Privacy-preserving synthetic data has been increasingly adopted to share data within and across organizations while reducing privacy risks. The intuition is to train a generative model on the real data, draw samples from the model, and create new (synthetic) data points. As the original data may contain sensitive and/or personal information, synthetic data can be vulnerable to membership/property inference, reconstruction attacks, etc. [6, 13, 25, 29, 30, 57]. Thus, models should be trained to satisfy robust definitions like Differential Privacy (DP) [19, 20], which bounds the privacy leakage from the synthetic data. Combining generative models with DP has been advocated for or deployed by government agencies [2, 31, 46, 62], regulatory bodies [60, 61], and non-profit organizations [48, 63].

Obstructive sleep apnea (OSA) is frequent and responsible for cardiovascular complications and excessive daytime sleepiness. It is underdiagnosed due to the difficulty to access the gold standard for diagnosis, polysomnography (PSG). Alternative methods using smartphone sensors could be useful to increase diagnosis. The objective is to assess the performances of Apneal, an application that records the sound using a smartphone's microphone and movements thanks to a smartphone's accelerometer and gyroscope, to estimate patients' AHI. In this article, we perform a monocentric proof-of-concept study with a first manual scoring step, and then an automatic detection of respiratory events from the recorded signals using a sequential deep-learning model which was released internally at Apneal at the end of 2022 (version 0.1 of Apneal automatic scoring of respiratory events), in adult patients during in-hospital polysomnography.46 patients (women 34 per cent, mean BMI 28.7 kg per m2) were included. For AHI superior to 15, sensitivity of manual scoring was 0.91, and positive predictive value (PPV) 0.89. For AHI superior to 30, sensitivity was 0.85, PPV 0.94. We obtained an AUC-ROC of 0.85 and an AUC-PR of 0.94 for the identification of AHI superior to 15, and AUC-ROC of 0.95 and AUC-PR of 0.93 for AHI superior to 30. Promising results are obtained for the automatic annotations of events.This article shows that manual scoring of smartphone-based signals is possible and accurate compared to PSG-based scorings. Automatic scoring method based on a deep learning model provides promising results. A larger multicentric validation study, involving subjects with different SAHS severity is required to confirm these results.

In sequential event prediction, which finds applications in finance, retail, social networks, and healthcare, a crucial task is forecasting multiple future events within a specified time horizon. Traditionally, this has been addressed through autoregressive generation using next-event prediction models, such as Marked Temporal Point Processes. However, autoregressive methods use their own output for future predictions, potentially reducing quality as the prediction horizon extends. In this paper, we challenge traditional approaches by introducing a novel benchmark, HoTPP, specifically designed to evaluate a model's ability to predict event sequences over a horizon. This benchmark features a new metric inspired by object detection in computer vision, addressing the limitations of existing metrics in assessing models with imprecise time-step predictions. Our evaluations on established datasets employing various models demonstrate that high accuracy in next-event prediction does not necessarily translate to superior horizon prediction, and vice versa. HoTPP aims to serve as a valuable tool for developing more robust event sequence prediction methods, ultimately paving the way for further advancements in the field.

In this work, we propose a two-phased approach for real-time detection and deterrence of ransomware. To achieve this, we leverage the capabilities of eBPF (Extended Berkeley Packet Filter) and artificial intelligence to develop both proactive and reactive methods. In the first phase, we utilize signature based detection, where we employ custom eBPF programs to trace the execution of new processes and perform hash-based analysis against a known ransomware dataset. In the second, we employ a behavior-based technique that focuses on monitoring the process activities using a custom eBPF program and the creation of ransom notes, a prominent indicator of ransomware activity through the use of Natural Language Processing (NLP). By leveraging low-level tracing capabilities of eBPF and integrating NLP based machine learning algorithms, our solution achieves an impressive 99.76% accuracy in identifying ransomware incidents within a few seconds on the onset of zero-day attacks.

We use (multi)modal deep neural networks (DNNs) to probe for sites of multimodal integration in the human brain by predicting stereoencephalography (SEEG) recordings taken while human subjects watched movies. We operationalize sites of multimodal integration as regions where a multimodal vision-language model predicts recordings better than unimodal language, unimodal vision, or linearly-integrated language-vision models. Our target DNN models span different architectures (e.g., convolutional networks and transformers) and multimodal training techniques (e.g., cross-attention and contrastive learning). As a key enabling step, we first demonstrate that trained vision and language models systematically outperform their randomly initialized counterparts in their ability to predict SEEG signals. We then compare unimodal and multimodal models against one another. Because our target DNN models often have different architectures, number of parameters, and training sets (possibly obscuring those differences attributable to integration), we carry out a controlled comparison of two models (SLIP and SimCLR), which keep all of these attributes the same aside from input modality. Using this approach, we identify a sizable number of neural sites (on average 141 out of 1090 total sites or 12.94%) and brain regions where multimodal integration seems to occur. Additionally, we find that among the variants of multimodal training techniques we assess, CLIP-style training is the best suited for downstream prediction of the neural activity in these sites.

Large Language Models (LLMs) are routinely used in retrieval-augmented applications to orchestrate tasks and process inputs from users and other sources. These inputs, even in a single LLM interaction, can come from a variety of sources, of varying trustworthiness and provenance. This opens the door to prompt injection attacks, where the LLM receives and acts upon instructions from supposedly data-only sources, thus deviating from the user's original instructions. We define this as task drift, and we propose to catch it by scanning and analyzing the LLM's activations. We compare the LLM's activations before and after processing the external input in order to detect whether this input caused instruction drift. We develop two probing methods and find that simply using a linear classifier can detect drift with near perfect ROC AUC on an out-of-distribution test set. We show that this approach generalizes surprisingly well to unseen task domains, such as prompt injections, jailbreaks, and malicious instructions, without being trained on any of these attacks. Our setup does not require any modification of the LLM (e.g., fine-tuning) or any text generation, thus maximizing deployability and cost efficiency and avoiding reliance on unreliable model output. To foster future research on activation-based task inspection, decoding, and interpretability, we will release our large-scale TaskTracker toolkit, comprising a dataset of over 500K instances, representations from 4 SoTA language models, and inspection tools.

This work addresses limitations in recent 3D tracking-by-detection methods, focusing on identifying legitimate trajectories and addressing state estimation drift in Kalman filters. Current methods rely heavily on threshold-based filtering of false positive detections using detection scores to prevent ghost trajectories. However, this approach is inadequate for distant and partially occluded objects, where detection scores tend to drop, potentially leading to false positives exceeding the threshold. Additionally, the literature generally treats detections as precise localizations of objects. Our research reveals that noise in detections impacts localization information, causing trajectory drift for occluded objects and hindering recovery. To this end, we propose a novel online track validity mechanism that temporally distinguishes between legitimate and ghost tracks, along with a multi-stage observational gating process for incoming observations. This mechanism significantly improves tracking performance, with a $6.28\%$ in HOTA and a $17.87\%$ increase in MOTA. We also introduce a refinement to the Kalman filter that enhances noise mitigation in trajectory drift, leading to more robust state estimation for occluded objects. Our framework, RobMOT, outperforms state-of-the-art methods, including deep learning approaches, across various detectors, achieving up to a $4\%$ margin in HOTA and $6\%$ in MOTA. RobMOT excels under challenging conditions, such as prolonged occlusions and tracking distant objects, with up to a 59\% improvement in processing latency.

Kolmogorov-Arnold Networks (KANs) have very recently been introduced into the world of machine learning, quickly capturing the attention of the entire community. However, KANs have mostly been tested for approximating complex functions or processing synthetic data, while a test on real-world tabular datasets is currently lacking. In this paper, we present a benchmarking study comparing KANs and Multi-Layer Perceptrons (MLPs) on tabular datasets. The study evaluates task performance and training times. From the results obtained on the various datasets, KANs demonstrate superior or comparable accuracy and F1 scores, excelling particularly in datasets with numerous instances, suggesting robust handling of complex data. We also highlight that this performance improvement of KANs comes with a higher computational cost when compared to MLPs of comparable sizes.

Considering the increased workload in pathology laboratories today, automated tools such as artificial intelligence models can help pathologists with their tasks and ease the workload. In this paper, we are proposing a segmentation model (DRU-Net) that can provide a delineation of human non-small cell lung carcinomas and an augmentation method that can improve classification results. The proposed model is a fused combination of truncated pre-trained DenseNet201 and ResNet101V2 as a patch-wise classifier followed by a lightweight U-Net as a refinement model. We have used two datasets (Norwegian Lung Cancer Biobank and Haukeland University Hospital lung cancer cohort) to create our proposed model. The DRU-Net model achieves an average of 0.91 Dice similarity coefficient. The proposed spatial augmentation method (multi-lens distortion) improved the network performance by 3%. Our findings show that choosing image patches that specifically include regions of interest leads to better results for the patch-wise classifier compared to other sampling methods. The qualitative analysis showed that the DRU-Net model is generally successful in detecting the tumor. On the test set, some of the cases showed areas of false positive and false negative segmentation in the periphery, particularly in tumors with inflammatory and reactive changes.

Understanding complex phenomena often requires analyzing high-dimensional data to uncover emergent properties that arise from multifactorial interactions. Here, we present EMUSES (Emerging-properties Mapping Using Spatial Embedding Statistics), an innovative approach employing Uniform Manifold Approximation and Projection (UMAP) to create high-dimensional embeddings that reveal latent structures within data. EMUSES facilitates the exploration and prediction of emergent properties by statistically analyzing these latent spaces. Using three distinct datasets--a handwritten digits dataset from the National Institute of Standards and Technology (NIST, E. Alpaydin, 1998), the Chicago Face Database (Ma et al., 2015), and brain disconnection data post-stroke (Talozzi et al., 2023)--we demonstrate EMUSES' effectiveness in detecting and interpreting emergent properties. Our method not only predicts outcomes with high accuracy but also provides clear visualizations and statistical insights into the underlying interactions within the data. By bridging the gap between predictive accuracy and interpretability, EMUSES offers researchers a powerful tool to understand the multifactorial origins of complex phenomena.