In the dynamic landscape of project management, scope changes are an inevitable reality that can significantly impact project performance. These changes, whether initiated by stakeholders, external factors, or internal project dynamics, can lead to cost overruns and schedule delays. Accurately predicting the consequences of these changes is crucial for effective project control and informed decision-making. This study aims to develop predictive models to estimate the impact of scope changes on project cost and schedule using machine learning techniques. The research utilizes a comprehensive dataset containing detailed information on project tasks, including the Work Breakdown Structure (WBS), task type, productivity rate, estimated cost, actual cost, duration, task dependencies, scope change magnitude, and scope change timing. Multiple machine learning models are developed and evaluated to predict the impact of scope changes on project cost and schedule. These models include Linear Regression, Decision Tree, Ridge Regression, Random Forest, Gradient Boosting, and XGBoost. The dataset is split into training and testing sets, and the models are trained using the preprocessed data. Model robustness and generalization are assessed using cross-validation techniques. To evaluate the performance of models, we use Mean Squared Error (MSE) and R2. Residual plots are generated to assess the goodness of fit and identify any patterns or outliers. Hyperparameter tuning is performed to optimize the XGBoost model and improve its predictive accuracy. The study identifies the most influential project attributes in determining the magnitude of cost and schedule deviations caused by scope modifications. It is identified that productivity rate, scope change magnitude, task dependencies, estimated cost, actual cost, duration, and specific WBS elements are powerful predictors.

The adoption of large language models (LLMs) in many applications, from customer service chat bots and software de - velopment assistants to more capable agentic systems neces - sitates research into how to secure these systems. Attacks l ike prompt injection and jailbreaking attempt to elicit respon ses and actions from these models that are not compliant with the safety, privacy, or content policies of organizations u sing the model in their application. In order to counter abuse of LLMs for generating potentially harmful replies or taking u n-desirable actions, LLM owners must apply safeguards during training and integrate additional tools to block the LLM fro m generating text that abuses the model. Jailbreaking prompt s play a vital role in convincing an LLM to generate potentially harmful content, making it important to identify jai l-breaking attempts to block any further steps. In this work, w e propose a novel approach to detect jailbreak prompts based on pairing text embeddings well-suited for retrieval with t ra-ditional machine learning classification algorithms. Our a p-proach outperforms all publicly available methods from ope n source LLM security applications.

The p16/Ki-67 dual staining method is a new approach for cervical cancer screening with high sensitivity and specificity. However, there are issues of mis-detection and inaccurate recognition when the YOLOv5s algorithm is directly applied to dual-stained cell images. This paper Proposes a novel cervical cancer dual-stained image recognition (DSIR-YOLO) model based on an YOLOv5. By fusing the Swin-Transformer module, GAM attention mechanism, multi-scale feature fusion, and EIoU loss function, the detection performance is significantly improved, with mAP@0.5 and mAP@0.5:0.95 reaching 92.6% and 70.5%, respectively. Compared with YOLOv5s in five-fold cross-validation, the accuracy, recall, mAP@0.5, and mAP@0.5:0.95 of the improved algorithm are increased by 2.3%, 4.1%, 4.3%, and 8.0%, respectively, with smaller variances and higher stability. Compared with other detection algorithms, DSIR-YOLO in this paper sacrifices some performance requirements to improve the network recognition effect. In addition, the influence of dataset quality on the detection results is studied. By controlling the sealing property of pixels, scale difference, unlabelled cells, and diagonal annotation, the model detection accuracy, recall, mAP@0.5, and mAP@0.5:0.95 are improved by 13.3%, 15.3%, 18.3%, and 30.5%, respectively.

Recent research has generated hope that inference scaling could allow weaker language models to match or exceed the accuracy of stronger models, such as by repeatedly sampling solutions to a coding problem until it passes unit tests. The central thesis of this paper is that there is no free lunch for inference scaling: indefinite accuracy improvement through resampling can only be realized if the "verifier" (in this case, a set of unit tests) is perfect. When the verifier is imperfect, as it almost always is in domains such as reasoning or coding (for example, unit tests have imperfect coverage), there is a nonzero probability of false positives: incorrect solutions that pass the verifier. Resampling cannot decrease this probability, so it imposes an upper bound to the accuracy of resampling-based inference scaling even with an infinite compute budget. We find that there is a very strong correlation between the model's single-sample accuracy (i.e. accuracy without unit tests) and its false positive rate on coding benchmarks HumanEval and MBPP, whose unit tests have limited coverage. Therefore, no amount of inference scaling of weaker models can enable them to match the single-sample accuracy of a sufficiently strong model (Fig. 1a). When we consider that false positives have a negative utility compared to abstaining from producing a solution, it bends the inference scaling curve further downward. Empirically, we find that the optimal number of samples can be less than 10 under realistic assumptions (Fig. 1b). Finally, we show that beyond accuracy, false positives may have other undesirable qualities, such as poor adherence to coding style conventions.

Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for diagnostic purposes; however, they are now recognized for their potential in molecular profiling, which provides deeper insights into cancer prognosis and treatment response. Recent advancements in artificial intelligence (AI) have enabled digital pathology to analyze histopathologic images for both targeted molecular and broader omic biomarkers, marking a pivotal step in personalized cancer care. These technologies offer the capability to extract various biomarkers such as genomic, transcriptomic, proteomic, and metabolomic markers directly from the routine hematoxylin and eosin (H&E) stained images, which can support treatment decisions without the need for costly molecular assays. In this work, we provide a comprehensive review of AI-driven techniques for biomarker detection, with a focus on diverse omic biomarkers that allow novel biomarker discovery. Additionally, we analyze the major challenges faced in this field for robust algorithm development. These challenges highlight areas where further research is essential to bridge the gap between AI research and clinical application.

While Transformers have revolutionized machine learning on various data, existing Transformers for temporal graphs face limitations in (1) restricted receptive fields, (2) overhead of subgraph extraction, and (3) suboptimal generalization capability beyond link prediction. In this paper, we rethink temporal graph Transformers and propose TGTOD, a novel end-to-end Temporal Graph Transformer for Outlier Detection. TGTOD employs global attention to model both structural and temporal dependencies within temporal graphs. To tackle scalability, our approach divides large temporal graphs into spatiotemporal patches, which are then processed by a hierarchical Transformer architecture comprising Patch Transformer, Cluster Transformer, and Temporal Transformer. We evaluate TGTOD on three public datasets under two settings, comparing with a wide range of baselines. Our experimental results demonstrate the effectiveness of TGTOD, achieving AP improvement of 61% on Elliptic. Furthermore, our efficiency evaluation shows that TGTOD reduces training time by 44x compared to existing Transformers for temporal graphs. To foster reproducibility, we make our implementation publicly available at https://github.com/kayzliu/tgtod.

To combat the rising energy consumption of recommender systems we implement a novel alternative for k-fold cross validation. This alternative, named e-fold cross validation, aims to minimize the number of folds to achieve a reduction in power usage while keeping the reliability and robustness of the test results high. We tested our method on 5 recommender system algorithms across 6 datasets and compared it with 10-fold cross validation. On average e-fold cross validation only needed 41.5% of the energy that 10-fold cross validation would need, while it's results only differed by 1.81%. We conclude that e-fold cross validation is a promising approach that has the potential to be an energy efficient but still reliable alternative to k-fold cross validation.

In many applications it is important that a classification model not only has high accuracy but that a user is also provided with a reliable estimate of confidence in the predicted label. Calibration is a concept that is often invoked to provide such confidence estimates to a user. As such, calibration is a notion that is inherently aimed at human interpretation. In binary classification, a perfectly calibrated model f provides the guarantee that if it predicts fpxq " p on some instance x, then among the set of all instances on which f assigns this value p the probability of label 1 is indeed p (and the probability of label 0 thus 1 p). While calibration is generally considered useful, we would argue that in many cases, even if achieved, it is doomed to fail at its original goal of providing insight to a human user: for most suitably complex classification models, a human user that observes fpxq " p has no notion of the set of all instances on which f also outputs p.

As the ubiquity of smart mobile devices continues to rise, Optical Camera Communication systems have gained more attention as a solution for efficient and private data streaming. This system utilizes optical cameras to receive data from digital screens via visible light. Despite their promise, most of them are hindered by dynamic factors such as screen refreshing and rapid camera motion. CMOS cameras, often serving as the receivers, suffer from limited frame rates and motion-induced image blur, which degrade overall performance. To address these challenges, this paper unveils a novel system that utilizes event cameras. We introduce a dynamic visual marker and design event-based tracking algorithms to achieve fast localization and data streaming. Remarkably, the event camera's unique capabilities mitigate issues related to screen refresh rates and camera motion, enabling a high throughput of up to 114 Kbps in static conditions, and a 1 cm localization accuracy with 1% bit error rate under various camera motions.

As opaque black-box predictive models become more prevalent, the need to develop interpretations for these models is of great interest. The concept of variable importance and Shapley values are interpretability measures that applies to any predictive model and assesses how much a variable or set of variables improves prediction performance. When the number of variables is large, estimating variable importance presents a significant computational challenge because re-training neural networks or other black-box algorithms requires significant additional computation. In this paper, we address this challenge for algorithms using gradient descent and gradient boosting (e.g. neural networks, gradient-boosted decision trees). By using the ideas of early stopping of gradient-based methods in combination with warm-start using the dropout method, we develop a scalable method to estimate variable importance for any algorithm that can be expressed as an iterative kernel update equation. Importantly, we provide theoretical guarantees by using the theory for early stopping of kernel-based methods for neural networks with sufficiently large (but not necessarily infinite) width and gradient-boosting decision trees that use symmetric trees as a weaker learner. We also demonstrate the efficacy of our methods through simulations and a real data example which illustrates the computational benefit of early stopping rather than fully re-training the model as well as the increased accuracy of our approach.