Pulmonary embolism (PE) is a leading cause of preventable in-hospital mortality. Advances in diagnosis, risk stratification, and prevention can improve outcomes. There are few large publicly available datasets that contain PE labels for research. Using the MIMIC-IV database, we extracted all available radiology reports of computed tomography pulmonary angiography (CTPA) scans and two physicians manually labeled the results as PE positive (acute PE) or PE negative. We then applied a previously finetuned Bio_ClinicalBERT transformer language model, VTE-BERT, to extract labels automatically. We verified VTE-BERT's reliability by measuring its performance against manual adjudication. We also compared the performance of VTE-BERT to diagnosis codes. We found that VTE-BERT has a sensitivity of 92.4% and positive predictive value (PPV) of 87.8% on all 19,942 patients with CTPA radiology reports from the emergency room and/or hospital admission. In contrast, diagnosis codes have a sensitivity of 95.4% and PPV of 83.8% on the subset of 11,990 hospitalized patients with discharge diagnosis codes. We successfully add nearly 20,000 labels to CTPAs in a publicly available dataset and demonstrate the external validity of a semi-supervised language model in accelerating hematologic research.

AI slop is flowing onto every major platform where people post online--and Medium is no exception. The 12-year-old publishing platform has undertaken a dizzying number of pivots over the years. It's finally on a financial upswing, having turned a monthly profit for the first time this summer. Medium CEO Tony Stubblebine and other executives at the company have described the platform as "a home for human writing." But there is evidence that robot bloggers are increasingly flocking to the platform, too.

We present the results of the "Fast Calorimeter Simulation Challenge 2022" -- the CaloChallenge. We study state-of-the-art generative models on four calorimeter shower datasets of increasing dimensionality, ranging from a few hundred voxels to a few tens of thousand voxels. The 31 individual submissions span a wide range of current popular generative architectures, including Variational AutoEncoders (VAEs), Generative Adversarial Networks (GANs), Normalizing Flows, Diffusion models, and models based on Conditional Flow Matching. We compare all submissions in terms of quality of generated calorimeter showers, as well as shower generation time and model size. To assess the quality we use a broad range of different metrics including differences in 1-dimensional histograms of observables, KPD/FPD scores, AUCs of binary classifiers, and the log-posterior of a multiclass classifier. The results of the CaloChallenge provide the most complete and comprehensive survey of cutting-edge approaches to calorimeter fast simulation to date. In addition, our work provides a uniquely detailed perspective on the important problem of how to evaluate generative models. As such, the results presented here should be applicable for other domains that use generative AI and require fast and faithful generation of samples in a large phase space.

Gliomas, the most common primary brain tumors, show high heterogeneity in histological and molecular characteristics. Accurate molecular profiling, like isocitrate dehydrogenase (IDH) mutation and 1p/19q codeletion, is critical for diagnosis, treatment, and prognosis. This review evaluates MRI-based deep learning (DL) models' efficacy in predicting these biomarkers. Following PRISMA guidelines, we systematically searched major databases (PubMed, Scopus, Ovid, and Web of Science) up to February 2024, screening studies that utilized DL to predict IDH and 1p/19q codeletion status from MRI data of glioma patients. We assessed the quality and risk of bias using the radiomics quality score and QUADAS-2 tool. Our meta-analysis used a bivariate model to compute pooled sensitivity, specificity, and meta-regression to assess inter-study heterogeneity. Of the 565 articles, 57 were selected for qualitative synthesis, and 52 underwent meta-analysis. The pooled estimates showed high diagnostic performance, with validation sensitivity, specificity, and area under the curve (AUC) of 0.84 [prediction interval (PI): 0.67-0.93, I2=51.10%, p < 0.05], 0.87 [PI: 0.49-0.98, I2=82.30%, p < 0.05], and 0.89 for IDH prediction, and 0.76 [PI: 0.28-0.96, I2=77.60%, p < 0.05], 0.85 [PI: 0.49-0.97, I2=80.30%, p < 0.05], and 0.90 for 1p/19q prediction, respectively. Meta-regression analyses revealed significant heterogeneity influenced by glioma grade, data source, inclusion of non-radiomics data, MRI sequences, segmentation and feature extraction methods, and validation techniques. DL models demonstrate strong potential in predicting molecular biomarkers from MRI scans, with significant variability influenced by technical and clinical factors. Thorough external validation is necessary to increase clinical utility.

As the scale of training corpora for large language models (LLMs) grows, model developers become increasingly reluctant to disclose details on their data. This lack of transparency poses challenges to scientific evaluation and ethical deployment. Recently, pretraining data detection approaches, which infer whether a given text was part of an LLM's training data through black-box access, have been explored. The Min-K\% Prob method, which has achieved state-of-the-art results, assumes that a non-training example tends to contain a few outlier words with low token probabilities. However, the effectiveness may be limited as it tends to misclassify non-training texts that contain many common words with high probabilities predicted by LLMs. To address this issue, we introduce a divergence-based calibration method, inspired by the divergence-from-randomness concept, to calibrate token probabilities for pretraining data detection. We compute the cross-entropy (i.e., the divergence) between the token probability distribution and the token frequency distribution to derive a detection score. We have developed a Chinese-language benchmark, PatentMIA, to assess the performance of detection approaches for LLMs on Chinese text. Experimental results on English-language benchmarks and PatentMIA demonstrate that our proposed method significantly outperforms existing methods. Our code and PatentMIA benchmark are available at \url{https://github.com/zhang-wei-chao/DC-PDD}.

Large language models can produce highly fluent paraphrases while retaining much of the original meaning. While this capability has a variety of helpful applications, it may also be abused by bad actors, for example to plagiarize content or to conceal their identity. This motivates us to consider the problem of paraphrase inversion: given a paraphrased document, attempt to recover the original text. To explore the feasibility of this task, we fine-tune paraphrase inversion models, both with and without additional author-specific context to help guide the inversion process. We explore two approaches to author-specific inversion: one using in-context examples of the target author's writing, and another using learned style representations that capture distinctive features of the author's style. We show that, when starting from paraphrased machine-generated text, we can recover significant portions of the document using a learned inversion model. When starting from human-written text, the variety of source writing styles poses a greater challenge for invertability. However, even when the original tokens can't be recovered, we find the inverted text is stylistically similar to the original, which significantly improves the performance of plagiarism detectors and authorship identification systems that rely on stylistic markers.

Artificial intelligence (AI), and especially its sub-field of Machine Learning (ML), are impacting the daily lives of everyone with their ubiquitous applications. In recent years, AI researchers and practitioners have introduced principles and guidelines to build systems that make reliable and trustworthy decisions. From a practical perspective, conventional ML systems process historical data to extract the features that are consequently used to train ML models that perform the desired task. However, in practice, a fundamental challenge arises when the system needs to be operationalized and deployed to evolve and operate in real-life environments continuously. To address this challenge, Machine Learning Operations (MLOps) have emerged as a potential recipe for standardizing ML solutions in deployment. Although MLOps demonstrated great success in streamlining ML processes, thoroughly defining the specifications of robust MLOps approaches remains of great interest to researchers and practitioners. In this paper, we provide a comprehensive overview of the trustworthiness property of MLOps systems. Specifically, we highlight technical practices to achieve robust MLOps systems. In addition, we survey the existing research approaches that address the robustness aspects of ML systems in production. We also review the tools and software available to build MLOps systems and summarize their support to handle the robustness aspects. Finally, we present the open challenges and propose possible future directions and opportunities within this emerging field. The aim of this paper is to provide researchers and practitioners working on practical AI applications with a comprehensive view to adopt robust ML solutions in production environments.

The advent of Large Language Models LLMs marks a milestone in Artificial Intelligence, altering how machines comprehend and generate human language. However, LLMs are vulnerable to malicious prompt injection attacks, where crafted inputs manipulate the models behavior in unintended ways, compromising system integrity and causing incorrect outcomes. Conventional detection methods rely on static, rule-based approaches, which often fail against sophisticated threats like abnormal token sequences and alias substitutions, leading to limited adaptability and higher rates of false positives and false negatives.This paper proposes a novel NLP based approach for prompt injection detection, emphasizing accuracy and optimization through a layered input screening process. In this framework, prompts are filtered through three distinct layers rule-based, ML classifier, and companion LLM before reaching the target model, thereby minimizing the risk of malicious interaction.Tests show the ML classifier achieves the highest accuracy among individual layers, yet the multi-layer framework enhances overall detection accuracy by reducing false negatives. Although this increases false positives, it minimizes the risk of overlooking genuine injected prompts, thus prioritizing security.This multi-layered detection approach highlights LLM vulnerabilities and provides a comprehensive framework for future research, promoting secure interactions between humans and AI systems.

Abstract--Modern day audio signal classification techniques lack the ability to classify low feature audio signals in the form of spectrographic temporal frequency data representations. Additionally, currently utilized techniques rely on full diverse data sets that are often not representative of real-world distributions. This paper derives several first-of-its-kind machine learning methodologies to analyze these low feature audio spectrograms given data distributions that may have normalized, skewed, or even limited training sets. In particular, this paper proposes several novel customized convolutional architectures to extract identifying features using binary, one-class, and siamese approaches to identify the spectrographic signature of a given audio signal. Utilizing these novel convolutional architectures as well as the proposed classification methods, these experiments demonstrate state-of-the-art classification accuracy and improved efficiency than traditional audio classification methods.

Readers can have different goals with respect to the text they are reading. Can these goals be decoded from the pattern of their eye movements over the text? In this work, we examine for the first time whether it is possible to decode two types of reading goals that are common in daily life: information seeking and ordinary reading. Using large scale eye-tracking data, we apply to this task a wide range of state-of-the-art models for eye movements and text that cover different architectural and data representation strategies, and further introduce a new model ensemble. We systematically evaluate these models at three levels of generalization: new textual item, new participant, and the combination of both. We find that eye movements contain highly valuable signals for this task. We further perform an error analysis which builds on prior empirical findings on differences between ordinary reading and information seeking and leverages rich textual annotations. This analysis reveals key properties of textual items and participant eye movements that contribute to the difficulty of the task.