An accurate model of patient survival time can help in the treatment and care of cancer patients. The common practice of providing survival time estimates based only on population averages for the site and stage of cancer ignores many important individual differences among patients. In this paper, we propose a local regression method for learning patient-specific survival time distribution based on patient attributes such as blood tests and clinical assessments. When tested on a cohort of more than 2000 cancer patients, our method gives survival time predictions that are much more accurate than popular survival analysis models such as the Cox and Aalen regression models. Our results also show that using patient-specific attributes can reduce the prediction error on survival time by as much as 20% when compared to using cancer site and stage only.

Despite the variety of robust regression methods that have been developed, current regression formulations are either NP-hard, or allow unbounded response to even a single leverage point. We present a general formulation for robust regression --Variational M-estimation--that unifies a number of robust regression methods while allowing a tractable approximation strategy. We develop an estimator that requires only polynomial-time, while achieving certain robustness and consistency guarantees. An experimental evaluation demonstrates the effectiveness of the new estimation approach compared to standard methods.

In categorical data there is often structure in the number of variables that take on each label. For example, the total number of objects in an image and the number of highly relevant documents per query in web search both tend to follow a structured distribution. In this paper, we study a probabilistic model that explicitly includes a prior distribution over such counts, along with a count-conditional likelihood that defines probabilities over all subsets of a given size. When labels are binary and the prior over counts is a Poisson-Binomial distribution, a standard logistic regression model is recovered, but for other count distributions, such priors induce global dependencies and combinatorics that appear to complicate learning and inference. However, we demonstrate that simple, efficient learning procedures can be derived for more general forms of this model.

The large amount of data collected in buildings makes energy management smarter and more energy efficient. This study proposes a design and implementation methodology of data-driven heating, ventilation, and air conditioning (HVAC) control. Building thermodynamics is modeled using a symbolic regression model (SRM) built from the collected data. Additionally, an HVAC system model is also developed with a data-driven approach. A model predictive control (MPC) based HVAC scheduling is formulated with the developed models to minimize energy consumption and peak power demand and maximize thermal comfort. The performance of the proposed framework is demonstrated in the workspace in the actual campus building. The HVAC system using the proposed framework reduces the peak power by 16.1\% compared to the widely used thermostat controller.

Past research has proposed numerous hardware prefetching techniques, most of which rely on exploiting one specific type of program context information (e.g., program counter, cacheline address) to predict future memory accesses. These techniques either completely neglect a prefetcher's undesirable effects (e.g., memory bandwidth usage) on the overall system, or incorporate system-level feedback as an afterthought to a system-unaware prefetch algorithm. We show that prior prefetchers often lose their performance benefit over a wide range of workloads and system configurations due to their inherent inability to take multiple different types of program context and system-level feedback information into account while prefetching. In this paper, we make a case for designing a holistic prefetch algorithm that learns to prefetch using multiple different types of program context and system-level feedback information inherent to its design. To this end, we propose Pythia, which formulates the prefetcher as a reinforcement learning agent. For every demand request, Pythia observes multiple different types of program context information to make a prefetch decision. For every prefetch decision, Pythia receives a numerical reward that evaluates prefetch quality under the current memory bandwidth usage. Pythia uses this reward to reinforce the correlation between program context information and prefetch decision to generate highly accurate, timely, and system-aware prefetch requests in the future. Our extensive evaluations using simulation and hardware synthesis show that Pythia outperforms multiple state-of-the-art prefetchers over a wide range of workloads and system configurations, while incurring only 1.03% area overhead over a desktop-class processor and no software changes in workloads. The source code of Pythia can be freely downloaded from https://github.com/CMU-SAFARI/Pythia.

Companies that have an online presence-in particular, companies that are exclusively digital-often subscribe to this business model: collect data from the user base, then expose the data to advertisement agencies in order to turn a profit. Such companies routinely market a service as "free", while obfuscating the fact that they tend to "charge" users in the currency of personal information rather than money. However, online companies also gather user data for more principled purposes, such as improving the user experience and aggregating statistics. The problem is the sale of user data to third parties. In this work, we design an intelligent approach to online privacy protection that leverages supervised learning. By detecting and blocking data collection that might infringe on a user's privacy, we can restore a degree of digital privacy to the user. In our evaluation, we collect a dataset of network requests and measure the performance of several classifiers that adhere to the supervised learning paradigm. The results of our evaluation demonstrate the feasibility and potential of our approach.

Causal discovery methods are intrinsically constrained by the set of assumptions needed to ensure structure identifiability. Moreover additional restrictions are often imposed in order to simplify the inference task: this is the case for the Gaussian noise assumption on additive non-linear models, which is common to many causal discovery approaches. In this paper we show the shortcomings of inference under this hypothesis, analyzing the risk of edge inversion under violation of Gaussianity of the noise terms. Then, we propose a novel method for inferring the topological ordering of the variables in the causal graph, from data generated according to an additive non-linear model with a generic noise distribution. This leads to NoGAM (Not only Gaussian Additive noise Models), a causal discovery algorithm with a minimal set of assumptions and state of the art performance, experimentally benchmarked on synthetic data.

In this PyTorch tutorial we will learn how to create Logistic Regression Classifier in PyTorch. Logistic regression is a type of regression that predicts the probability of an event. It is used for classification problems and has many applications in the fields of machine learning, artificial intelligence, and data mining. The formula of logistic regression is to apply a sigmoid function to the output of a linear function. This article discusses how you can build a logistic regression classifier.

Joint machine learning models that allow synthesizing and classifying data often offer uneven performance between those tasks or are unstable to train. In this work, we depart from a set of empirical observations that indicate the usefulness of internal representations built by contemporary deep diffusion-based generative models not only for generating but also predicting. We then propose to extend the vanilla diffusion model with a classifier that allows for stable joint end-to-end training with shared parameterization between those objectives. The resulting joint diffusion model outperforms recent state-of-the-art hybrid methods in terms of both classification and generation quality on all evaluated benchmarks. On top of our joint training approach, we present how we can directly benefit from shared generative and discriminative representations by introducing a method for visual counterfactual explanations.

Purpose: Robotic assistance in otologic surgery can reduce the task load of operating surgeons during the removal of bone around the critical structures in the lateral skull base. However, safe deployment into the anatomical passageways necessitates the development of advanced sensing capabilities to actively limit the interaction forces between the surgical tools and critical anatomy. Methods: We introduce a surgical drill equipped with a force sensor that is capable of measuring accurate tool-tissue interaction forces to enable force control and feedback to surgeons. The design, calibration and validation of the force-sensing surgical drill mounted on a cooperatively controlled surgical robot are described in this work. Results: The force measurements on the tip of the surgical drill are validated with raw-egg drilling experiments, where a force sensor mounted below the egg serves as ground truth. The average root mean square error (RMSE) for points and path drilling experiments are 41.7 (pm 12.2) mN and 48.3 (pm 13.7) mN respectively. Conclusions: The force-sensing prototype measures forces with sub-millinewton resolution and the results demonstrate that the calibrated force-sensing drill generates accurate force measurements with minimal error compared to the measured drill forces. The development of such sensing capabilities is crucial for the safe use of robotic systems in a clinical context.