When used to guide decisions, linear regression analysis typically involves estimation of regression coefficients via ordinary least squares and their subsequent use to make decisions. When there are multiple response variables and features do not perfectly capture their relationships, it is beneficial to account for the decision objective when computing regression coefficients. Empirical optimization does so but sacrifices performance when features are well-chosen or training data are insufficient. We propose directed regression, an efficient algorithm that combines merits of ordinary least squares and empirical optimization. We demonstrate through a computational study that directed regression can generate significant performance gains over either alternative. We also develop a theory that motivates the algorithm.

This paper addresses the important tradeoff between privacy and learnability, when designing algorithms for learning from private databases. First we apply an idea of Dwork et al. to design a specific privacy-preserving machine learning algorithm, logistic regression. This involves bounding the sensitivity of logistic regression, and perturbing the learned classifier with noise proportional to the sensitivity. Noting that the approach of Dwork et al. has limitations when applied to other machine learning algorithms, we then present another privacy-preserving logistic regression algorithm. The algorithm is based on solving a perturbed objective, and does not depend on the sensitivity. We prove that our algorithm preserves privacy in the model due to Dwork et al., and we provide a learning performance guarantee. Our work also reveals an interesting connection between regularization and privacy.

Many popular optimization algorithms, like the Levenberg-Marquardt algorithm (LMA), use heuristic-based controllers'' that modulate the behavior of the optimizer during the optimization process. For example, in the LMA a damping parameter is dynamically modified based on a set rules that were developed using various heuristic arguments. Reinforcement learning (RL) is a machine learning approach to learn optimal controllers by examples and thus is an obvious candidate to improve the heuristic-based controllers implicit in the most popular and heavily used optimization algorithms. Improving the performance of off-the-shelf optimizers is particularly important for time-constrained optimization problems. For example the LMA algorithm has become popular for many real-time computer vision problems, including object tracking from video, where only a small amount of time can be allocated to the optimizer on each incoming video frame. Here we show that a popular modern reinforcement learning technique using a very simply state space can dramatically improve the performance of general purpose optimizers, like the LMA. Most surprisingly the controllers learned for a particular domain appear to work very well also on very different optimization domains. For example we used RL methods to train a new controller for the damping parameter of the LMA. This controller was trained on a collection of classic, relatively small, non-linear regression problems. The modified LMA performed better than the standard LMA on these problems. Most surprisingly, it also dramatically outperformed the standard LMA on a difficult large scale computer vision problem for which it had not been trained before. Thus the controller appeared to have extracted control rules that were not just domain specific but generalized across a wide range of optimization domains."

High-dimensional statistical inference deals with models in which the the number ofparameters p is comparable to or larger than the sample size n. Since it is usually impossible to obtain consistent procedures unless p/n 0, a line of recent work has studied models with various types of structure (e.g., sparse vectors; block-structuredmatrices; low-rank matrices; Markov assumptions). In such settings, a general approach to estimation is to solve a regularized convex program (known as a regularized M-estimator) which combines a loss function (measuring how well the model fits the data) with some regularization function that encourages theassumed structure. The goal of this paper is to provide a unified framework forestablishing consistency and convergence rates for such regularized M-estimators under high-dimensional scaling. We state one main theorem and show how it can be used to re-derive several existing results, and also to obtain several new results on consistency and convergence rates. Our analysis also identifies two key properties of loss and regularization functions, referred to as restricted strong convexity and decomposability, that ensure the corresponding regularized M-estimators have fast convergence rates.

To estimate the changing structure of a varying-coefficient varying-structure (VCVS) model remains an important and open problem in dynamic system modelling, which includes learning trajectories of stock prices, or uncovering the topology of an evolving gene network. In this paper, we investigate sparsistent learning of a sub-family of this model --- piecewise constant VCVS models. We analyze two main issues in this problem: inferring time points where structural changes occur and estimating model structure (i.e., model selection) on each of the constant segments. We propose a two-stage adaptive procedure, which first identifies jump points of structural changes and then identifies relevant covariates to a response on each of the segments. We provide an asymptotic analysis of the procedure, showing that with the increasing sample size, number of structural changes, and number of variables, the true model can be consistently selected. We demonstrate the performance of the method on synthetic data and apply it to the brain computer interface dataset. We also consider how this applies to structure estimation of time-varying probabilistic graphical models.

Multitask learning addressed the problem of learning related tasks whose information can be shared each other. Traditional problem usually deal with homogeneous tasks such as regression, classification individually. In this paper we consider the problem learning multiple related tasks where tasks consist of both continuous and discrete outputs from a common set of input variables that lie in a high-dimensional space. All of the tasks are related in the sense that they share the same set of relevant input variables, but the amount of influence of each input on different outputs may vary. We formulate this problem as a combination of linear regression and logistic regression and model the joint sparsity as L1/Linf and L1/L2-norm of the model parameters. Among several possible applications, our approach addresses an important open problem in genetic association mapping, where we are interested in discovering genetic markers that influence multiple correlated traits jointly. In our experiments, we demonstrate our method in the scenario of association mapping, using simulated and asthma data, and show that the algorithm can effectively recover the relevant inputs with respect to all of the tasks.

This learning problem arises frequently in many application areas ranging from signal processing, computer vision, over robotics to computer graphics. We present a new algorithmic scheme for the solution of this general learning problem based on regularized empirical risk minimization. The regularization functional takes into account the geometry of input and output manifold, and we show that it implements a prior which is particularly natural. Moreover, we demonstrate that our algorithm performs well in a difficult surface registration problem.

For supervised and unsupervised learning, positive definite kernels allow to use large and potentially infinite dimensional feature spaces with a computational cost that only depends on the number of observations. This is usually done through the penalization of predictor functions by Euclidean or Hilbertian norms. In this paper, we explore penalizing by sparsity-inducing norms such as the L1-norm or the block L1-norm. We assume that the kernel decomposes into a large sum of individual basis kernels which can be embedded in a directed acyclic graph; we show that it is then possible to perform kernel selection through a hierarchical multiple kernel learning framework, in polynomial time in the number of selected kernels. This framework is naturally applied to non linear variable selection; our extensive simulations on synthetic datasets and datasets from the UCI repository show that efficiently exploring the large feature space through sparsity-inducing norms leads to state-of-the-art predictive performance.

We consider robust least-squares regression with feature-wise disturbance. We show that this formulation leads to tractable convex optimization problems, and we exhibit a particular uncertainty set for which the robust problem is equivalent to $\ell_1$ regularized regression (Lasso). This provides an interpretation of Lasso from a robust optimization perspective. We generalize this robust formulation to consider more general uncertainty sets, which all lead to tractable convex optimization problems. Therefore, we provide a new methodology for designing regression algorithms, which generalize known formulations. The advantage is that robustness to disturbance is a physical property that can be exploited: in addition to obtaining new formulations, we use it directly to show sparsity properties of Lasso, as well as to prove a general consistency result for robust regression problems, including Lasso, from a unified robustness perspective.

Factor analysis is the task of explaining data by means of a set of latentfactors.