independent Component Analysis for learning multiple related tasks. In our model the task parameters are assumed to be generated from independent sources which account for the relatedness of the tasks. We use Laplace distributions to model hidden sources which makes it possible to identify the hidden, independent components instead of just modeling correlations. Furthermore, our model enjoys a sparsity property which makes it both parsimonious and robust. We also propose efficient algorithms for both empirical Bayes method and point estimation. Our experimental results on two multi-label text classification data sets show that the proposed approach is promising.


Noise and the two-thirds power Law

Neural Information Processing Systems

The two-thirds power law, an empirical law stating an inverse nonlinear relationship between the tangential hand speed and the curvature of its trajectory during curved motion, is widely acknowledged to be an invariant of upper-limb movement. It has also been shown to exist in eyemotion, locomotion and was even demonstrated in motion perception and prediction. This ubiquity has fostered various attempts to uncover the origins of this empirical relationship. In these it was generally attributed either to smoothness in hand-or joint-space or to the result of mechanisms that damp noise inherent in the motor system to produce the smooth trajectories evident in healthy human motion. We show here that white Gaussian noise also obeys this power-law. Analysis of signal and noise combinations shows that trajectories that were synthetically created not to comply with the power-law are transformed to power-law compliant ones after combination with low levels of noise. Furthermore, there exist colored noise types that drive non-power-law trajectories to power-law compliance and are not affected by smoothing. These results suggest caution when running experiments aimed at verifying the power-law or assuming its underlying existence without proper analysis of the noise. Our results could also suggest that the power-law might be derived not from smoothness or smoothness-inducing mechanisms operating on the noise inherent in our motor system but rather from the correlated noise which is inherent in this motor system.