Cardiovascular disease is the leading cause of death globally, resulting in 17 million deaths each year. Despite the availability of various treatment options, existing techniques based upon conventional medical knowledge often fail to identify patients who might have benefited from more aggressive therapy. In this paper, we describe and evaluate a novel unsupervised machine learning approach for cardiac risk stratification. The key idea of our approach is to avoid specialized medical knowledge, and assess patient risk using symbolic mismatch, a new metric to assess similarity in long-term time-series activity. We hypothesize that high risk patients can be identified using symbolic mismatch, as individuals in a population with unusual long-term physiological activity. We describe related approaches that build on these ideas to provide improved medical decision making for patients who have recently suffered coronary attacks. We first describe how to compute the symbolic mismatch between pairs of long term electrocardiographic (ECG) signals. This algorithm maps the original signals into a symbolic domain, and provides a quantitative assessment of the difference between these symbolic representations of the original signals. We then show how this measure can be used with each of a one-class SVM, a nearest neighbor classifier, and hierarchical clustering to improve risk stratification. We evaluated our methods on a population of 686 cardiac patients with available long-term electrocardiographic data. In a univariate analysis, all of the methods provided a statistically significant association with the occurrence of a major adverse cardiac event in the next 90 days. In a multivariate analysis that incorporated the most widely used clinical risk variables, the nearest neighbor and hierarchical clustering approaches were able to statistically significantly distinguish patients with a roughly two-fold risk of suffering a major adverse cardiac event in the next 90 days.

Many existing approaches employ one-vs-rest method to decompose a multi-label classification problem into a set of 2- class classification problems, one for each class. This method is valid in traditional single-label classification, it, however, incurs training inconsistency in multi-label classification, because in the latter a data point could belong to more than one class. In order to deal with this problem, in this work, we further develop classicalK-Nearest Neighbor classifier and propose a novel Class Balanced K-Nearest Neighbor approach for multi-label classification by emphasizing balanced usage of data from all the classes. In addition, we also propose a Class Balanced Linear Discriminant Analysis approach to address high-dimensional multi-label input data. Promising experimental results on three broadly used multi-label data sets demonstrate the effectiveness of our approach.

We analyze the estimation of information theoretic measures of continuous random variables such as: differential entropy, mutual information or Kullback-Leibler divergence. The objective of this paper is two-fold. First, we prove that the information theoretic measure estimates using the k-nearest-neighbor density estimation with fixed k converge almost surely, even though the k-nearest-neighbor density estimation with fixed k does not converge to its true measure. Second, we show that the information theoretic measure estimates do not converge for k growing linearly with the number of samples. Nevertheless, these nonconvergent estimates can be used for solving the two-sample problem and assessing if two random variables are independent. We show that the two-sample and independence tests based on these nonconvergent estimates compare favorably with the maximum mean discrepancy test and the Hilbert Schmidt independence criterion, respectively.

We study clustering algorithms based on neighborhood graphs on a random sample of data points. The question we ask is how such a graph should be constructed in order to obtain optimal clustering results. Which type of neighborhood graph should one choose, mutual k-nearest neighbor or symmetric k-nearest neighbor? What is the optimal parameter k? In our setting, clusters are defined as connected components of the t-level set of the underlying probability distribution. Clusters are said to be identified in the neighborhood graph if connected components in the graph correspond to the true underlying clusters. Using techniques from random geometric graph theory, we prove bounds on the probability that clusters are identified successfully, both in a noise-free and in a noisy setting. Those bounds lead to several conclusions. First, k has to be chosen surprisingly high (rather of the order n than of the order log n) to maximize the probability of cluster identification. Secondly, the major difference between the mutual and the symmetric k-nearest neighbor graph occurs when one attempts to detect the most significant cluster only.

In this paper, we present an application of neural networks in the renewable energy domain. We have developed a methodology for the daily prediction of global solar radiation on a horizontal surface. We use an ad-hoc time series preprocessing and a Multi-Layer Perceptron (MLP) in order to predict solar radiation at daily horizon. First results are promising with nRMSE < 21% and RMSE < 998 Wh/m2. Our optimized MLP presents prediction similar to or even better than conventional methods such as ARIMA techniques, Bayesian inference, Markov chains and k-Nearest-Neighbors approximators. Moreover we found that our data preprocessing approach can reduce significantly forecasting errors.

Multi-instance learning attempts to learn from a training set consisting of labeled bags each containing many unlabeled instances. Previous studies typically treat the instances in the bags as independently and identically distributed. However, the instances in a bag are rarely independent, and therefore a better performance can be expected if the instances are treated in an non-i.i.d. way that exploits the relations among instances. In this paper, we propose a simple yet effective multi-instance learning method, which regards each bag as a graph and uses a specific kernel to distinguish the graphs by considering the features of the nodes as well as the features of the edges that convey some relations among instances. The effectiveness of the proposed method is validated by experiments.

The quality of training data for knowledge discovery in databases (KDD) and data mining depends upon many factors, but handling missing values is considered to be a crucial factor in overall data quality. Today real world datasets contains missing values due to human, operational error, hardware malfunctioning and many other factors. The quality of knowledge extracted, learning and decision problems depend directly upon the quality of training data. By considering the importance of handling missing values in KDD and data mining tasks, in this paper we propose a novel Hybrid Missing values Imputation Technique (HMiT) using association rules mining and hybrid combination of k-nearest neighbor approach. To check the effectiveness of our HMiT missing values imputation technique, we also perform detail experimental results on real world datasets. Our results suggest that the HMiT technique is not only better in term of accuracy but it also take less processing time as compared to current best missing values imputation technique based on k-nearest neighbor approach, which shows the effectiveness of our missing values imputation technique.

Handling missing values in training datasets for constructing learning models or extracting useful information is considered to be an important research task in data mining and knowledge discovery in databases. In recent years, lot of techniques are proposed for imputing missing values by considering attribute relationships with missing value observation and other observations of training dataset. The main deficiency of such techniques is that, they depend upon single approach and do not combine multiple approaches, that why they are less accurate. To improve the accuracy of missing values imputation, in this paper we introduce a novel partial matching concept in association rules mining, which shows better results as compared to full matching concept that we described in our previous work. Our imputation technique combines the partial matching concept in association rules with k-nearest neighbor approach. Since this is a hybrid technique, therefore its accuracy is much better than as compared to those techniques which depend upon single approach. To check the efficiency of our technique, we also provide detail experimental results on number of benchmark datasets which show better results as compared to previous approaches.

The $k$th-nearest neighbor rule is arguably the simplest and most intuitively appealing nonparametric classification procedure. However, application of this method is inhibited by lack of knowledge about its properties, in particular, about the manner in which it is influenced by the value of $k$; and by the absence of techniques for empirical choice of $k$. In the present paper we detail the way in which the value of $k$ determines the misclassification error. We consider two models, Poisson and Binomial, for the training samples. Under the first model, data are recorded in a Poisson stream and are "assigned" to one or other of the two populations in accordance with the prior probabilities. In particular, the total number of data in both training samples is a Poisson-distributed random variable. Under the Binomial model, however, the total number of data in the training samples is fixed, although again each data value is assigned in a random way. Although the values of risk and regret associated with the Poisson and Binomial models are different, they are asymptotically equivalent to first order, and also to the risks associated with kernel-based classifiers that are tailored to the case of two derivatives. These properties motivate new methods for choosing the value of $k$.

The problem of supervised classification (or discrimination) with functional data is considered, with a special interest on the popular k-nearest neighbors (k-NN) classifier. First, relying on a recent result by Cerou and Guyader (2006), we prove the consistency of the k-NN classifier for functional data whose distribution belongs to a broad family of Gaussian processes with triangular covariance functions. Second, on a more practical side, we check the behavior of the k-NN method when compared with a few other functional classifiers. This is carried out through a small simulation study and the analysis of several real functional data sets. While no global "uniform" winner emerges from such comparisons, the overall performance of the k-NN method, together with its sound intuitive motivation and relative simplicity, suggests that it could represent a reasonable benchmark for the classification problem with functional data.