The use of artificial intelligence to enable precision medicine and decision support systems through the analysis of pathology images has the potential to revolutionize the diagnosis and treatment of cancer. Such applications will depend on models' abilities to capture the diverse patterns observed in pathology images. To address this challenge, we present Virchow, a foundation model for computational pathology. Using self-supervised learning empowered by the DINOv2 algorithm, Virchow is a vision transformer model with 632 million parameters trained on 1.5 million hematoxylin and eosin stained whole slide images from diverse tissue and specimen types, which is orders of magnitude more data than previous works. The Virchow model enables the development of a pan-cancer detection system with 0.949 overall specimen-level AUC across 17 different cancer types, while also achieving 0.937 AUC on 7 rare cancer types. The Virchow model sets the state-of-the-art on the internal and external image tile level benchmarks and slide level biomarker prediction tasks. The gains in performance highlight the importance of training on massive pathology image datasets, suggesting scaling up the data and network architecture can improve the accuracy for many high-impact computational pathology applications where limited amounts of training data are available.

Image-Text Matching (ITM) task, a fundamental vision-language (VL) task, suffers from the inherent ambiguity arising from multiplicity and imperfect annotations. Deterministic functions are not sufficiently powerful to capture ambiguity, prompting the exploration of probabilistic embeddings to tackle the challenge. However, the existing probabilistic ITM approach encounters two key shortcomings; the burden of heavy computations due to the Monte Carlo approximation, and the loss saturation issue in the face of abundant false negatives. To overcome the issues, this paper presents an improved Probabilistic Cross-Modal Embeddings (named PCME++) by introducing a new probabilistic distance with a closed-form solution. In addition, two optimization techniques are proposed to enhance PCME++ further: first, the incorporation of pseudo-positives to prevent the loss saturation problem under massive false negatives; second, mixed sample data augmentation for probabilistic matching. Experimental results on MS-COCO Caption and two extended benchmarks, CxC and ECCV Caption, demonstrate the effectiveness of PCME++ compared to state-of-the-art ITM methods. The robustness of PCME++ is also evaluated under noisy image-text correspondences. In addition, the potential applicability of PCME++ in automatic prompt tuning for zero-shot classification is shown. The code is available at https://github.com/naver-ai/pcmepp.

The rapid influx of data-driven models into the industrial sector has been facilitated by the proliferation of sensor technology, enabling the collection of vast quantities of data. However, leveraging these models for failure detection and prognosis poses significant challenges, including issues like missing values and class imbalances. Moreover, the cost sensitivity associated with industrial operations further complicates the application of conventional models in this context. This paper introduces a novel cost-sensitive transformer model developed as part of a systematic workflow, which also integrates a hybrid resampler and a regression-based imputer. After subjecting our approach to rigorous testing using the APS failure dataset from Scania trucks and the SECOM dataset, we observed a substantial enhancement in performance compared to state-of-the-art methods. Moreover, we conduct an ablation study to analyze the contributions of different components in our proposed method. Our findings highlight the potential of our method in addressing the unique challenges of failure prediction in industrial settings, thereby contributing to enhanced reliability and efficiency in industrial operations.

Gun violence is a pressing and growing human rights issue that affects nearly every dimension of the social fabric, from healthcare and education to psychology and the economy. Reliable data on firearm events is paramount to developing more effective public policy and emergency responses. However, the lack of comprehensive databases and the risks of in-person surveys prevent human rights organizations from collecting needed data in most countries. Here, we partner with a Brazilian human rights organization to conduct a systematic evaluation of language models to assist with monitoring real-world firearm events from social media data. We propose a fine-tuned BERT-based model trained on Twitter (now X) texts to distinguish gun violence reports from ordinary Portuguese texts. Our model achieves a high AUC score of 0.97. We then incorporate our model into a web application and test it in a live intervention. We study and interview Brazilian analysts who continuously fact-check social media texts to identify new gun violence events. Qualitative assessments show that our solution helped all analysts use their time more efficiently and expanded their search capacities. Quantitative assessments show that the use of our model was associated with more analysts' interactions with online users reporting gun violence. Taken together, our findings suggest that modern Natural Language Processing techniques can help support the work of human rights organizations.

In ambient assisted living, human activity recognition from time series sensor data mainly focuses on predefined activities, often overlooking new activity patterns. We propose CLAN, a two-tower contrastive learning-based novelty detection framework with diverse types of negative pairs for human activity recognition. It is tailored to challenges with human activity characteristics, including the significance of temporal and frequency features, complex activity dynamics, shared features across activities, and sensor modality variations. The framework aims to construct invariant representations of known activity robust to the challenges. To generate suitable negative pairs, it selects data augmentation methods according to the temporal and frequency characteristics of each dataset. It derives the key representations against meaningless dynamics by contrastive and classification losses-based representation learning and score function-based novelty detection that accommodate dynamic numbers of the different types of augmented samples. The proposed two-tower model extracts the representations in terms of time and frequency, mutually enhancing expressiveness for distinguishing between new and known activities, even when they share common features. Experiments on four real-world human activity datasets show that CLAN surpasses the best performance of existing novelty detection methods, improving by 8.3%, 13.7%, and 53.3% in AUROC, balanced accuracy, and FPR@TPR0.95 metrics respectively.

We explore the social and contextual factors that influence the outcome of person-to-person music recommendations and discovery. Specifically, we use data from Spotify to investigate how a link sent from one user to another results in the receiver engaging with the music of the shared artist. We consider several factors that may influence this process, such as the strength of the sender-receiver relationship, the user's role in the Spotify social network, their music social cohesion, and how similar the new artist is to the receiver's taste. We find that the receiver of a link is more likely to engage with a new artist when (1) they have similar music taste to the sender and the shared track is a good fit for their taste, (2) they have a stronger and more intimate tie with the sender, and (3) the shared artist is popular with the receiver's connections. Finally, we use these findings to build a Random Forest classifier to predict whether a shared music track will result in the receiver's engagement with the shared artist. This model elucidates which type of social and contextual features are most predictive, although peak performance is achieved when a diverse set of features are included. These findings provide new insights into the multifaceted mechanisms underpinning the interplay between music discovery and social processes.

Anomaly, or out-of-distribution, detection is a promising tool for aiding discoveries of new particles or processes in particle physics. In this work, we identify and address two overlooked opportunities to improve anomaly detection for high-energy physics. First, rather than train a generative model on the single most dominant background process, we build detection algorithms using representation learning from multiple background types, thus taking advantage of more information to improve estimation of what is relevant for detection. Second, we generalize decorrelation to the multi-background setting, thus directly enforcing a more complete definition of robustness for anomaly detection. We demonstrate the benefit of the proposed robust multi-background anomaly detection algorithms on a high-dimensional dataset of particle decays at the Large Hadron Collider.

We present a novel method for anomaly detection in Solar System object data, in preparation for the Legacy Survey of Space and Time. We train a deep autoencoder for anomaly detection and use the learned latent space to search for other interesting objects. We demonstrate the efficacy of the autoencoder approach by finding interesting examples, such as interstellar objects, and show that using the autoencoder, further examples of interesting classes can be found. We also investigate the limits of classic unsupervised approaches to anomaly detection through the generation of synthetic anomalies and evaluate the feasibility of using a supervised learning approach. Future work should consider expanding the feature space to increase the variety of anomalies that can be uncovered during the survey using an autoencoder.

It is believed that in knowledge distillation (KD), the role of the teacher is to provide an estimate for the unknown Bayes conditional probability distribution (BCPD) to be used in the student training process. Conventionally, this estimate is obtained by training the teacher using maximum log-likelihood (MLL) method. To improve this estimate for KD, in this paper we introduce the concept of conditional mutual information (CMI) into the estimation of BCPD and propose a novel estimator called the maximum CMI (MCMI) method. Specifically, in MCMI estimation, both the log-likelihood and CMI of the teacher are simultaneously maximized when the teacher is trained. Through Eigen-CAM, it is further shown that maximizing the teacher's CMI value allows the teacher to capture more contextual information in an image cluster. Via conducting a thorough set of experiments, we show that by employing a teacher trained via MCMI estimation rather than one trained via MLL estimation in various state-of-the-art KD frameworks, the student's classification accuracy consistently increases, with the gain of up to 3.32%. This suggests that the teacher's BCPD estimate provided by MCMI method is more accurate than that provided by MLL method. In addition, we show that such improvements in the student's accuracy are more drastic in zero-shot and few-shot settings. Notably, the student's accuracy increases with the gain of up to 5.72% when 5% of the training samples are available to the student (few-shot), and increases from 0% to as high as 84% for an omitted class (zero-shot). Knowledge distillation (Buciluǎ et al., 2006; Hinton et al., 2015) (KD) has received tremendous attention from both academia and industry in recent years as a highly effective model compression technique, and has been deployed in different settings (Radosavovic et al., 2018; Furlanello et al., 2018; Xie et al., 2020). The crux of KD is to distill the knowledge of a cumbersome model (teacher) into a lightweight model (student). One critical component of KD that has received relatively little attention is the training of the teacher model. In fact, in most of the existing KD methods, the teacher is trained to maximize its own performance, even though this does not necessarily lead to an improvement in the student's performance (Cho & Hariharan, 2019; Mirzadeh et al., 2020).

This paper introduces the Expected Booking (xB) model, a novel metric designed to estimate the likelihood of a foul resulting in a yellow card in football. Through three iterative experiments, employing ensemble methods, the model demonstrates improved performance with additional features and an expanded dataset. Analysis of FIFA World Cup 2022 data validates the model's efficacy in providing insights into team and player fouling tactics, aligning with actual defensive performance. The xB model addresses a gap in fouling efficiency examination, emphasizing defensive strategies which often overlooked. Further enhancements are suggested through the incorporation of comprehensive data and spatial features.