Network intrusion detection is one of the most important issues in the field of cyber security, and various machine learning techniques have been applied to build intrusion detection systems. However, since the number of features to describe the network connections is often large, where some features are redundant or noisy, feature selection is necessary in such scenarios, which can both improve the efficiency and accuracy. Recently, some researchers focus on using multi-objective evolutionary algorithms (MOEAs) to select features. But usually, they only consider the number of features and classification accuracy as the objectives, resulting in unsatisfactory performance on a critical metric, detection rate. This will lead to the missing of many real attacks and bring huge losses to the network system. In this paper, we propose DR-MOFS to model the feature selection problem in network intrusion detection as a three-objective optimization problem, where the number of features, accuracy and detection rate are optimized simultaneously, and use MOEAs to solve it. Experiments on two popular network intrusion detection datasets NSL-KDD and UNSW-NB15 show that in most cases the proposed method can outperform previous methods, i.e., lead to fewer features, higher accuracy and detection rate.

Large language models (LLMs) have demonstrated potential in the innovation of many disciplines. However, how they can best be developed for oncology remains underdeveloped. State-of-the-art OpenAI models were fine-tuned on a clinical dataset and clinical guidelines text corpus for two important cancer treatment factors, adjuvant radiation therapy and chemotherapy, using a novel Langchain prompt engineering pipeline. A high accuracy (0.85+) was achieved in the classification of adjuvant radiation therapy and chemotherapy for breast cancer patients. Furthermore, a confidence interval was formed from observational data on the quality of treatment from human oncologists to estimate the proportion of scenarios in which the model must outperform the original oncologist in its treatment prediction to be a better solution overall as 8.2% to 13.3%. Due to indeterminacy in the outcomes of cancer treatment decisions, future investigation, potentially a clinical trial, would be required to determine if this threshold was met by the models. Nevertheless, with 85% of U.S. cancer patients receiving treatment at local community facilities, these kinds of models could play an important part in expanding access to quality care with outcomes that lie, at minimum, close to a human oncologist.

In silico methods evaluating the mutation effects of missense mutations are providing an important approach for understanding mutations in personal genomes and identifying disease-relevant biomarkers. However, existing methods, including deep learning methods, heavily rely on sequence-aware information, and do not fully leverage the potential of available 3D structural information. In addition, these methods may exhibit an inability to predict mutations in domains difficult to formulate sequence-based embeddings. In this study, we introduce a novel rationale-guided graph neural network AlphaGMut to evaluate mutation effects and to distinguish pathogenic mutations from neutral mutations. We compute the alpha shapes of protein structures to obtain atomic-resolution edge connectivities and map them to an accurate residue-level graph representation. We then compute structural-, topological-, biophysical-, and sequence properties of the mutation sites, which are assigned as node attributes in the graph. These node attributes could effectively guide the graph neural network to learn the difference between pathogenic and neutral mutations using k-hop message passing with a short training period. We demonstrate that AlphaGMut outperforms state-of-the-art methods, including DeepMind's AlphaMissense, in many performance metrics. In addition, AlphaGMut has the advantage of performing well in alignment-free settings, which provides broader prediction coverage and better generalization compared to current methods requiring deep sequence-aware information.

This study assesses the ability of Large Vision-Language Models (LVLMs) to differentiate between AI-generated and human-generated images. It introduces a new automated benchmark construction method for this evaluation. The experiment compared common LVLMs with human participants using a mixed dataset of AI and human-created images. Results showed that LVLMs could distinguish between the image types to some extent but exhibited a rightward bias, and perform significantly worse compared to humans. To build on these findings, we developed an automated benchmark construction process using AI. This process involved topic retrieval, narrative script generation, error embedding, and image generation, creating a diverse set of text-image pairs with intentional errors. We validated our method through constructing two caparable benchmarks. This study highlights the strengths and weaknesses of LVLMs in real-world understanding and advances benchmark construction techniques, providing a scalable and automatic approach for AI model evaluation.

Electronic healthcare records are vital for patient safety as they document conditions, plans, and procedures in both free text and medical codes. Language models have significantly enhanced the processing of such records, streamlining workflows and reducing manual data entry, thereby saving healthcare providers significant resources. However, the black-box nature of these models often leaves healthcare professionals hesitant to trust them. State-of-the-art explainability methods increase model transparency but rely on human-annotated evidence spans, which are costly. In this study, we propose an approach to produce plausible and faithful explanations without needing such annotations. We demonstrate on the automated medical coding task that adversarial robustness training improves explanation plausibility and introduce AttInGrad, a new explanation method superior to previous ones. By combining both contributions in a fully unsupervised setup, we produce explanations of comparable quality, or better, to that of a supervised approach. We release our code and model weights.

Efficient and current roadway geometry data collection is a critical task for transportation agencies to undertake effective road planning, maintenance, design, and rehabilitation efforts. The methods for gathering such data can be broadly classified into two categories: a) land-based methods, which encompass field inventory, mobile mapping, and image logging, and b) aerial-based methods, which involve satellite imagery, drones, and laser scanning. However, employing land-based techniques for extensive highway networks covering thousands of miles proves arduous and costly, and poses safety risks for crew members. Consequently, there exists a pressing need to develop more efficient methodologies for acquiring this data promptly, safely, and economically. Fortunately, with the increasing availability of high-resolution images and recent strides in computer vision and object detection technologies, automated extraction of roadway geometry features has become feasible.

The fairness of AI decision-making has garnered increasing attention, leading to the proposal of numerous fairness algorithms. In this paper, we aim not to address this issue by directly introducing fair learning algorithms, but rather by generating entirely new, fair synthetic data from biased datasets for use in any downstream tasks. Additionally, the distribution of test data may differ from that of the training set, potentially impacting the performance of the generated synthetic data in downstream tasks. To address these two challenges, we propose a diffusion model-based framework, FADM: Fairness-Aware Diffusion with Meta-training. FADM introduces two types of gradient induction during the sampling phase of the diffusion model: one to ensure that the generated samples belong to the desired target categories, and another to make the sensitive attributes of the generated samples difficult to classify into any specific sensitive attribute category. To overcome data distribution shifts in the test environment, we train the diffusion model and the two classifiers used for induction within a meta-learning framework. Compared to other baselines, FADM allows for flexible control over the categories of the generated samples and exhibits superior generalization capability. Experiments on real datasets demonstrate that FADM achieves better accuracy and optimal fairness in downstream tasks.

Data-centric AI focuses on understanding and utilizing high-quality, relevant data in training machine learning (ML) models, thereby increasing the likelihood of producing accurate and useful results. Automatic feature augmentation, aiming to augment the initial base table with useful features from other tables, is critical in data preparation as it improves model performance, robustness, and generalizability. While recent works have investigated automatic feature augmentation, most of them have limited capabilities in utilizing all useful features as many of them are in candidate tables not directly joinable with the base table. Worse yet, with numerous join paths leading to these distant features, existing solutions fail to fully exploit them within a reasonable compute budget. We present FeatNavigator, an effective and efficient framework that explores and integrates high-quality features in relational tables for ML models. FeatNavigator evaluates a feature from two aspects: (1) the intrinsic value of a feature towards an ML task (i.e., feature importance) and (2) the efficacy of a join path connecting the feature to the base table (i.e., integration quality). FeatNavigator strategically selects a small set of available features and their corresponding join paths to train a feature importance estimation model and an integration quality prediction model. Furthermore, FeatNavigator's search algorithm exploits both estimated feature importance and integration quality to identify the optimized feature augmentation plan. Our experimental results show that FeatNavigator outperforms state-of-the-art solutions on five public datasets by up to 40.1% in ML model performance.

The goal for classification is to correctly assign labels to unseen samples. However, most methods misclassify samples with unseen labels and assign them to one of the known classes. Open-Set Classification (OSC) algorithms aim to maximize both closed and open-set recognition capabilities. Recent studies showed the utility of such algorithms on small-scale data sets, but limited experimentation makes it difficult to assess their performances in real-world problems. Here, we provide a comprehensive comparison of various OSC algorithms, including training-based (SoftMax, Garbage, EOS) and post-processing methods (Maximum SoftMax Scores, Maximum Logit Scores, OpenMax, EVM, PROSER), the latter are applied on features from the former. We perform our evaluation on three large-scale protocols that mimic real-world challenges, where we train on known and negative open-set samples, and test on known and unknown instances. Our results show that EOS helps to improve performance of almost all post-processing algorithms. Particularly, OpenMax and PROSER are able to exploit better-trained networks, demonstrating the utility of hybrid models. However, while most algorithms work well on negative test samples -- samples of open-set classes seen during training -- they tend to perform poorly when tested on samples of previously unseen unknown classes, especially in challenging conditions.

Trusting the accuracy of data inputted on online platforms can be difficult due to the possibility of malicious websites gathering information for unlawful reasons. Analyzing each website individually becomes challenging with the presence of such malicious sites, making it hard to efficiently list all Uniform Resource Locators (URLs) on a blacklist. This ongoing challenge emphasizes the crucial need for strong security measures to safeguard against potential threats and unauthorized data collection. To detect the risk posed by malicious websites, it is proposed to utilize Machine Learning (ML)-based techniques. To this, we used several ML techniques such as Hist Gradient Boosting Classifier (HGBC), K-Nearest Neighbor (KNN), Logistic Regression (LR), Decision Tree (DT), Random Forest (RF), Multi-Layer Perceptron (MLP), Light Gradient Boosting Machine (LGBM), and Support Vector Machine (SVM) for detection of the benign and malicious website dataset. The dataset used contains 1781 records of malicious and benign website data with 13 features. First, we investigated missing value imputation on the dataset. Then, we normalized this data by scaling to a range of zero and one. Next, we utilized the Synthetic Minority Oversampling Technique (SMOTE) to balance the training data since the data set was unbalanced. After that, we applied ML algorithms to the balanced training set. Meanwhile, all algorithms were optimized based on grid search. Finally, the models were evaluated based on accuracy, precision, recall, F1 score, and the Area Under the Curve (AUC) metrics. The results demonstrated that the HGBC classifier has the best performance in terms of the mentioned metrics compared to the other classifiers.